• Biochemistry
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    Professor Kevin Brindle

    University Position


    We have developed non-invasive magnetic resonance imaging (MRI) techniques that enable us to track labelled cells that have been implanted in the CNS. This work has been conducted in collaboration with Robin Franklin. In addition we are developing a gene reporter construct for MRI, that can be used in conjunction with our cell labelling techniques. Thus, following stem cell transplantation into the CNS, we should be able to tell not only where the cells are but also whether they have differentiated.

    Key Publications


    Quantifying normal human brain metabolism using hyperpolarized [1-13C]pyruvate and magnetic resonance imaging.

    Journal: Neuroimage
    E-pub date: 1 Apr 2019
    Authors: JT Grist, MA McLean, F Riemer, RF Schulte, SS Deen, F Zaccagna, R Woitek, CJ Daniels, JD Kaggie, T Matys, I Patterson, R Slough, AB Gill, A Chhabra, R Eichenberger, M-C Laurent, A Comment, JH Gillard, AJ Coles, DJ Tyler, I Wilkinson, B Basu, DJ Lomas, MJ Graves, KM Brindle, FA Gallagher