EMAIL hz238@cam.ac.uk

Department

School

Clinical Medicine

Click to view ORCID profile

Research Theme Beyond the Neuron Adaptive Brain Computations

Research Focus

Keywords

Antipsychotics

Psychosis

Borderline Personality Disorder

Clinical Conditions

Psychotic disorders

Borderline personality disorder

Eating disorders

Equipment & Techniques

Magnetic resonance imaging (MRI)

Neuropsychological testing

Statistical analysis

Science Culture

Equality, Diversity, Inclusion and Wellbeing

Public Engagement

Science & Social Media

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Dr Hisham Ziauddeen MRCPsych PhD

(he/him/his)

University Position

Visiting Scientist
Honorary Fellow

Interests

I was a Senior Clinical Research Associate working with Prof. Paul Fletcher till September 2022. I am currently an Honorary Visiting Senior Fellow in the department of Psychiatry and remain a member of the Fletcher lab. My current work (led by Charley Peiztmeier and Farah Hina) looks at psychosis in borderline personality disorder and interoception in health-related behaviours. My previous work has examined the role of brain reward systems using pharmacological fMRI and behavioural measures, to study the role of environmental influences and opioid and dopaminergic systems in controlling food reward processing and eating behaviour. I have also been involved in research into the brain and endocrine mechanisms of eating disorders, led by Dr Margaret Westwater. I was an honorary consultant psychiatrist working with the Cambridgeshire and Peterborough Foundation Trust (CPFT) in the CAMEO Early Intervention in Psychosis service from December 2017 till September 2022 and currently work in the South Metropolitan Health Service in WA as a consultant psychiatrist.

Collaborators

Cambridge

Paul Fletcher

Karen Ersche

Key Publications

Brain charts for the human lifespan

DOI: http://doi.org/10.1101/2021.06.08.447489
Journal:
E-pub date: 1 Aug 2021
Authors: RAI Bethlehem, J Seidlitz, SR White, JW Vogel, KM Anderson, C Adamson, S Adler, GS Alexopoulos, E Anagnostou, A Areces-Gonzalez, DE Astle, B Auyeung, M Ayub, G Ball, S Baron-Cohen, R Beare, SA Bedford, V Benegal, F Beyer, J Bin Bae, J Blangero, M Blesa Cábez, JP Boardman, M Borzage, JF Bosch-Bayard, N Bourke, VD Calhoun, MM Chakravarty, C Chen, C Chertavian, G Chetelat, YS Chong, JH Cole, A Corvin, M Costantino, E Courchesne, F Crivello, VL Cropley, J Crosbie, N Crossley, M Delarue, R Delorme, S Desrivieres, G Devenyi, MA Di Biase, R Dolan, KA Donald, G Donohoe, K Dunlop, AD Edwards, JT Elison, CT Ellis, JA Elman, L Eyler, DA Fair, E Feczko, PC Fletcher, P Fonagy, CE Franz, L Galan-Garcia, A Gholipour, J Giedd, JH Gilmore, DC Glahn, I Goodyer, PE Grant, NA Groenewold, FM Gunning, RE Gur, RC Gur, CF Hammill, O Hansson, T Hedden, A Heinz, RN Henson, K Heuer, J Hoare, B Holla, AJ Holmes, R Holt, H Huang, K Im, J Ipser, CR Jack, AP Jackowski, T Jia, KA Johnson, PB Jones, DT Jones, R Kahn, H Karlsson, L Karlsson, R Kawashima, EA Kelley, S Kern, K Kim, MG Kitzbichler, WS Kremen, F Lalonde, B Landeau, S Lee, J Lerch, JD Lewis, J Li, W Liao, C Liston, MV Lombardo, J Lv, C Lynch, TT Mallard, M Marcelis, RD Markello, SR Mathias, B Mazoyer, P McGuire, MJ Meaney, A Mechelli, N Medic, B Misic, SE Morgan, D Mothersill, J Nigg, MQW Ong, C Ortinau, C Ortinau, R Ossenkoppele, M Ouyang, L Palaniyappan, L Paly, PM Pan, C Pantelis, MM Park, T Paus, Z Pausova, D Paz-Linares, A Pichet Binette, K Pierce, X Qian, J Qiu, A Qiu, A Raznahan, T Rittman, A Rodrigue, CK Rollins, R Romero-Garcia, L Ronan, MD Rosenberg, DH Rowitch, GA Salum, TD Satterthwaite, HL Schaare, RJ Schachar, AP Schultz, G Schumann, M Schöll, D Sharp, RT Shinohara, I Skoog, CD Smyser, RA Sperling, DJ Stein, A Stolicyn, J Suckling, G Sullivan, Y Taki, B Thyreau, R Toro, N Traut, KA Tsvetanov, NB Turk-Browne, JJ Tuulari, C Tzourio, É Vachon-Presseau, MJ Valdes-Sosa, PA Valdes-Sosa, SL Valk, T van Amelsvoort, SN Vandekar, L Vasung, LW Victoria, S Villeneuve, A Villringer, A Villringer, PE Vértes, K Wagstyl, YS Wang, SK Warfield, V Warrier, E Westman, ML Westwater, HC Whalley, AV Witte, N Yang, B Yeo, H Yun, A Zalesky, HJ Zar, A Zettergren, JH Zhou, H Ziauddeen, A Zugman, XN Zuo, ET Bullmore, AF Alexander-Bloch, 3R-BRAIN, AIBL, Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Repository Without Borders Investigators, UMN BCP, CALM Team, Cam-CAN, CCNP, COBRE, Developing Human Connectome Project, ENIGMA Developmental Brain Age working group, FinnBrain, Harvard Aging Brain Study, IMAGEN, KNE96, The Mayo Clinic Study of Aging, NSPN, POND, The PREVENT-AD Research Group, VETSA

