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    Dr George Savulich

    University Position
    Research Associate

    Interests

    Cognitive enhancement in neuropsychiatric disorders and in healthy people; the impact of technology on older age mental health; the effects of novel psychoactive substances on cognition and emotion; and information-processing biases in psychosis.

    Key Publications

    Publications

    Chronic escitalopram in healthy volunteers has specific effects on reinforcement sensitivity: a double-blind, placebo-controlled semi-randomised study.

    DOI: http://doi.org/10.1038/s41386-022-01523-x
    Journal: Neuropsychopharmacology
    E-pub date: 1 Mar 2023
    Authors: C Langley, S Armand, Q Luo, G Savulich, T Segerberg, A Søndergaard, EB Pedersen, N Svart, O Overgaard-Hansen, A Johansen, C Borgsted, RN Cardinal, TW Robbins, DS Stenbæk, GM Knudsen, BJ Sahakian

    The ‘Resilient Brain’: challenging key characteristics associated with the concept of resilience.

    DOI: http://doi.org/10.1017/S0033291722003907
    Journal: Psychol Med
    E-pub date: 25 Jan 2023
    Authors: G Savulich, E Ferry-Bolder, TV Lim, E Mak, KD Ersche

    Synaptic loss in behavioural variant frontotemporal dementia revealed by [11C]UCB-J PET

    DOI: http://doi.org/10.1101/2022.01.30.22270123
    Journal:
    E-pub date: 1 Aug 2022
    Authors: M Malpetti, S Jones, T Cope, N Holland, M Naessens, M Rouse, G Savulich, T Fryer, Y Hong, SM Sephton, F Aigbirhio, J O’Brien, J Rowe

    Molecular pathology and synaptic loss in primary tauopathies: A [18F]AV-1451 and [11C]UCB-J PET study

    DOI: http://doi.org/10.1093/brain/awab282
    Journal: Brain
    E-pub date: 29 Mar 2022
    Authors: N Holland, M Malpetti, T Rittman, E Mak, L Passamonti, S Kaalund, F Hezemans, P Jones, G Savulich, Y Hong, T Fryer, F Aigbirhio, J O'Brien, J Rowe

    [18F]-AV-1451 binding in the substantia nigra as a marker of neuromelanin in Lewy body diseases.

    DOI: http://doi.org/10.1093/braincomms/fcab177
    Journal: Brain Commun
    E-pub date: 1 Aug 2021
    Authors: E Mak, A Kouli, N Holland, N Nicastro, G Savulich, A Surendranathan, M Malpetti, R Manavaki, YT Hong, TD Fryer, F Aigbirhio, JB Rowe, JT O'Brien, CH Williams-Gray

    In vivo coupling of dendritic complexity with presynaptic density in primary tauopathies.

    DOI: http://doi.org/10.1016/j.neurobiolaging.2021.01.016
    Journal: Neurobiol Aging
    E-pub date: 1 May 2021
    Authors: E Mak, N Holland, PS Jones, G Savulich, A Low, M Malpetti, SS Kaalund, L Passamonti, T Rittman, R Romero-Garcia, R Manavaki, GB Williams, YT Hong, TD Fryer, FI Aigbirhio, JT O'Brien, JB Rowe

    In vivo coupling of dendritic complexity with presynaptic density in primary tauopathies

    DOI: http://doi.org/10.1101/2020.12.24.20248838
    Journal:
    E-pub date: 1 Aug 2020
    Authors: E Mak, N Holland, S Jones, G Savulich, A Low, M Malpetti, S Kaalund, L Passamonti, T Rittman, R Romero-Garcia, R Manavaki, G Williams, Y Hong, T Fryer, F Aigbirhio, J O’Brien, J Rowe

    Synaptic loss in primary tauopathies revealed by [11C]UCB-J positron emission tomography

    DOI: http://doi.org/10.1101/2020.01.24.20018697
    Journal:
    E-pub date: 1 Aug 2020
    Authors: N Holland, S Jones, G Savulich, J Wiggins, Y Hong, T Fryer, R Manavaki, SM Sephton, I Boros, M Malpetti, F Hezemans, F Aigbirhio, J Coles, J O’Brien, J Rowe

    Influence of secondary sources in the Brief Negative Symptom Scale.

