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Department
  • Psychiatry
    • Research Theme Lifelong Brain Development and Brain Ageing

    Other Interdiciplinary Incentives

  • Public Health

    • Research Focus

    Keywords

  • Ageing
  • Alzheimer's Disease
  • Cognitive Ageing
  • Epidemiology

    • Clinical Conditions

  • Alzheimer's disease
  • Cognitive impairment
  • Dementia

    • Equipment & Techniques

  • Other

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    Professor Carol Brayne

    University Position
    Professor

    Interests

    My research programme is based around longitudinal population based studies of people aged 65 and above, running since 1985. They include collections of blood, and are linked to the Cambridge Brain Bank. Opportunities exist for translation from lab to population, as well as traditional neuroscience studies.

    Key Publications

    Neural Contributions to Reduced Fluid Intelligence across the Adult Lifespan.

    DOI: http://doi.org/10.1523/JNEUROSCI.0148-22.2022
    Journal: J Neurosci
    E-pub date: 11 Jan 2023
    Authors: DJ Mitchell, ALS Mousley, MA Shafto, Cam-CAN, J Duncan

    The CamPaIGN study of Parkinson’s disease: 10-year outlook in an incident population-based cohort.

    DOI: http://doi.org/10.1136/jnnp-2013-305277
    Journal: J Neurol Neurosurg Psychiatry
    E-pub date: 1 Nov 2013
    Authors: CH Williams-Gray, SL Mason, JR Evans, T Foltynie, C Brayne, TW Robbins, RA Barker

    The distinct cognitive syndromes of Parkinson’s disease: 5 year follow-up of the CamPaIGN cohort.

    DOI: http://doi.org/10.1093/brain/awp245
    Journal: Brain
    E-pub date: 1 Nov 2009
    Authors: CH Williams-Gray, JR Evans, A Goris, T Foltynie, M Ban, TW Robbins, C Brayne, BS Kolachana, DR Weinberger, SJ Sawcer, RA Barker

    Evolution of cognitive dysfunction in an incident Parkinson’s disease cohort.

    DOI: http://doi.org/10.1093/brain/awm111
    Journal: Brain
    E-pub date: 1 Jul 2007
    Authors: CH Williams-Gray, T Foltynie, CEG Brayne, TW Robbins, RA Barker

    Publications

    Temporal trends in population attributable fractions of modifiable risk factors for dementia: a time-series study of the English Longitudinal Study of Ageing (2004–2019)

    DOI: http://doi.org/10.1186/s12916-024-03464-2
    Journal: BMC Med
    E-pub date: 26 Jun 2024
    Authors: S Chen, BR Underwood, RN Cardinal, X Chen, S Chen, J Amin, H Jin, J Huang, C Mueller, LL Yan, C Brayne, H Kuper

    Factors That Influence Meeting the Recommended Weekly Physical Activity Target Among Older People With Physical Multimorbidity: Evidence From 6 Low- and Middle-Income Countries.

    DOI: http://doi.org/10.1123/jpah.2023-0473
    Journal: J Phys Act Health
    E-pub date: 1 Mar 2024
    Authors: L Smith, DK Yon, L Butler, K Kostev, C Brayne, Y Barnett, BR Underwood, JI Shin, M Rahmati, SAS Neufeld, A Ragnhildstveit, GF López Sánchez, A Koyanagi

    Relationship between severe mental illness and physical multimorbidity: a meta-analysis and call for action.

    DOI: http://doi.org/10.1136/bmjment-2023-300870
    Journal: BMJ Ment Health
    E-pub date: 1 Oct 2023
    Authors: D Pizzol, M Trott, L Butler, Y Barnett, T Ford, SA Neufeld, A Ragnhildstveit, CN Parris, BR Underwood, GF López Sánchez, M Fossey, C Brayne, E Fernandez-Egea, G Fond, L Boyer, JI Shin, S Pardhan, L Smith

    Autism and education—The role of Europeanisation in South-Eastern Europe: Policy mapping in Bulgaria, Romania and Croatia

    DOI: http://doi.org/10.1111/chso.12632
    Journal: Children and Society
    E-pub date: 1 Sep 2023
    Authors: R van Kessel, A Massrali, P Vom Felde Genannt Imbusch, A Dragu, C Brayne, S Baron-Cohen, K Czabanowska, A Roman-Urrestarazu

    Autism incidence and spatial analysis in more than 7 million pupils in English schools: a retrospective, longitudinal, school registry study.