Scientific consensus on the COVID-19 pandemic: we need to act now.

DOI: http://doi.org/10.1016/S0140-6736(20)32153-X
Journal: Lancet
E-pub date: 31 Oct 2020
Authors: NA Alwan, RA Burgess, S Ashworth, R Beale, N Bhadelia, D Bogaert, J Dowd, I Eckerle, LR Goldman, T Greenhalgh, D Gurdasani, A Hamdy, WP Hanage, EB Hodcroft, Z Hyde, P Kellam, M Kelly-Irving, F Krammer, M Lipsitch, A McNally, M McKee, A Nouri, D Pimenta, V Priesemann, H Rutter, J Silver, D Sridhar, C Swanton, RP Walensky, G Yamey, H Ziauddeen

The Presence of Real Food Usurps Hypothetical Health Value Judgment in Overweight People.

DOI: http://doi.org/10.1523/ENEURO.0025-16.2016
Journal: eNeuro
E-pub date: 1 Aug 2016
Authors: N Medic, H Ziauddeen, SE Forwood, KM Davies, AL Ahern, SA Jebb, TM Marteau, PC Fletcher

Publications

Prefrontal Cortex Activation and Stopping Performance Underlie the Beneficial Effects of Atomoxetine on Response Inhibition in Healthy Volunteers and Those With Cocaine Use Disorder.

DOI: http://doi.org/10.1016/j.bpsc.2021.08.010
Journal: Biol Psychiatry Cogn Neurosci Neuroimaging
E-pub date: 1 Nov 2022
Authors: P Zhukovsky, S Morein-Zamir, H Ziauddeen, E Fernandez-Egea, C Meng, R Regenthal, BJ Sahakian, ET Bullmore, TW Robbins, JW Dalley, KD Ersche

Trends in inpatient care for psychiatric disorders in NHS hospitals across England, 1998/99-2019/20: an observational time series analysis.

