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  • Medicine
  • Research Focus


  • Clinical Neurosciences
  • Clinical Conditions

  • Cognitive impairment
  • Traumatic brain injury
  • Equipment & Techniques

  • Magnetic resonance imaging (MRI)
  • Neuropsychological testing
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    Anne Manktelow

    University Position
    Research Assistant


    I work part-time in the Division of Anaesthesia as a Research Assistant conducting the follow-up studies with patients recovering from traumatic brain injury (including MRI scanning and neuropsychological testing). I am also undertaking a part-time PhD within the department. The focus of my research will be the examination of the functional connectivity within the Default Mode Network post traumatic brain injury using resting state fMRI. We are comparing the alterations in this key resting state network between healthy controls and patients recovering from severe traumatic brain injury. We want to investigate how the brain compensates for loss of function due to the damage inflicted by the injury and explore the evidence for neural plasticity in the functional and structural connectivity analysis conducted on the TBI patients.

    Key Publications

    Working Memory after Traumatic Brain Injury: The Neural Basis of Improved Performance with Mwthylphenidate

    Journal: Frontiers in Behavioural Neuroscience
    Year: 2017
    Authors: Manktelow AE, Menon DK, Sahakian BJ, Stamatakis EA


    Methylphenidate-mediated motor control network enhancement in patients with traumatic brain injury.

    Journal: Brain Inj
    E-pub date: 1 Aug 2018
    Authors: CL Dorer, AE Manktelow, J Allanson, BJ Sahakian, JD Pickard, A Bateman, DK Menon, EA Stamatakis

    Spectral Diversity in Default Mode Network Connectivity Reflects Behavioral State.

    Journal: J Cogn Neurosci
    E-pub date: 1 Apr 2018
    Authors: MM Craig, AE Manktelow, BJ Sahakian, DK Menon, EA Stamatakis

    Anything goes? Regulation of the neural processes underlying response inhibition in TBI patients.

    Journal: Eur Neuropsychopharmacol
    E-pub date: 1 Feb 2017
    Authors: L Moreno-López, AE Manktelow, BJ Sahakian, DK Menon, EA Stamatakis

    Angular default mode network connectivity across working memory load.

    Journal: Hum Brain Mapp
    E-pub date: 1 Jan 2017
    Authors: D Vatansever, AE Manktelow, BJ Sahakian, DK Menon, EA Stamatakis

    Depression following traumatic brain injury: A functional connectivity perspective.

    Journal: Brain Inj
    E-pub date: 1 Aug 2016
    Authors: L Moreno-López, BJ Sahakian, A Manktelow, DK Menon, EA Stamatakis

    Cognitive Flexibility: A Default Network and Basal Ganglia Connectivity Perspective.

    Journal: Brain Connect
    E-pub date: 1 Apr 2016
    Authors: D Vatansever, AE Manktelow, BJ Sahakian, DK Menon, EA Stamatakis

    Dynamic Changes in White Matter Abnormalities Correlate With Late Improvement and Deterioration Following TBI: A Diffusion Tensor Imaging Study.

    Journal: Neurorehabil Neural Repair
    E-pub date: 1 Jan 2016
    Authors: VFJ Newcombe, MM Correia, C Ledig, MG Abate, JG Outtrim, D Chatfield, T Geeraerts, AE Manktelow, E Garyfallidis, JD Pickard, BJ Sahakian, PJA Hutchinson, D Rueckert, JP Coles, GB Williams, DK Menon

    Default Mode Dynamics for Global Functional Integration.

    Journal: J Neurosci
    E-pub date: 18 Nov 2015
    Authors: D Vatansever, DK Menon, AE Manktelow, BJ Sahakian, EA Stamatakis

    Default mode network connectivity during task execution.

    Journal: Neuroimage
    E-pub date: 15 Nov 2015
    Authors: D Vatansever, DK Menon, AE Manktelow, BJ Sahakian, EA Stamatakis

    Microstructural basis of contusion expansion in traumatic brain injury: insights from diffusion tensor imaging.

    Journal: Journal of Cerebral Blood Flow and Metabolism
    E-pub date: 1 Jun 2013
    Authors: VFJ Newcombe, GB Williams, JG Outtrim, D Chatfield, M Gulia Abate, T Geeraerts, A Manktelow, H Room, L Mariappen, PJ Hutchinson, JP Coles, DK Menon

    Critical thresholds for cerebrovascular reactivity after traumatic brain injury.

    Journal: Neurocrit Care
    E-pub date: 1 Apr 2012
    Authors: E Sorrentino, J Diedler, M Kasprowicz, KP Budohoski, C Haubrich, P Smielewski, JG Outtrim, A Manktelow, PJ Hutchinson, JD Pickard, DK Menon, M Czosnyka