    DOI: http://doi.org/10.1016/S2352-4642(22)00247-4
    Journal: Lancet Child Adolesc Health
    E-pub date: 1 Dec 2022
    Authors: A Roman-Urrestarazu, JC Yang, R van Kessel, V Warrier, G Dumas, H Jongsma, G Gatica-Bahamonde, C Allison, FE Matthews, S Baron-Cohen, C Brayne

    Education and austerity in the European Union from an autism perspective: Policy mapping in Ireland, Portugal, Italy, and Greece

    DOI: http://doi.org/10.1002/epa2.1121
    Journal: European Policy Analysis
    E-pub date: 1 Nov 2021
    Authors: R van Kessel, I Siepmann, L Capucha, AK Paschalis, C Brayne, S Baron-Cohen, K Czabanowska, A Roman-Urrestarazu

    Modifiable risk factors for dementia and dementia risk profiling. A user manual for Brain Health Services-part 2 of 6.

    DOI: http://doi.org/10.1186/s13195-021-00895-4
    Journal: Alzheimers Res Ther
    E-pub date: 11 Oct 2021
    Authors: JM Ranson, T Rittman, S Hayat, C Brayne, F Jessen, K Blennow, C van Duijn, F Barkhof, E Tang, CJ Mummery, BCM Stephan, D Altomare, GB Frisoni, F Ribaldi, JL Molinuevo, P Scheltens, DJ Llewellyn, European Task Force for Brain Health Services

    Quantitative Checklist for Autism in Toddlers (Q-CHAT). A population screening study with follow-up: the case for multiple time-point screening for autism.

    DOI: http://doi.org/10.1136/bmjpo-2020-000700
    Journal: BMJ Paediatr Open
    E-pub date: 1 Aug 2021
    Authors: C Allison, FE Matthews, L Ruta, G Pasco, R Soufer, C Brayne, T Charman, S Baron-Cohen

    Association of Race/Ethnicity and Social Disadvantage With Autism Prevalence in 7 Million School Children in England.

    DOI: http://doi.org/10.1001/jamapediatrics.2021.0054
    Journal: JAMA Pediatr
    E-pub date: 1 Jun 2021
    Authors: A Roman-Urrestarazu, R van Kessel, C Allison, FE Matthews, C Brayne, S Baron-Cohen

    Autism screening and conditional cash transfers in Chile: Using the Quantitative Checklist (Q-CHAT) for early autism detection in a low resource setting.

    DOI: http://doi.org/10.1177/1362361320972277
    Journal: Autism
    E-pub date: 1 May 2021
    Authors: A Roman-Urrestarazu, C Yáñez, C López-Garí, C Elgueta, C Allison, C Brayne, M Troncoso, S Baron-Cohen

    Inclusive education in the European Union: A fuzzy-set qualitative comparative analysis of education policy for autism.

    DOI: http://doi.org/10.1080/19371918.2021.1877590
    Journal: Soc Work Public Health
    E-pub date: 17 Feb 2021
    Authors: R van Kessel, R Hrzic, S Cassidy, C Brayne, S Baron-Cohen, K Czabanowska, A Roman-Urrestarazu

    Autism and education-international policy in small EU states: policy mapping in Malta, Cyprus, Luxembourg and Slovenia.

    DOI: http://doi.org/10.1093/eurpub/ckaa146
    Journal: Eur J Public Health
    E-pub date: 11 Dec 2020
    Authors: R van Kessel, R Hrzic, K Czabanowska, A Baranger, N Azzopardi-Muscat, N Charambalous-Darden, C Brayne, S Baron-Cohen, A Roman-Urrestarazu

    Autism and education-Teacher policy in Europe: Policy mapping of Austria, Hungary, Slovakia and Czech Republic.

    DOI: http://doi.org/10.1016/j.ridd.2020.103734
    Journal: Res Dev Disabil
    E-pub date: 1 Oct 2020
    Authors: R van Kessel, P Steinhoff, O Varga, D Breznoščáková, K Czabanowska, C Brayne, S Baron-Cohen, A Roman-Urrestarazu

    Education, Special Needs, and Autism in the Baltic States: Policy Mapping in Estonia, Latvia, and Lithuania

    DOI: http://doi.org/10.3389/feduc.2020.00161
    Journal: Frontiers in Education
    E-pub date: 4 Sep 2020
    Authors: R van Kessel, W Dijkstra, A Prasauskiene, A Villeruša, C Brayne, S Baron-Cohen, K Czabanowska, A Roman-Urrestarazu

    Quotas, and Anti-discrimination Policies Relating to Autism in the EU: Scoping Review and Policy Mapping in Germany, France, Netherlands, United Kingdom, Slovakia, Poland, and Romania.