DOI: http://doi.org/10.1007/s00127-021-02215-5
Journal: Soc Psychiatry Psychiatr Epidemiol
E-pub date: 1 May 2022
Authors: M Degli Esposti, H Ziauddeen, L Bowes, A Reeves, AM Chekroud, DK Humphreys, T Ford

Brain charts for the human lifespan

DOI: http://doi.org/10.1038/s41586-022-04554-y
Journal: Nature
E-pub date: 6 Apr 2022
Authors: RAI Bethlehem, J Seidlitz, SR White, JW Vogel, KM Anderson, C Adamson, S Adler, GS Alexopoulos, E Anagnostou, A Areces-Gonzalez, DE Astle, B Auyeung, M Ayub, G Ball, S Baron-Cohen, R Beare, SA Bedford, V Benegal, F Beyer, J Bin Bae, J Blangero, M Blesa Cábez, JP Boardman, M Borzage, JF Bosch-Bayard, N Bourke, VD Calhoun, MM Chakravarty, C Chen, C Chertavian, G Chetelat, YS Chong, JH Cole, A Corvin, E Courchesne, F Crivello, VL Cropley, J Crosbie, N Crossley, M Delarue, S Desrivieres, G Devenyi, MA Di Biase, R Dolan, KA Donald, G Donohoe, K Dunlop, AD Edwards, JT Elison, CT Ellis, JA Elman, L Eyler, DA Fair, PC Fletcher, P Fonagy, CE Franz, L Galan-Garcia, A Gholipour, J Giedd, JH Gilmore, DC Glahn, I Goodyer, PE Grant, NA Groenewold, FM Gunning, RE Gur, RC Gur, CF Hammill, O Hansson, T Hedden, A Heinz, R Henson, K Heuer, J Hoare, B Holla, AJ Holmes, R Holt, H Huang, K Im, J Ipser, CR Jack, AP Jackowski, T Jia, KA Johnson, PB Jones, DT Jones, R Kahn, H Karlsson, L Karlsson, R Kawashima, EA Kelley, S Kern, K Kim, MG Kitzbichler, WS Kremen, F Lalonde, B Landeau, S Lee, J Lerch, JD Lewis, J Li, W Liao, DP Linares, C Liston, MV Lombardo, J Lv, C Lynch, TT Mallard, M Marcelis, RD Markello, B Mazoyer, P McGuire, MJ Meaney, A Mechelli, N Medic, B Misic, SE Morgan, D Mothersill, J Nigg, MQW Ong, C Ortinau, R Ossenkoppele, M Ouyang, L Palaniyappan, L Paly, PM Pan, C Pantelis, MM Park, T Paus, Z Pausova, A Pichet Binette, K Pierce, X Qian, J Qiu, A Qiu, A Raznahan, T Rittman, CK Rollins, R Romero-Garcia, L Ronan, MD Rosenberg, DH Rowitch, GA Salum, TD Satterthwaite, HL Schaare, RJ Schachar, AP Schultz, G Schumann, M Schöll, D Sharp, RT Shinohara, I Skoog, CD Smyser, RA Sperling, DJ Stein, A Stolicyn, J Suckling, G Sullivan, Y Taki, B Thyreau, R Toro, KA Tsvetanov, NB Turk-Browne, JJ Tuulari, C Tzourio, É Vachon-Presseau, MJ Valdes-Sosa, PA Valdes-Sosa, SL Valk, T van Amelsvoort, SN Vandekar, L Vasung, LW Victoria, S Villeneuve, A Villringer, PE Vértes, K Wagstyl, YS Wang, SK Warfield, V Warrier, E Westman, ML Westwater, HC Whalley, AV Witte, N Yang, BTT Yeo, HJ Yun, A Zalesky, HJ Zar, A Zettergren, JH Zhou, H Ziauddeen, A Zugman, XN Zuo, AF Alexander-Bloch, AIBL, Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Repository Without Borders Investigators, ASRB, CALM Team, Cam-CAN, CCNP, 3R-BRAIN, COBRE, ENIGMA Developmental Brain Age working group, FinnBrain, Harvard Aging Brain Study, IMAGEN, KNE96, NSPN, OASIS-3, OpenPain Project, POND, The PREVENT-AD Research Group, VETSA, Bullmore, E.T

Characterizing cerebral metabolite profiles in anorexia and bulimia nervosa and their associations with habitual behavior.