    DOI: http://doi.org/10.1016/j.schres.2018.10.004
    Journal: SCHIZOPHRENIA RESEARCH
    E-pub date: 1 Aug 2019
    Authors: D Treen, G Savulich, G Mezquida, MP García-Portilla, A Toll, C García-Rizo, L García-Álvarez, D Bergé, J Bobes, M Bernardo, E Fernandez-Egea, A Mané

    Obstetric Phenotypes in the Heterogeneity of Schizophrenia.

    DOI: http://doi.org/10.1097/NMD.0000000000000897
    Journal: J Nerv Ment Dis
    E-pub date: 1 Nov 2018
    Authors: G Mezquida, E Fernandez-Egea, D Treen, A Mané, D Bergé, G Savulich, L Garcia-Alvarez, P García-Portilla, J Bobes, M Bernardo, C Garcia-Rizo

    Personalised treatments for traumatic brain injury: cognitive, emotional and motivational targets.

    DOI: http://doi.org/10.1017/S0033291718000892
    Journal: Psychol Med
    E-pub date: 1 Jul 2018
    Authors: G Savulich, DK Menon, EA Stamatakis, JD Pickard, BJ Sahakian

    A Case Study of Clozapine and Cognition: Friend or Foe?

    DOI: http://doi.org/10.1097/JCP.0000000000000847
    Journal: J Clin Psychopharmacol
    E-pub date: 1 Apr 2018
    Authors: G Savulich, G Mezquida, S Atkinson, M Bernardo, E Fernandez-Egea

    Inverse association between negative symptoms and body mass index in chronic schizophrenia.

    DOI: http://doi.org/10.1016/j.schres.2017.04.002
    Journal: Schizophr Res
    E-pub date: 1 Feb 2018
    Authors: G Mezquida, G Savulich, C Garcia-Rizo, MP Garcia-Portilla, A Toll, L Garcia-Alvarez, J Bobes, A Mané, M Bernardo, E Fernandez-Egea

    Association of the brain-derived neurotrophic factor Val66Met polymorphism with negative symptoms severity, but not cognitive function, in first-episode schizophrenia spectrum disorders.

    DOI: http://doi.org/10.1016/j.eurpsy.2016.04.011
    Journal: Eur Psychiatry
    E-pub date: 1 Oct 2016
    Authors: G Mezquida, R Penadés, B Cabrera, G Savulich, A Lobo, A González-Pinto, MJ Penzol, I Corripio, E Fernandez-Egea, P Gassó, MJ Cuesta, M Bernardo, PEPs group

    Valence-dependent influence of serotonin depletion on model-based choice strategy.

    DOI: http://doi.org/10.1038/mp.2015.46
    Journal: Mol Psychiatry
    E-pub date: 1 May 2016
    Authors: Y Worbe, S Palminteri, G Savulich, ND Daw, E Fernandez-Egea, TW Robbins, V Voon

    The impact of neuroscience on society: cognitive enhancement in neuropsychiatric disorders and in healthy people.

    DOI: http://doi.org/10.1098/rstb.2014.0214
    Journal: Philos Trans R Soc Lond B Biol Sci
    E-pub date: 19 Sep 2015
    Authors: BJ Sahakian, AB Bruhl, J Cook, C Killikelly, G Savulich, T Piercy, S Hafizi, J Perez, E Fernandez-Egea, J Suckling, PB Jones

    Tryptophan Depletion Promotes Habitual over Goal-Directed Control of Appetitive Responding in Humans.

    DOI: http://doi.org/10.1093/ijnp/pyv013
    Journal: Int J Neuropsychopharmacol
    E-pub date: 5 Feb 2015
    Authors: Y Worbe, G Savulich, S de Wit, E Fernandez-Egea, TW Robbins

    Serotonin depletion induces ‘waiting impulsivity’ on the human four-choice serial reaction time task: cross-species translational significance.

    DOI: http://doi.org/10.1038/npp.2013.351
    Journal: Neuropsychopharmacology
    E-pub date: 1 May 2014
    Authors: Y Worbe, G Savulich, V Voon, E Fernandez-Egea, TW Robbins