    DOI: http://doi.org/10.1002/aur.2315
    Journal: Autism Res
    E-pub date: 31 Aug 2020
    Authors: D Bunt, R van Kessel, RA Hoekstra, K Czabanowska, C Brayne, S Baron-Cohen, A Roman-Urrestarazu

    Inclusive Education in the European Union: A Fuzzy-Set Qualitative Comparative Analysis of Education Policy for Autism

    DOI: http://doi.org/10.21203/rs.3.rs-36514/v1
    Journal:
    E-pub date: 1 Aug 2020
    Authors: RV Kessel, R Hrzic, S Cassidy, C Brayne, S Baron-Cohen, A Roman-Urrestarazu, K Czabanowska

    Perceptual and conceptual processing of visual objects across the adult lifespan.

    DOI: http://doi.org/10.1038/s41598-019-50254-5
    Journal: Sci Rep
    E-pub date: 24 Sep 2019
    Authors: R Bruffaerts, LK Tyler, M Shafto, KA Tsvetanov, Cambridge Centre for Ageing and Neuroscience, A Clarke

    Autism and family involvement in the right to education in the EU: policy mapping in the Netherlands, Belgium and Germany.

    DOI: http://doi.org/10.1186/s13229-019-0297-x
    Journal: Mol Autism
    E-pub date: 1 Aug 2019
    Authors: R van Kessel, A Roman-Urrestarazu, A Ruigrok, R Holt, M Commers, RA Hoekstra, K Czabanowska, C Brayne, S Baron-Cohen

    Autism and the right to education in the EU: policy mapping and scoping review of Nordic countries Denmark, Finland, and Sweden.

    DOI: http://doi.org/10.1186/s13229-019-0290-4
    Journal: Mol Autism
    E-pub date: 1 Aug 2019
    Authors: R van Kessel, S Walsh, ANV Ruigrok, R Holt, A Yliherva, E Kärnä, I Moilanen, E Hjörne, ST Johansson, D Schendel, L Pedersen, M Jørgensen, C Brayne, S Baron-Cohen, A Roman-Urrestarazu

    Autism prevalence in China is comparable to Western prevalence.

    DOI: http://doi.org/10.1186/s13229-018-0246-0
    Journal: Mol Autism
    E-pub date: 1 Aug 2019
    Authors: X Sun, C Allison, L Wei, FE Matthews, B Auyeung, YY Wu, S Griffiths, J Zhang, S Baron-Cohen, C Brayne

    Prediction of cognition in Parkinson’s disease with a clinical-genetic score: a longitudinal analysis of nine cohorts.

    DOI: http://doi.org/10.1016/S1474-4422(17)30122-9
    Journal: Lancet Neurol
    E-pub date: 31 Aug 2017
    Authors: G Liu, JJ Locascio, J-C Corvol, B Boot, Z Liao, K Page, D Franco, K Burke, IE Jansen, A Trisini-Lipsanopoulos, S Winder-Rhodes, CM Tanner, AE Lang, S Eberly, A Elbaz, A Brice, G Mangone, B Ravina, I Shoulson, F Cormier-Dequaire, P Heutink, JJ van Hilten, RA Barker, CH Williams-Gray, J Marinus, CR Scherzer, HBS, CamPaIGN, PICNICS, PROPARK, PSG, DIGPD, PDBP

    Comparative epidemiology of incident Parkinson’s disease in Cambridgeshire, UK.

    DOI: http://doi.org/10.1136/jnnp-2015-312581
    Journal: J Neurol Neurosurg Psychiatry
    E-pub date: 1 Sep 2016
    Authors: JR Evans, G Cummins, DP Breen, T Foltynie, SL Mason, CEG Brayne, CH Williams-Gray, RA Barker

    Validation of existing diagnosis of autism in mainland China using standardised diagnostic instruments.

    DOI: http://doi.org/10.1177/1362361314556785
    Journal: Autism
    E-pub date: 1 Nov 2015
    Authors: X Sun, C Allison, B Auyeung, Z Zhang, FE Matthews, S Baron-Cohen, C Brayne

    Exploring the Underdiagnosis and Prevalence of Autism Spectrum Conditions in Beijing.

    DOI: http://doi.org/10.1002/aur.1441
    Journal: Autism Research
    E-pub date: 1 Jun 2015
    Authors: X Sun, C Allison, FE Matthews, Z Zhang, B Auyeung, S Baron-Cohen, C Brayne

    Distinct aspects of frontal lobe structure mediate age-related differences in fluid intelligence and multitasking.