DOI: http://doi.org/10.1038/s41398-022-01872-7
Journal: Translational Psychiatry
E-pub date: 15 Mar 2022
Authors: ML Westwater, AG Murley, KMJ Diederen, TA Carpenter, H Ziauddeen, PC Fletcher

Covid-19: An urgent call for global “vaccines-plus” action.

DOI: http://doi.org/10.1136/bmj.o1
Journal: BMJ
E-pub date: 2 Jan 2022
Authors: An open letter by a group of public health experts, clinicians, scientists

Long COVID in children.

DOI: http://doi.org/10.1016/S2352-4642(21)00342-4
Journal: Lancet Child Adolesc Health
E-pub date: 1 Jan 2022
Authors: D Gurdasani, A Akrami, VC Bradley, A Costello, T Greenhalgh, S Flaxman, M McKee, S Michie, C Pagel, S Rasmussen, G Scally, C Yates, H Ziauddeen

Dissociable hormonal profiles for psychopathology and stress in anorexia and bulimia nervosa.

DOI: http://doi.org/10.1017/S0033291720001440
Journal: Psychol Med
E-pub date: 1 Dec 2021
Authors: ML Westwater, F Mancini, J Shapleske, J Serfontein, M Ernst, H Ziauddeen, PC Fletcher

Vaccinating adolescents against SARS-CoV-2 in England: a risk-benefit analysis.

DOI: http://doi.org/10.1177/01410768211052589
Journal: J R Soc Med
E-pub date: 1 Nov 2021
Authors: D Gurdasani, S Bhatt, A Costello, S Denaxas, S Flaxman, T Greenhalgh, S Griffin, Z Hyde, A Katzourakis, M McKee, S Michie, O Ratmann, S Reicher, G Scally, C Tomlinson, C Yates, H Ziauddeen, C Pagel

Modelling the impact of lockdown-easing measures on cumulative COVID-19 cases and deaths in England.

DOI: http://doi.org/10.1136/bmjopen-2020-042483
Journal: BMJ Open
E-pub date: 8 Sep 2021
Authors: H Ziauddeen, N Subramaniam, D Gurdasani

Precision weighting of cortical unsigned prediction error signals benefits learning, is mediated by dopamine, and is impaired in psychosis.

DOI: http://doi.org/10.1038/s41380-020-0803-8
Journal: Mol Psychiatry
E-pub date: 1 Sep 2021
Authors: J Haarsma, PC Fletcher, JD Griffin, HJ Taverne, H Ziauddeen, TJ Spencer, C Miller, T Katthagen, I Goodyer, KMJ Diederen, GK Murray

Characterizing cerebral metabolite profiles in anorexia and bulimia nervosa and their associations with habitual behavior

DOI: http://doi.org/10.1101/2021.09.12.21263466
Journal:
E-pub date: 1 Aug 2021
Authors: M Westwater, A Murley, KMJ Diederen, A Carpenter, H Ziauddeen, P Fletcher

Atomoxetine partially restores loss sensitivity in cocaine use disorder

DOI: http://doi.org/10.1016/j.euroneuro.2021.10.016
Journal:
E-pub date: 1 Aug 2021
Authors: L Cincikas, RN Cardinal, H Ziauddeen, E Fernandez-Egea, R Regenthal, BJ Sahakian, TW Robbins, KD Ersche

Mass infection is not an option: we must do more to protect our young.

