Institute

Research Theme Lifelong Brain Development and Brain Ageing Neurons, Circuits and Networks

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Dr Sarah Mason

University Position

Research Associate

Interests

My research interests are: 1) Better defining the neuropsychological profile of presymptomatic and early Huntington's disease using fMRI scanning and behavioural testing. With a particular interest in determining the factors which underpin the cognitive heterogeneity of the disease. 2) Understanding the role of apathy in Huntington's disease, how it evolves with advancing disease and its relationship to cognitive processes such as reward processing, decision making and emotional. 3) Exploring social cognition in Huntington's disease.

Key Publications

Development and external validation of a prognostic model in newly diagnosed Parkinson disease.

DOI: http://doi.org/10.1212/WNL.0000000000002437
Journal: Neurology
E-pub date: 15 Mar 2016
Authors: DC Velseboer, RMA de Bie, L Wieske, JR Evans, SL Mason, T Foltynie, B Schmand, RJ de Haan, B Post, RA Barker, CH Williams-Gray

The CamPaIGN study of Parkinson’s disease: 10-year outlook in an incident population-based cohort.

DOI: http://doi.org/10.1136/jnnp-2013-305277
Journal: J Neurol Neurosurg Psychiatry
E-pub date: 1 Nov 2013
Authors: CH Williams-Gray, SL Mason, JR Evans, T Foltynie, C Brayne, TW Robbins, RA Barker

Publications

Parkinson’s disease and spirituality.

DOI: http://doi.org/10.3233/NRE-192947
Journal: NeuroRehabilitation
E-pub date: 1 Aug 2020
Authors: C Redfern, SL Mason, RA Barker, A Coles

Validation of a UPDRS-/MDS-UPDRS-based definition of functional dependency for Parkinson’s disease.

DOI: http://doi.org/10.1016/j.parkreldis.2020.05.034
Journal: Parkinsonism Relat Disord
E-pub date: 1 Jul 2020
Authors: N Ramsay, AD Macleod, G Alves, M Camacho, L Forsgren, RA Lawson, J Maple-Grødem, O-B Tysnes, CH Williams-Gray, AJ Yarnall, CE Counsell, Parkinson's Incidence Cohorts Collaboration, PINE Study, CamPaIGN study, PICNICS study, NYPUM Study, ParkWest Study: ParkWest Principal investigators, Study personnel, ICICLE-PD Study

Motor complications in Parkinson’s disease: 13-year follow-up of the CamPaIGN cohort.

DOI: http://doi.org/10.1002/mds.27882
Journal: Mov Disord
E-pub date: 1 Jan 2020
Authors: H-J Kim, S Mason, T Foltynie, S Winder-Rhodes, RA Barker, CH Williams-Gray

Portrait of blood-derived extracellular vesicles in patients with Parkinson’s disease.

DOI: http://doi.org/10.1016/j.nbd.2018.11.002
Journal: Neurobiol Dis
E-pub date: 1 Apr 2019
Authors: J Lamontagne-Proulx, I St-Amour, R Labib, J Pilon, HL Denis, N Cloutier, F Roux-Dalvai, AT Vincent, SL Mason, C Williams-Gray, A-C Duchez, A Droit, S Lacroix, N Dupré, M Langlois, S Chouinard, M Panisset, RA Barker, E Boilard, F Cicchetti

An open-label study to assess the feasibility and tolerability of rilmenidine for the treatment of Huntington’s disease.

DOI: http://doi.org/10.1007/s00415-017-8647-0
Journal: J Neurol
E-pub date: 1 Dec 2017
Authors: BR Underwood, ZW Green-Thompson, PJ Pugh, SE Lazic, SL Mason, J Griffin, PS Jones, JB Rowe, DC Rubinsztein, RA Barker

Specifically neuropathic Gaucher’s mutations accelerate cognitive decline in Parkinson’s.

DOI: http://doi.org/10.1002/ana.24781
Journal: Ann Neurol
E-pub date: 1 Nov 2016
Authors: G Liu, B Boot, JJ Locascio, IE Jansen, S Winder-Rhodes, S Eberly, A Elbaz, A Brice, B Ravina, JJ van Hilten, F Cormier-Dequaire, J-C Corvol, RA Barker, P Heutink, J Marinus, CH Williams-Gray, CR Scherzer, International Genetics of Parkinson Disease Progression (IGPP) Consortium

Comparative epidemiology of incident Parkinson’s disease in Cambridgeshire, UK.

DOI: http://doi.org/10.1136/jnnp-2015-312581
Journal: J Neurol Neurosurg Psychiatry
E-pub date: 1 Sep 2016
Authors: JR Evans, G Cummins, DP Breen, T Foltynie, SL Mason, CEG Brayne, CH Williams-Gray, RA Barker

Which patients with Parkinson’s disease participate in clinical trials? One centre’s experiences with a new cell based therapy trial (TRANSEURO).

DOI: http://doi.org/10.3233/JPD-140432
Journal: J Parkinsons Dis
E-pub date: 1 Aug 2014
Authors: SF Moore, NV Guzman, SL Mason, CH Williams-Gray, RA Barker

Excessive daytime sleepiness and its risk factors in incident Parkinson’s disease.

DOI: http://doi.org/10.1136/jnnp-2012-304097
Journal: J Neurol Neurosurg Psychiatry
E-pub date: 1 Feb 2013
Authors: DP Breen, CH Williams-Gray, SL Mason, T Foltynie, RA Barker

Glucocerebrosidase mutations influence the natural history of Parkinson’s disease in a community-based incident cohort.

DOI: http://doi.org/10.1093/brain/aws318
Journal: Brain
E-pub date: 1 Feb 2013
Authors: SE Winder-Rhodes, JR Evans, M Ban, SL Mason, CH Williams-Gray, T Foltynie, R Duran, NE Mencacci, SJ Sawcer, RA Barker

Addenbrooke’s Cognitive Examination-Revised for mild cognitive impairment in Parkinson’s disease.

DOI: http://doi.org/10.1002/mds.25084
Journal: Movement Disorders
E-pub date: 1 Aug 2012
Authors: P McColgan, JR Evans, DP Breen, SL Mason, RA Barker, CH Williams-Gray

LONGITUDINAL EVALUATION OF EXCESSIVE DAYTIME SLEEPINESS AND ITS RISK FACTORS IN PARKINSON’S DISEASE

DOI: http://doi.org/10.1136/jnnp-2011-301993.149
Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
E-pub date: 1 Mar 2012
Authors: DP Breen, JR Evans, CH Williams-Gray, SL Mason, T Foltynie, RA Barker

THE UTILITY OF THE ADDENBROOKE’S COGNITIVE EXAMINATION-REVISED (ACE-R) IN PARKINSON’S DISEASE

DOI: http://doi.org/10.1136/jnnp-2011-301993.3
Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
E-pub date: 1 Mar 2012
Authors: P McColgan, J Evans, DP Breen, SL Mason, B Ghosh, T Rittman, J Rowe, P Nestor, RA Barker, CH Williams-Gray