    DOI: http://doi.org/10.1038/ncomms6658
    Journal: Nat Commun
    E-pub date: 18 Dec 2014
    Authors: RA Kievit, SW Davis, DJ Mitchell, JR Taylor, J Duncan, Cam-CAN Research Team, RNA Henson, Cam-CAN Research Team

    Parental concerns, socioeconomic status, and the risk of autism spectrum conditions in a population-based study.

    DOI: http://doi.org/10.1016/j.ridd.2014.07.037
    Journal: Res Dev Disabil
    E-pub date: 1 Dec 2014
    Authors: X Sun, C Allison, B Auyeung, S Baron-Cohen, C Brayne

    Comparison between a Mandarin Chinese version of the Childhood Autism Spectrum Test and the Clancy Autism Behaviour Scale in mainland China.

    DOI: http://doi.org/10.1016/j.ridd.2014.02.005
    Journal: Res Dev Disabil
    E-pub date: 1 Jul 2014
    Authors: X Sun, C Allison, B Auyeung, FE Matthews, Z Zhang, S Baron-Cohen, C Brayne

    Psychometric properties of the Mandarin version of the Childhood Autism Spectrum Test (CAST): an exploratory study.

    DOI: http://doi.org/10.1007/s10803-013-2024-3
    Journal: Journal of Autism and Developmental Disorders
    E-pub date: 1 Jan 2014
    Authors: X Sun, C Allison, B Auyeung, FE Matthews, S Norton, S Baron-Cohen, C Brayne

    The Mandarin Childhood Autism Spectrum Test (CAST): sex differences.

    DOI: http://doi.org/10.1007/s10803-014-2088-8
    Journal: Journal of Autism and Developmental Disorders
    E-pub date: 1 Jan 2014
    Authors: X Sun, C Allison, B Auyeung, FE Matthews, SJ Sharp, S Baron-Cohen, C Brayne

    Service provision for autism in mainland China: preliminary mapping of service pathways.

    DOI: http://doi.org/10.1016/j.socscimed.2013.08.016
    Journal: Soc Sci Med
    E-pub date: 1 Dec 2013
    Authors: X Sun, C Allison, B Auyeung, FE Matthews, S Baron-Cohen, C Brayne

    The Mandarin Chinese version of the childhood autism spectrum test (CAST): test-retest reliability.

    DOI: http://doi.org/10.1016/j.ridd.2013.05.042
    Journal: Res Dev Disabil
    E-pub date: 1 Oct 2013
    Authors: X Sun, C Allison, B Auyeung, FE Matthews, S Baron-Cohen, C Brayne

    From molecule to clinic and community for neurodegeneration: research to bridge translational gaps.

    DOI: http://doi.org/10.3233/JAD-2012-129006
    Journal: J Alzheimers Dis
    E-pub date: 1 Aug 2013
    Authors: C Brayne, RA Barker, D Harold, PG Ince, GM Savva, J Williams, CH Williams-Gray, SB Wharton

    Prevalence of autism in mainland China, Hong Kong and Taiwan: a systematic review and meta-analysis.

    DOI: http://doi.org/10.1186/2040-2392-4-7
    Journal: Mol Autism
    E-pub date: 9 Apr 2013
    Authors: X Sun, C Allison, FE Matthews, SJ Sharp, B Auyeung, S Baron-Cohen, C Brayne

    What is available for case identification in autism research in mainland China?

    DOI: http://doi.org/10.1016/j.rasd.2012.11.003
    Journal: Research in Autism Spectrum Disorders
    E-pub date: 15 Mar 2013
    Authors: X Sun, C Allison, B Auyeung, FE Matthews, S Baron-Cohen, C Brayne

    Service provision for autism in mainland China: a service providers’ perspective.

    DOI: http://doi.org/10.1016/j.ridd.2012.08.010
    Journal: Res Dev Disabil
    E-pub date: 1 Jan 2013
    Authors: X Sun, C Allison, B Auyeung, FE Matthews, S Murray, S Baron-Cohen, C Brayne

    A review of healthcare service and education provision of Autism Spectrum Condition in mainland China.