DOI: http://doi.org/10.1016/S0140-6736(21)01589-0
Journal: Lancet
E-pub date: 24 Jul 2021
Authors: D Gurdasani, J Drury, T Greenhalgh, S Griffin, Z Haque, Z Hyde, A Katzourakis, M McKee, S Michie, C Pagel, S Reicher, A Roberts, R West, C Yates, H Ziauddeen

Prefrontal Responses during Proactive and Reactive Inhibition Are Differentially Impacted by Stress in Anorexia and Bulimia Nervosa.

DOI: http://doi.org/10.1523/JNEUROSCI.2853-20.2021
Journal: J Neurosci
E-pub date: 19 May 2021
Authors: ML Westwater, F Mancini, AX Gorka, J Shapleske, J Serfontein, C Grillon, M Ernst, H Ziauddeen, PC Fletcher

School reopening without robust COVID-19 mitigation risks accelerating the pandemic.

DOI: http://doi.org/10.1016/S0140-6736(21)00622-X
Journal: Lancet
E-pub date: 27 Mar 2021
Authors: D Gurdasani, NA Alwan, T Greenhalgh, Z Hyde, L Johnson, M McKee, S Michie, KA Prather, SD Rasmussen, S Reicher, P Roderick, H Ziauddeen

Feeding the addiction: Narrowing of goals to habits.

DOI: http://doi.org/10.1016/j.euroneuro.2020.11.002
Journal: Eur Neuropsychopharmacol
E-pub date: 1 Jan 2021
Authors: JR Breedon, H Ziauddeen, J Stochl, KD Ersche

The UK needs a sustainable strategy for COVID-19.

DOI: http://doi.org/10.1016/S0140-6736(20)32350-3
Journal: Lancet
E-pub date: 5 Dec 2020
Authors: D Gurdasani, L Bear, D Bogaert, RA Burgess, R Busse, R Cacciola, Y Charpak, T Colbourn, J Drury, K Friston, V Gallo, LR Goldman, T Greenhalgh, Z Hyde, K Kuppalli, MS Majumder, JM Martin-Moreno, M McKee, S Michie, E Mossialos, A Nouri, C Pagel, D Pimenta, S Popescu, V Priesemann, AL Rasmussen, S Reicher, W Ricciardi, K Rice, J Silver, TC Smith, C Wenham, R West, G Yamey, C Yates, H Ziauddeen

Prefrontal responses during proactive and reactive inhibition are differentially impacted by stress in anorexia and bulimia nervosa

DOI: http://doi.org/10.1101/2020.02.27.968719
Journal:
E-pub date: 1 Aug 2020
Authors: ML Westwater, F Mancini, AX Gorka, J Shapleske, J Serfontein, C Grillon, M Ernst, H Ziauddeen, PC Fletcher

Brain networks underlying vulnerability and resilience to drug addiction.

DOI: http://doi.org/10.1073/pnas.2002509117
Journal: Proc Natl Acad Sci U S A
E-pub date: 30 Jun 2020
Authors: KD Ersche, C Meng, H Ziauddeen, J Stochl, GB Williams, ET Bullmore, TW Robbins

On the fallibility of simulation models in informing pandemic responses.

DOI: http://doi.org/10.1016/S2214-109X(20)30219-9
Journal: Lancet Glob Health
E-pub date: 1 Jun 2020
Authors: D Gurdasani, H Ziauddeen

Birth weight, family history of diabetes and diabetes onset in schizophrenia.

DOI: http://doi.org/10.1136/bmjdrc-2019-001036
Journal: BMJ Open Diabetes Res Care
E-pub date: 1 Jan 2020
Authors: E Fernandez-Egea, R Walker, H Ziauddeen, RN Cardinal, ET Bullmore

Combined effects of age and BMI are related to altered cortical thickness in adolescence and adulthood.

DOI: http://doi.org/10.1016/j.dcn.2019.100728
Journal: Dev Cogn Neurosci
E-pub date: 1 Dec 2019
Authors: ML Westwater, R Vilar-López, H Ziauddeen, A Verdejo-García, PC Fletcher

The role of oxytocin in the facial mimicry of affiliative vs. non-affiliative emotions.

