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Dr Julia Greenland

University Position
PhD student

Interests

I am interested in the role of the immune system in the progression of Parkinson's disease. Together with Dr Williams-Gray, I am running a clinical trial of azathioprine, an immunosuppressant medication, to try to slow down the progression of PD.

Key Publications

Constipation is linked to neuroinflammation in early Parkinson’s disease

DOI: http://doi.org/10.1002/mds.70102
Journal: Mov Disord
E-pub date: 1 Feb 2026
Authors: M Camacho Goncalves, C Williams-Gray

Azathioprine for the treatment of early Parkinson’s disease (AZA-PD): a randomised, double-blind, placebo-controlled, proof-of-concept, phase 2 trial

DOI: http://doi.org/10.1016/S1474-4422(25)00386-2
Journal: Lancet Neurol
E-pub date: 1 Jan 2026
Authors: JC Greenland, K Dresser, E Cutting, R Donegan, S Bond, SJ Crisp, KM Scott, ZJ Voysey, J Holbrook, L Kahanawita, R Pal, M Camacho, ARD Peattie, LRB Spindler, YT Hong, TD Fryer, CH Williams-Gray

“Recommendations for clinical study protocols for immune and inflammatory profiling in Parkinson’s disease”.

DOI: http://doi.org/10.1038/s41531-025-01146-1
Journal: NPJ Parkinsons Dis
E-pub date: 20 Oct 2025
Authors: L Muñoz-Delgado, CH Williams-Gray, G Garraux, D Clemente, ÖÖ Çakmak, JC Greenland, I Figueira, I Machín-Díaz, E Pirovano, A di Flora, C Tournerie, S Papoutsopoulou, S Ertan, P Mir, C Comi

Peripheral-central immune crosstalk in Parkinson’s disease and its association with clinical severity

DOI: http://doi.org/10.1016/j.bbi.2025.04.028
Journal: Brain Behav Immun
E-pub date: 31 Aug 2025
Authors: JC Greenland, J Holbrook, L Kahanawita, M Camacho, TD Fryer, YT Hong, CH Williams-Gray

The profile of gastrointestinal dysfunction in prodromal to late-stage Parkinson’s disease

DOI: http://doi.org/10.1038/s41531-025-00900-9
Journal: NPJ Parkinsons Dis
E-pub date: 11 May 2025
Authors: M Camacho Goncalves, JC Greenland, C Daruwalla, KM Scott, B Patel, D Apostolopoulos, J Ribeiro, M O'Reilly, MT Hu, CH Williams-Gray

Clinical Trial Highlights: Anti-Inflammatory and Immunomodulatory Agents.

DOI: http://doi.org/10.3233/JPD-240353
Journal: J Parkinsons Dis
E-pub date: 1 Aug 2024
Authors: B Patel, JC Greenland, CH Williams-Gray

The Gastrointestinal Dysfunction Scale for Parkinson’s Disease.

DOI: http://doi.org/10.1002/mds.28675
Journal: Mov Disord
E-pub date: 1 Oct 2021
Authors: M Camacho, JC Greenland, CH Williams-Gray

Publications

Validation of a 5-Year Prognostic Model for Parkinson’s Disease.

DOI: http://doi.org/10.1002/mdc3.14215
Journal: Mov Disord Clin Pract
E-pub date: 1 Nov 2024
Authors: J Ribeiro, M Camacho, KM Scott, JC Greenland, JR Evans, DP Breen, RS Wijeyekoon, RA Barker, CH Williams-Gray

Natural killer cells have an activated profile in early Parkinson’s disease.

DOI: http://doi.org/10.1016/j.jneuroim.2023.578154
Journal: J Neuroimmunol
E-pub date: 15 Sep 2023
Authors: J Holbrook, B Patel, M Camacho, L Kahanawita, J Greenland, CH Williams-Gray

The dilemma between milestones of progression versus clinical scales in Parkinson’s disease.

DOI: http://doi.org/10.1016/B978-0-323-85538-9.00010-9
Journal: Handb Clin Neurol
E-pub date: 1 Aug 2023
Authors: JC Greenland, M Camacho, CH Williams-Gray

Early constipation predicts faster dementia onset in Parkinson’s disease.

DOI: http://doi.org/10.1038/s41531-021-00191-w
Journal: NPJ Parkinsons Dis
E-pub date: 26 May 2021
Authors: M Camacho, AD Macleod, J Maple-Grødem, JR Evans, DP Breen, G Cummins, RS Wijeyekoon, JC Greenland, G Alves, OB Tysnes, RA Lawson, RA Barker, CH Williams-Gray

The clinical heterogeneity of Parkinson’s disease and its therapeutic implications.

DOI: http://doi.org/10.1111/ejn.14094
Journal: Eur J Neurosci
E-pub date: 1 Feb 2019
Authors: JC Greenland, CH Williams-Gray, RA Barker