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EMAIL aeh33@cam.ac.uk
Department
  • Clinical Neurosciences
    • ORCID iDClick to view ORCID profile
    Research Theme Neurons, Circuits and Networks Beyond the Neuron
    Research Focus

    Keywords

  • Neuroinflammation
  • Microdialysis

    • Clinical Conditions

  • Stroke
  • Traumatic brain injury

    • Equipment & Techniques

  • Cross-sectional and cohort studies

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    Mr Adel Helmy PhD FRCS (SN)

    University Position
    Associate Professor
    Mr Adel Helmy is pleased to consider applications from prospective PhD students.

    Interests

    My research interests are in Acute Brain Injury (Traumatic Brain Injury (TBI) and Subarachnoid Haemorrhage (SAH)) and in particular the innate inflammatory response following TBI. Inflammation plays a role in secondary injury following TBI, but is also the starting point for reparative processes. I also have an interest in cerebral metabolism multi-modality monitoring as a means of refining and personalising treatment for patients. I am closely involved with the TBI-REPORTER Experimental Medicine Network

    Associated News Items

    Key Publications

    Consensus statement from the 2025 Delphi panel on cerebral microdialysis in critical care

    DOI: http://doi.org/10.1186/s13054-026-05993-z
    Journal: Critical Care
    E-pub date: 13 Apr 2026
    Authors: A Helmy, MS Baker, PJ Hutchinson

    Hyperostosis in meningioma: a retrospective exploration of histological correlates

    DOI: http://doi.org/10.1080/02688697.2024.2400134
    Journal: Br J Neurosurg
    E-pub date: 1 Feb 2026
    Authors: W Cook, A Helmy

    Health-related quality-of-life outcomes in CNS WHO grade 2 and 3 meningioma: a systematic review.

    DOI: http://doi.org/10.1007/s10143-025-03420-5
    Journal: Neurosurgical Review
    E-pub date: 27 Feb 2025
    Authors: WH Cook, F Khalil, CS Gillespie, AE Helmy

    Machine learning for predicting post-operative outcomes in meningiomas: a systematic review and meta-analysis.

    DOI: http://doi.org/10.1007/s00701-024-06344-z
    Journal: Acta Neurochir (Wien)
    E-pub date: 17 Dec 2024
    Authors: SY Abualnaja, JS Morris, H Rashid, WH Cook, AE Helmy

    Intra-operative extracorporeal irradiation of tumour-invaded craniotomy bone flap in meningioma: a case series.

    DOI: http://doi.org/10.1007/s00701-024-06126-7
    Journal: Acta Neurochir (Wien)
    E-pub date: 24 May 2024
    Authors: WH Cook, K Burton, SJ Jefferies, SL Duke, R Jena, NG Burnet, RW Kirollos, AE Helmy, T Santarius

    Publications

    A Meta-epidemiologic Analysis of Differences in Treatment-Effect Estimates According to Outcome Scale (GOS vs. GOSE) in Moderate-to-Severe Traumatic Brain Injury Trials.

    DOI: http://doi.org/10.1007/s12028-026-02634-9
    Journal: Neurocrit Care
    E-pub date: 21 Aug 2026
    Authors: NG Raccagni, M Dotti, YA Lightfoot, R Loda, MS Baker, JM Heihre, A Helmy, R Cinotti, G Citerio

    Defining metabolic abnormalities in acute human traumatic brain injury with cerebral microdialysis and multimodality monitoring.

    DOI: http://doi.org/10.1371/journal.pone.0331310
    Journal: PLoS One
    E-pub date: 1 Aug 2025
    Authors: MS Baker, S Venturini, C Lindblad, JM Heihre, I Timofeev, MR Guilfoyle, PJ Hutchinson, KLH Carpenter, A Helmy

    Multimodality Monitoring for the Management of Severe Traumatic Brain Injury

    DOI: http://doi.org/10.1016/j.nec.2025.03.013
    Journal: Neurosurg Clin N Am
    E-pub date: 1 Jul 2025
    Authors: MS Baker, KLH Carpenter, A Helmy, PJ Hutchinson

    Customised pre-operative cranioplasty to achieve maximal surgical resection of tumours with osseous involvement-a case series.

    DOI: http://doi.org/10.1007/s00701-024-06055-5
    Journal: Acta Neurochir (Wien)
    E-pub date: 27 Mar 2024
    Authors: S Jain, A Helmy, T Santarius, N Owen, K Grieve, P Hutchinson, I Timofeev

    Use of Mixed Reality in Neurosurgery Training: A Single Centre Experience.

    DOI: http://doi.org/10.1016/j.wneu.2023.04.107
    Journal: World Neurosurg
    E-pub date: 31 Aug 2023
    Authors: S Jain, I Timofeev, RW Kirollos, A Helmy

    Assessment of Accuracy of Mixed Reality Device for Neuronavigation: Proposed Methodology and Results

    DOI: http://doi.org/10.1227/neuprac.0000000000000036
    Journal: Neurosurg Pract
    E-pub date: 1 Jun 2023
    Authors: S Jain, T Tajsic, T Das, Y Gao, KY Ngiam, TT Yeo, M Graves, A Helmy

    Giant aneurysm arising from a cortical middle cerebral artery branch presenting as an extra-axial tumour: a case report.

    DOI: http://doi.org/10.1093/jscr/rjad210
    Journal: J Surg Case Rep
    E-pub date: 1 Apr 2023
    Authors: S Jain, T Paschalis, T Das, A Helmy