DOI: http://doi.org/10.1016/j.psyneuen.2019.104377
Journal: Psychoneuroendocrinology
E-pub date: 1 Nov 2019
Authors: G Pavarini, R Sun, M Mahmoud, I Cross, S Schnall, A Fischer, J Deakin, H Ziauddeen, A Kogan, L Vuillier

Noradrenergic modulation of stopping impulsivity in cocaine use disorder

DOI: http://doi.org/10.1016/j.euroneuro.2018.11.317
Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
E-pub date: 1 Aug 2019
Authors: R Rodrigues, S Morein-Zamir, C Meng, H Ziauddeen, E Fernandez-Egea, R Regenthal, BJ Sahakian, ET Bullmore, TW Robbins, KD Ersche

Wanting food in cocaine addiction: A more complex relationship

DOI: http://doi.org/10.1016/j.euroneuro.2018.11.732
Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
E-pub date: 1 Aug 2019
Authors: J Breedon, H Ziauddeen, KD Ersche

Combined effects of age and BMI are related to altered cortical thickness in adolescence and adulthood

DOI: http://doi.org/10.1101/596064
Journal:
E-pub date: 1 Aug 2019
Authors: M Westwater, R Vilar-López, H Ziauddeen, A Verdejo-García, P Fletcher

BMI-related cortical morphometry changes are associated with altered white matter structure.

DOI: http://doi.org/10.1038/s41366-018-0269-9
Journal: Int J Obes (Lond)
E-pub date: 1 Mar 2019
Authors: N Medic, P Kochunov, H Ziauddeen, KD Ersche, PJ Nathan, L Ronan, PC Fletcher

Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype.

DOI: http://doi.org/10.1038/npp.2017.287
Journal: Neuropsychopharmacology
E-pub date: 1 Mar 2018
Authors: H Ziauddeen, LJ Nestor, N Subramaniam, C Dodds, PJ Nathan, SR Miller, BK Sarai, K Maltby, D Fernando, L Warren, LK Hosking, D Waterworth, A Korzeniowska, B Win, DB Richards, LV Johnson, PC Fletcher, ET Bullmore

Comparative study of endoscopic surveillance in hereditary diffuse gastric cancer according to CDH1 mutation status.

DOI: http://doi.org/10.1016/j.gie.2017.06.028
Journal: Gastrointest Endosc
E-pub date: 1 Feb 2018
Authors: EZ Mi, EZ Mi, M di Pietro, M O'Donovan, RH Hardwick, S Richardson, H Ziauddeen, PC Fletcher, C Caldas, M Tischkowitz, K Ragunath, RC Fitzgerald

Oxytocin administration suppresses hypothalamic activation in response to visual food cues

DOI: http://doi.org/10.1038/s41598-017-04600-01
Journal: Scientific Reports
E-pub date: 1 Dec 2017
Authors: AA Van Der Klaauw, H Ziauddeen, JM Keogh, E Henning, S Dachi, PC Fletcher, I Sadaf Farooqi

Atomoxetine effects on attentional bias to drug-related cues in cocaine dependent individuals.

DOI: http://doi.org/10.1007/s00213-017-4643-4
Journal: Psychopharmacology (Berl)
E-pub date: 31 Aug 2017
Authors: L Passamonti, M Luijten, H Ziauddeen, ITS Coyle-Gilchrist, T Rittman, SAE Brain, R Regenthal, IHA Franken, BJ Sahakian, ET Bullmore, TW Robbins, KD Ersche

SLC6A2 genotype variation and the modulatory effects of atomoxetine on inhibitory control in individuals with and without cocaine use disorder

DOI: http://doi.org/10.1016/S0924-977X(17)31865-5
Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
E-pub date: 1 Aug 2017
Authors: AN Le, H Ziauddeen, E Fernandez-Egea, R Regenthal, BJ Sahakian, ET Bullmore, TW Robbins, KD Ersche

Disrupted iron regulation in the brain and periphery in cocaine addiction.