    DOI: http://doi.org/10.1016/j.ridd.2012.08.013
    Journal: Res Dev Disabil
    E-pub date: 1 Jan 2013
    Authors: X Sun, C Allison, B Auyeung, S Baron-Cohen, C Brayne

    From molecule to clinic and community for neurodegeneration: Research to bridge translational gaps

    DOI: http://doi.org/10.3233/978-1-61499-154-0-385
    Journal: Advances in Alzheimer's Disease
    E-pub date: 1 Dec 2012
    Authors: C Brayne, RA Barker, D Harold, PG Ince, GM Savva, J Williams, CH Williams-Gray, SB Wharton

    Are autism spectrum conditions more prevalent in an information-technology region? A school-based study of three regions in the Netherlands.

    DOI: http://doi.org/10.1007/s10803-011-1302-1
    Journal: Journal of Autism and Developmental Disorders
    E-pub date: 1 May 2012
    Authors: MT Roelfsema, RA Hoekstra, C Allison, S Wheelwright, C Brayne, FE Matthews, S Baron-Cohen

    The natural history of treated Parkinson’s disease in an incident, community based cohort.

    DOI: http://doi.org/10.1136/jnnp.2011.240366
    Journal: J Neurol Neurosurg Psychiatry
    E-pub date: 1 Oct 2011
    Authors: JR Evans, SL Mason, CH Williams-Gray, T Foltynie, C Brayne, TW Robbins, RA Barker

    No major effect of twinning on autistic traits.

    DOI: http://doi.org/10.1002/aur.207
    Journal: Autism Res
    E-pub date: 1 Oct 2011
    Authors: S Curran, K Dworzynski, F Happé, A Ronald, C Allison, S Baron-Cohen, C Brayne, PF Bolton

    Prevalence of autism-spectrum conditions: UK school-based population study.

    DOI: http://doi.org/10.1192/bjp.bp.108.059345
    Journal: Br J Psychiatry
    E-pub date: 1 Jun 2009
    Authors: S Baron-Cohen, FJ Scott, C Allison, J Williams, P Bolton, FE Matthews, C Brayne

    The Childhood Autism Spectrum Test (CAST): sex differences.

    DOI: http://doi.org/10.1007/s10803-008-0558-6
    Journal: J Autism Dev Disord
    E-pub date: 1 Oct 2008
    Authors: JG Williams, C Allison, FJ Scott, PF Bolton, S Baron-Cohen, FE Matthews, C Brayne

    The Q-CHAT (Quantitative CHecklist for Autism in Toddlers): a normally distributed quantitative measure of autistic traits at 18-24 months of age: preliminary report.

    DOI: http://doi.org/10.1007/s10803-007-0509-7
    Journal: J Autism Dev Disord
    E-pub date: 1 Sep 2008
    Authors: C Allison, S Baron-Cohen, S Wheelwright, T Charman, J Richler, G Pasco, C Brayne

    The Childhood Asperger Syndrome Test (CAST): test-retest reliability in a high scoring sample.

    DOI: http://doi.org/10.1177/1362361307075710
    Journal: Autism
    E-pub date: 1 Mar 2007
    Authors: C Allison, J Williams, F Scott, C Stott, P Bolton, S Baron-Cohen, C Brayne

    The Childhood Asperger Syndrome Test (CAST): test-retest reliability.

    DOI: http://doi.org/10.1177/1362361306066612
    Journal: Autism
    E-pub date: 1 Jul 2006
    Authors: J Williams, C Allison, F Scott, C Stott, P Bolton, S Baron-Cohen, C Brayne

    The CAST (Childhood Asperger Syndrome Test): test accuracy.

    DOI: http://doi.org/10.1177/1362361305049029
    Journal: Autism
    E-pub date: 1 Feb 2005
    Authors: J Williams, F Scott, C Stott, C Allison, P Bolton, S Baron-Cohen, C Brayne

    The CAST (Childhood Asperger and Syndrome Test) – Test accuracy

    DOI: http://doi.org/10.1177/136261305049029
    Journal: AUTISM
    E-pub date: 1 Feb 2005
    Authors: J Williams, F Scott, C Stott, C Allison, P Bolton, S Baron-Cohen, C Brayne

    Brief report: prevalence of autism spectrum conditions in children aged 5-11 years in Cambridgeshire, UK.

    DOI: http://doi.org/10.1177/1362361302006003002
    Journal: Autism
    E-pub date: 1 Sep 2002
    Authors: FJ Scott, S Baron-Cohen, P Bolton, C Brayne

    The CAST (Childhood Asperger Syndrome Test): preliminary development of a UK screen for mainstream primary-school-age children.

    DOI: http://doi.org/10.1177/1362361302006001003
    Journal: Autism
    E-pub date: 1 Mar 2002
    Authors: FJ Scott, S Baron-Cohen, P Bolton, C Brayne