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  • Psychiatry
    • Research Theme Beyond the Neuron Adaptive Brain Computations
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    Dr Benjamin Perry

    University Position
    Clinical Lecturer

    Interests

    I am a Clinical Lecturer in the Department of Psychiatry, and a Higher Trainee in General Psychiatry in Cambridgeshire and Peterborough NHS Foundation Trust. I recently completed an NIHR Doctoral Research Fellowship in the Department. I'm interested in the associations of cardiometabolic and mental disorders, primarily schizophrenia and depression. I'm particularly interested in prognosis research and risk prediction, and during my PhD developed the Psychosis Metabolic Risk Calculator (PsyMetRiC) - a cardiometabolic risk prediction algorithm for young people with psychosis. In addition, through the use of population-level and genetic data, my work has sought to explore shared biological mechanisms for comorbid cardiometabolic and mental disorders.

    Key Publications

    Predicting treatment resistance from first-episode psychosis using routinely collected clinical information.

    DOI: http://doi.org/10.1038/s44220-022-00001-z
    Journal: Nat Ment Health
    E-pub date: 19 Jan 2023
    Authors: EF Osimo, BI Perry, P Mallikarjun, M Pritchard, J Lewis, A Katunda, GK Murray, J Perez, PB Jones, RN Cardinal, OD Howes, R Upthegrove, GM Khandaker

    Adipose tissue dysfunction, inflammation, and insulin resistance: alternative pathways to cardiac remodelling in schizophrenia. A multimodal, case-control study.

    DOI: http://doi.org/10.1038/s41398-021-01741-9
    Journal: Transl Psychiatry
    E-pub date: 6 Dec 2021
    Authors: EF Osimo, M Sweeney, A de Marvao, A Berry, B Statton, BI Perry, T Pillinger, T Whitehurst, SA Cook, DP O'Regan, EL Thomas, OD Howes

    Development and external validation of the Psychosis Metabolic Risk Calculator (PsyMetRiC): a cardiometabolic risk prediction algorithm for young people with psychosis.

    DOI: http://doi.org/10.1016/S2215-0366(21)00114-0
    Journal: Lancet Psychiatry
    E-pub date: 1 Jul 2021
    Authors: BI Perry, EF Osimo, R Upthegrove, PK Mallikarjun, J Yorke, J Stochl, J Perez, S Zammit, O Howes, PB Jones, GM Khandaker

    Publications

    Contribution of severe mental disorders to fatally harmful effects of physical disorders: national cohort study.

    DOI: http://doi.org/10.1192/bjp.2024.110
    Journal: Br J Psychiatry
    E-pub date: 1 Oct 2024
    Authors: T Formánek, D Krupchanka, BI Perry, K Mladá, EF Osimo, J Masopust, PB Jones, O Plana-Ripoll

    Associations of 2,922 genetically predicted plasma protein levels with mental illness and response to treatment

    DOI: http://doi.org/10.21203/rs.3.rs-4313341/v1
    Journal:
    E-pub date: 1 Aug 2024
    Authors: K Zhang, B Chidiac, V Zhao, S Noordeen, V Warrier, A Butterworth, BI Perry, GK Murray, EF Osimo

    More must be done to reduce cardiovascular risk for patients on antipsychotic medications.

    DOI: http://doi.org/10.1097/YIC.0000000000000464
    Journal: Int Clin Psychopharmacol
    E-pub date: 1 May 2023
    Authors: EF Osimo, BI Perry, GK Murray

    The psychosis metabolic risk calculator (PsyMetRiC) for young people with psychosis: International external validation and site-specific recalibration in two independent European samples.

    DOI: http://doi.org/10.1016/j.lanepe.2022.100493
    Journal: Lancet Reg Health Eur
    E-pub date: 1 Nov 2022
    Authors: BI Perry, F Vandenberghe, N Garrido-Torres, EF Osimo, M Piras, J Vazquez-Bourgon, R Upthegrove, C Grosu, VO-G De La Foz, PB Jones, N Laaboub, M Ruiz-Veguilla, J Stochl, C Dubath, M Canal-Rivero, P Mallikarjun, A Delacrétaz, N Ansermot, E Fernandez-Egea, S Crettol, F Gamma, KJ Plessen, P Conus, GM Khandaker, GK Murray, CB Eap, B Crespo-Facorro

    Risk Prediction in Psychosis: Progress Made and Challenges Ahead.

    DOI: http://doi.org/10.1016/j.biopsych.2021.08.015
    Journal: Biol Psychiatry
    E-pub date: 1 Nov 2021
    Authors: BI Perry, EF Osimo, GM Khandaker

    Longitudinal association between CRP levels and risk of psychosis: a meta-analysis of population-based cohort studies.

    DOI: http://doi.org/10.1038/s41537-021-00161-4
    Journal: NPJ Schizophr
    E-pub date: 28 May 2021
    Authors: EF Osimo, L Baxter, J Stochl, BI Perry, SA Metcalf, SK Kunutsor, JA Laukkanen, MK Wium-Andersen, PB Jones, GM Khandaker

    Inflammatory and cardiometabolic markers at presentation with first episode psychosis and long-term clinical outcomes: A longitudinal study using electronic health records.

    DOI: http://doi.org/10.1016/j.bbi.2020.09.011
    Journal: Brain Behav Immun
    E-pub date: 1 Jan 2021
    Authors: EF Osimo, BI Perry, RN Cardinal, M-E Lynall, J Lewis, A Kudchadkar, GK Murray, J Perez, PB Jones, GM Khandaker