DOI: http://doi.org/10.1038/tp.2016.271
Journal: Transl Psychiatry
E-pub date: 21 Feb 2017
Authors: KD Ersche, J Acosta-Cabronero, PS Jones, H Ziauddeen, RPL van Swelm, CMM Laarakkers, R Raha-Chowdhury, GB Williams

Sugar addiction: the state of the science.

DOI: http://doi.org/10.1007/s00394-016-1229-6
Journal: Eur J Nutr
E-pub date: 1 Nov 2016
Authors: ML Westwater, PC Fletcher, H Ziauddeen

Opioid Antagonists and the A118G Polymorphism in the μ-Opioid Receptor Gene: Effects of GSK1521498 and Naltrexone in Healthy Drinkers Stratified by OPRM1 Genotype.

DOI: http://doi.org/10.1038/npp.2016.60
Journal: Neuropsychopharmacology
E-pub date: 1 Oct 2016
Authors: H Ziauddeen, LJ Nestor, N Subramaniam, C Dodds, PJ Nathan, SR Miller, BK Sarai, K Maltby, D Fernando, L Warren, LK Hosking, D Waterworth, A Korzeniowska, B Win, DB Richards, L Vasist Johnson, PC Fletcher, ET Bullmore

Increased body mass index is associated with specific regional alterations in brain structure.

DOI: http://doi.org/10.1038/ijo.2016.42
Journal: Int J Obes (Lond)
E-pub date: 1 Jul 2016
Authors: N Medic, H Ziauddeen, KD Ersche, IS Farooqi, ET Bullmore, PJ Nathan, L Ronan, PC Fletcher

Abnormal Frontostriatal Activity During Unexpected Reward Receipt in Depression and Schizophrenia: Relationship to Anhedonia.

DOI: http://doi.org/10.1038/npp.2015.370
Journal: Neuropsychopharmacology
E-pub date: 1 Jul 2016
Authors: N Segarra, A Metastasio, H Ziauddeen, J Spencer, NR Reinders, RB Dudas, G Arrondo, TW Robbins, L Clark, PC Fletcher, GK Murray

Association of birth weight and the development of antipsychotic induced adiposity in individuals with treatment resistant schizophrenia.

DOI: http://doi.org/10.1016/j.euroneuro.2016.03.008
Journal: Eur Neuropsychopharmacol
E-pub date: 1 Jun 2016
Authors: H Ziauddeen, C Garcia-Rizo, M Bernardo, B Kirkpatrick, SE Ozanne, PB Jones, E Fernandez-Egea

Investigating ‘waiting impulsivity’ in cocaine addiction: are the effects of atomoxetine mediated by genotype?

DOI: http://doi.org/10.1016/S0924-977X(15)30875-0
Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
E-pub date: 1 Aug 2015
Authors: MI Pollard, H Ziauddeen, IT Coyle-Gilchrist, T Rittman, R Regenthal, S Abbott, BJ Sahakian, ET Bullmore, TW Robbins, KD Ersche

Atomoxetine reduces attentional bias to cocaine-related cues irrespective of norepinephrine transporter gene polymorphism

DOI: http://doi.org/10.1016/S0924-977X(15)30881-6
Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
E-pub date: 1 Aug 2015
Authors: CH Popham, M Luijten, H Ziauddeen, SAE Brain, R Regenthal, IH Franken, BJ Sahakian, ET Bullmore, TW Robbins, KE Ersche

Reduction in ventral striatal activity when anticipating a reward in depression and schizophrenia: a replicated cross-diagnostic finding.

DOI: http://doi.org/10.3389/fpsyg.2015.01280
Journal: Front Psychol
E-pub date: 1 Aug 2015
Authors: G Arrondo, N Segarra, A Metastasio, H Ziauddeen, J Spencer, NR Reinders, RB Dudas, TW Robbins, PC Fletcher, GK Murray

Obesity and the neurocognitive basis of food reward and the control of intake.

