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    Dr Hisham Ziauddeen MRCPsych PhD

    University Position
    Clinical Research Associate

    Interests

    I am a Senior Clinical Research Associate working with Prof. Paul Fletcher. I work on brain reward systems using pharmacological fMRI and behavioural measures, to study the role of environmental influences and opioid and dopaminergic systems in controlling food reward processing and eating behaviour. In collaboration with GSK, we have recently completed a proof of concept study of a novel mu-opioid antagonist. My current work involves the use of pharmacological fMRI to study the role of the dopaminergic system in food reward processing in healthy controls. This work has a particular focus on the effect of the atypical antipsychotics which cause significant weight gain with serious consequences for health. As a side interest, I have spent some time looking at the matter of food addiction both in the scientific literature and in stand up comedy (sets on YouTube) I am also an honorary consultant psychiatrist working with the Cambridgeshire and Peterborough Foundation Trust (CPFT).

    Key Publications

    Birth weight, family history of diabetes and diabetes onset in schizophrenia.

    DOI: http://doi.org/10.1136/bmjdrc-2019-001036
    Journal: BMJ Open Diabetes Res Care
    E-pub date: 1 Jan 2020
    Authors: E Fernandez-Egea, R Walker, H Ziauddeen, RN Cardinal, ET Bullmore

    Publications

    Characterizing cerebral metabolite profiles in anorexia and bulimia nervosa and their associations with habitual behavior.

    DOI: http://doi.org/10.1038/s41398-022-01872-7
    Journal: Translational Psychiatry
    E-pub date: 15 Mar 2022
    Authors: ML Westwater, AG Murley, KMJ Diederen, TA Carpenter, H Ziauddeen, PC Fletcher

    Characterizing cerebral metabolite profiles in anorexia and bulimia nervosa and their associations with habitual behavior

    DOI: http://doi.org/10.1101/2021.09.12.21263466
    Journal:
    E-pub date: 1 Aug 2021
    Authors: M Westwater, A Murley, KMJ Diederen, A Carpenter, H Ziauddeen, P Fletcher

    The role of oxytocin in the facial mimicry of affiliative vs. non-affiliative emotions.

    DOI: http://doi.org/10.1016/j.psyneuen.2019.104377
    Journal: Psychoneuroendocrinology
    E-pub date: 1 Nov 2019
    Authors: G Pavarini, R Sun, M Mahmoud, I Cross, S Schnall, A Fischer, J Deakin, H Ziauddeen, A Kogan, L Vuillier