Neuroscience at Cambridge can be conceptualised in terms of six core themes. These groupings extend beyond the boundaries of traditional Departmental structures, providing an important focus for neuroscience research, and enabling the sharing of methodologies, technologies and conceptual issues. They support existing collaborations as well as inspiring new ones across the breadth of neuroscience in Cambridge. As these over-arching themes develop, the work within them will benefit from key strengths in Cambridge: first class researchers from a wide range of and expertise working in everything from biomedicine and maths, to psychiatry and philosophy, education, engineering and economics. Connections and overlap exist between all the six core themes, highlighting the inter-disciplinarity of Cambridge Neuroscience.