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College Wolfson College
Department
  • Engineering
  • School
  • Technology
  • Research Focus

    Keywords

  • Brain Machine Interfaces
  • Neuroengineering
  • Clinical Conditions

  • Parkinson's disease
  • Equipment & Techniques

  • Cell culture
  • Electrophysiological recording techniques
  • Computational modelling
  • Fluorescence microscopy
  • Immunohistochemistry
  • Science Culture

  • Widening Participation
  • Open Access
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    Elle Richardson

    (she/her/hers)
    University Position
    PhD student

    Interests

    My doctoral research aims to engineer a new therapy for Parkinson’s disease: a biohybrid medical device that combines stem cell therapy with microelectrodes. The device is designed not only to regenerate neural circuits damaged by Parkinson’s but also to restore their function. This work is crucial because current treatments, such as deep brain stimulation, only alleviate symptoms, while pioneering stem cell therapies struggle to survive and integrate into the brain, limiting their regenerative potential. By developing this biohybrid device and optimising the survival and integration of therapeutic cells within existing networks, I aim to help engineer the next generation of Parkinson’s therapeutics.

    Key Publications

    Evergene: an interactive webtool for large-scale gene-centric analysis of primary tumours

    DOI: https://doi.org/10.1093/bioadv/vbae092
    Journal: Bioinformatics Advances | Oxford Academic
    Year: 2024
    Authors: Anna Kennedy, Ella Richardson, Jonathan Higham, Panagiotis Kotsantis, Richard Mort, Barbara Bo-Ju Shih

    Publications