Dr Dervila Glynn University positionCambridge Neuroscience Strategic Manager DepartmentsResearch ThemeInterestsFollowing on from a degree in Biotechnology, I completed a PhD in Pharmacology (Downing College) and worked for 11 years in the field of Huntington’s disease (HD). My research focused on understanding the mechanisms underlying neurodegeneration and abnormal behaviour in HD. I left the bench in December 2011 and joined Cambridge Neuroscience. Cambridge Neuroscience is an Interdisciplinary Research Centre within the University of Cambridge connecting >800 researchers across the University, who are involved with research into the nervous system. My position as Cambridge Neuroscience Strategic Manager involves working with academics from across the University to support the interdisciplinary scientific community in neuroscience. This involves workshops, seminars, facilitating introductions and external interactions, an interactive website, communications and public engagement. Research Focus
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Key publicationsGlynn D, Morton AJ (2011), “Synaptic Dysfunction in Huntington’s disease” Folding for the synapse 233-255 Glynn D, Gibson HE, Harte MK, Reim K, Jones S, Reynolds GP, Morton AJ (2010), “Clorgyline-mediated reversal of neurological deficits in a Complexin 2 knockout mouse.” Hum Mol Genet Details Glynn D, Reim K, Brose N, Morton AJ (2007), “Depletion of Complexin II does not affect disease progression in a mouse model of Huntington's disease (HD); support for role for complexin II in behavioural pathology in a mouse model of HD.” Brain Res Bull 72(2-3):108-20 Details Glynn D, Sizemore RJ, Morton AJ (2007), “Early motor development is abnormal in complexin 1 knockout mice.” Neurobiol Dis 25(3):483-95 Details Glynn D, Drew CJ, Reim K, Brose N, Morton AJ (2005), “Profound ataxia in complexin I knockout mice masks a complex phenotype that includes exploratory and habituation deficits” Human Molecular Genetics 14(16):2369-85 Details Publications2011Wood NI, Glynn D, Morton AJ (2011), “"Brain training" improves cognitive performance and survival in a transgenic mouse model of Huntington's disease.” Neurobiol Dis 42(3):427-37 PDF Details 2009Morton AJ, Glynn D, Leavens W, Zheng Z, Faull RL, Skepper JN, Wight JM (2009), “Paradoxical delay in the onset of disease caused by super-long CAG repeat expansions in R6/2 mice.” Neurobiol Dis 33(3):331-41 Details 2003Glynn D, Bortnick RA, Morton AJ (2003), “Complexin II is essential for normal neurological function in mice.” Hum Mol Genet 12(19):2431-48 Details |