DOI: http://doi.org/10.3945/an.115.008268
Journal: Adv Nutr
E-pub date: 1 Jul 2015
Authors: H Ziauddeen, M Alonso-Alonso, JO Hill, M Kelley, NA Khan

Effects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects

DOI: http://doi.org/10.1038/mp.2014.126
Journal: Molecular Psychiatry
E-pub date: 30 Sep 2014
Authors: H Ziauddeen, SR Chamberlain, PJ Nathan, A Koch, K Maltby, M Bush, WX Tao, A Napolitano, AL Skeggs, AC Brooke, L Cheke, NS Clayton, I Sadaf Farooqi, S O'Rahilly, D Waterworth, K Song, L Hosking, DB Richards, PC Fletcher, ET Bullmore

Neurocognition: the food–brain connection.

DOI: http://doi.org/10.3945/an.114.006437
Journal: Adv Nutr
E-pub date: 1 Sep 2014
Authors: JO Hill, K Berridge, NM Avena, H Ziauddeen, M Alonso-Alonso, DB Allison, NA Khan, M Kelley

Brain structural signatures of negative symptoms in depression and schizophrenia.

DOI: http://doi.org/10.3389/fpsyt.2014.00116
Journal: Front Psychiatry
E-pub date: 1 Aug 2014
Authors: J-Y Chuang, GK Murray, A Metastasio, N Segarra, R Tait, J Spencer, H Ziauddeen, RB Dudas, PC Fletcher, J Suckling

A study of psychotic symptoms in borderline personality disorder.

DOI: http://doi.org/10.1097/NMD.0000000000000132
Journal: J Nerv Ment Dis
E-pub date: 1 May 2014
Authors: LJ Pearse, C Dibben, H Ziauddeen, C Denman, PJ McKenna

Studying food reward and motivation in humans.

DOI: http://doi.org/10.3791/51281
Journal: Journal of Visualized Experiments
E-pub date: 19 Mar 2014
Authors: H Ziauddeen, N Subramaniam, VC Cambridge, N Medic, IS Farooqi, PC Fletcher

Effects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects.

DOI: http://doi.org/10.1038/mp.2012.154
Journal: Mol Psychiatry
E-pub date: 1 Dec 2013
Authors: H Ziauddeen, SR Chamberlain, PJ Nathan, A Koch, K Maltby, M Bush, WX Tao, A Napolitano, AL Skeggs, AC Brooke, L Cheke, NS Clayton, I Sadaf Farooqi, S O'Rahilly, D Waterworth, K Song, L Hosking, DB Richards, PC Fletcher, ET Bullmore

Central nervous system biomarkers for antiobesity drug development.

DOI: http://doi.org/10.1016/j.drudis.2013.08.015
Journal: Drug Discovery Today
E-pub date: 1 Dec 2013
Authors: H Ziauddeen, PC Fletcher

The effects of alcohol on the pharmacokinetics and pharmacodynamics of the selective mu-opioid receptor antagonist GSK1521498 in healthy subjects.

DOI: http://doi.org/10.1002/jcph.110
Journal: J Clin Pharmacol
E-pub date: 1 Oct 2013
Authors: H Ziauddeen, PJ Nathan, C Dodds, K Maltby, SR Miller, D Waterworth, K Song, L Warren, L Hosking, M Zucchetto, M Bush, LV Johnson, B Sarai, K Mogg, BP Bradley, DB Richards, PC Fletcher, ET Bullmore

Neural and behavioral effects of a novel mu opioid receptor antagonist in binge-eating obese people.

DOI: http://doi.org/10.1016/j.biopsych.2012.10.022
Journal: Biological Psychiatry
E-pub date: 1 May 2013
Authors: VC Cambridge, H Ziauddeen, PJ Nathan, N Subramaniam, C Dodds, SR Chamberlain, A Koch, K Maltby, AL Skeggs, A Napolitano, IS Farooqi, ET Bullmore, PC Fletcher