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Research Theme Beyond the Neuron
Research Focus

Keywords

  • Stem Cells
  • Clinical Conditions

  • Alzheimer's disease
  • Multiple sclerosis
  • Schizophrenia
  • Equipment & Techniques

  • Cell culture
  • Confocal microscopy
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    Dr Balazs Varga

    (he/him/his)
    University Position
    Research Associate
    Dr Balazs Varga is pleased to consider applications from prospective PhD students.

    Interests

    Research scientist working on understanding the development and physiology of the human brain and its dysfunction in disease conditions using cutting-edge bio-engineering, biotechnology, genetic tools and stem cell biology.

    Key Publications

    Signal requirement for cortical potential of transplantable human neuroepithelial stem cells.

    DOI: http://doi.org/10.1038/s41467-022-29839-8
    Journal: Nat Commun
    E-pub date: 23 May 2022
    Authors: BV Varga, M Faiz, H Pivonkova, G Khelifi, H Yang, S Gao, E Linderoth, M Zhen, RT Karadottir, SM Hussein, A Nagy

    Publications

    iPS-cell-derived microglia promote brain organoid maturation via cholesterol transfer.

    DOI: http://doi.org/10.1038/s41586-023-06713-1
    Journal: Nature
    E-pub date: 1 Nov 2023
    Authors: DS Park, T Kozaki, SK Tiwari, M Moreira, A Khalilnezhad, F Torta, N Olivié, CH Thiam, O Liani, A Silvin, WW Phoo, L Gao, A Triebl, WK Tham, L Gonçalves, WT Kong, S Raman, XM Zhang, G Dunsmore, CA Dutertre, S Lee, JM Ong, A Balachander, S Khalilnezhad, J Lum, K Duan, ZM Lim, L Tan, I Low, KH Utami, XY Yeo, S Di Tommaso, J-W Dupuy, B Varga, RT Karadottir, MC Madathummal, I Bonne, B Malleret, ZY Binte, N Wei Da, Y Tan, WJ Wong, J Zhang, J Chen, RM Sobota, SW Howland, LG Ng, F Saltel, D Castel, J Grill, V Minard, S Albani, JKY Chan, MS Thion, SY Jung, MR Wenk, MA Pouladi, C Pasqualini, V Angeli, ONF Cexus, F Ginhoux

    Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer’s disease via MFG-E8.

    DOI: http://doi.org/10.1016/j.xcrm.2023.101175
    Journal: Cell Rep Med
    E-pub date: 19 Sep 2023
    Authors: M Tzioras, MJD Daniels, C Davies, P Baxter, D King, S McKay, B Varga, K Popovic, M Hernandez, AJ Stevenson, J Barrington, E Drinkwater, J Borella, RK Holloway, J Tulloch, J Moss, C Latta, J Kandasamy, D Sokol, C Smith, VE Miron, RT Káradóttir, GE Hardingham, CM Henstridge, PM Brennan, BW McColl, TL Spires-Jones

    Electrochemically induced in vitro focal hypoxia in human neurons.

    DOI: http://doi.org/10.3389/fcell.2022.968341
    Journal: Front Cell Dev Biol
    E-pub date: 1 Aug 2022
    Authors: JJY Wong, BV Varga, RT Káradóttir, EAH Hall

    Periods of synchronized myelin changes shape brain function and plasticity.

    DOI: http://doi.org/10.1038/s41593-021-00917-2
    Journal: Nat Neurosci
    E-pub date: 1 Nov 2021
    Authors: O de Faria, H Pivonkova, B Varga, S Timmler, KA Evans, RT Káradóttir

    Synaptic Dysfunction in Human Neurons With Autism-Associated Deletions in PTCHD1-AS.

    DOI: http://doi.org/10.1016/j.biopsych.2019.07.014
    Journal: Biol Psychiatry
    E-pub date: 15 Jan 2020
    Authors: PJ Ross, W-B Zhang, RSF Mok, K Zaslavsky, E Deneault, L D'Abate, DC Rodrigues, RKC Yuen, M Faheem, M Mufteev, A Piekna, W Wei, P Pasceri, RJ Landa, A Nagy, B Varga, MW Salter, SW Scherer, J Ellis