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Keywords

  • Dementia
  • Clinical Conditions

  • Dementia
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    Joanne Outtrim

    University Position
    Other

    Key Publications

    Metabolic derangements are associated with impaired glucose delivery following traumatic brain injury.

    DOI: http://doi.org/10.1093/brain/awab255
    Journal: Brain
    E-pub date: 16 Dec 2021
    Authors: J Hermanides, YT Hong, M Trivedi, J Outtrim, F Aigbirhio, PJ Nestor, M Guilfoyle, S Winzeck, VFJ Newcombe, T Das, MM Correia, KLH Carpenter, PJA Hutchinson, AK Gupta, TD Fryer, JD Pickard, DK Menon, JP Coles

    Pathophysiologic Mechanisms of Cerebral Ischemia and Diffusion Hypoxia in Traumatic Brain Injury.

    DOI: http://doi.org/10.1001/jamaneurol.2016.0091
    Journal: JAMA Neurol
    E-pub date: 1 May 2016
    Authors: TV Veenith, EL Carter, T Geeraerts, J Grossac, VFJ Newcombe, J Outtrim, GS Gee, V Lupson, R Smith, FI Aigbirhio, TD Fryer, YT Hong, DK Menon, JP Coles

    Publications

    Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses.

    DOI: http://doi.org/10.1093/brain/awac321
    Journal: Brain
    E-pub date: 6 Sep 2022
    Authors: EJ Needham, AL Ren, RJ Digby, EJ Norton, S Ebrahimi, JG Outtrim, DA Chatfield, AE Manktelow, MM Leibowitz, VFJ Newcombe, R Doffinger, G Barcenas-Morales, C Fonseca, MJ Taussig, RM Burnstein, RJ Samanta, C Dunai, N Sithole, NJ Ashton, H Zetterberg, M Gisslén, A Edén, E Marklund, PJM Openshaw, J Dunning, MJ Griffiths, J Cavanagh, G Breen, SR Irani, A Elmer, N Kingston, C Summers, JR Bradley, LS Taams, BD Michael, ET Bullmore, KGC Smith, PA Lyons, AJ Coles, DK Menon, Cambridge NeuroCOVID Group, CITIID-NIHR COVID-19 BioResource Collaboration, Cambridge NIHR Clinical Research Facility

    Hospitalisation for COVID-19 predicts long lasting cerebrovascular impairment: A prospective observational cohort study

    DOI: http://doi.org/10.1101/2022.02.01.22270235
    Journal:
    E-pub date: 1 Aug 2022
    Authors: K Tsvetanov, L Spindler, E Stamatakis, VFJ Newcombe, V Lupson, D Chatfield, A Manktelow, J Outtrim, A Elmer, N Kingston, J Bradley, E Bullmore, J Rowe, D Menon, The Cambridge NeuroCOVID Group, The NIHR COVID-19 BioResource, The Cambridge NIHR Clinical Research Facility, The CITIID-NIHR BioResource COVID-19 Collaboration

    Brain Injury in COVID-19 is Associated with Autoinflammation and Autoimmunity

    DOI: http://doi.org/10.1101/2021.12.03.21266112
    Journal:
    E-pub date: 1 Aug 2021
    Authors: EJ Needham, AL Ren, RJ Digby, JG Outtrim, DA Chatfield, AE Manktelow, VFJ Newcombe, R Doffinger, G Barcenas-Morales, C Fonseca, MJ Taussig, RM Burnstein, C Dunai, N Sithole, NJ Ashton, H Zetterberg, M Gisslen, A Edén, E Marklund, MJ Griffiths, J Cavanagh, G Breen, SR Irani, A Elmer, N Kingston, JR Bradley, LS Taams, BD Michael, ET Bullmore, KGC Smith, PA Lyons, AJC Coles, DK Menon, the Cambridge NeuroCOVID Group, the NIHR COVID-19 BioResource, Cambridge NIHR Clinical Research Facility

    Depression following traumatic brain injury is characterised by dominant and recurring brain loops in self-referential areas

    DOI: http://doi.org/10.1101/2020.08.14.20175000
    Journal:
    E-pub date: 15 Aug 2020
    Authors: I Pappas, L Moreno-López, E Carroll, A Manktelow, J Outtrim, J Coles, V Newcombe, B Sahakian, D Menon, E Stamatakis

    Neural correlates of visual memory in patients with diffuse axonal injury.

    DOI: http://doi.org/10.1080/02699052.2017.1341998
    Journal: Brain Inj
    E-pub date: 1 Aug 2017
    Authors: J Lauer, L Moreno-López, A Manktelow, EL Carroll, JG Outtrim, JP Coles, VF Newcombe, BJ Sahakian, DK Menon, EA Stamatakis

    Dynamic Changes in White Matter Abnormalities Correlate With Late Improvement and Deterioration Following TBI: A Diffusion Tensor Imaging Study.

    DOI: http://doi.org/10.1177/1545968315584004
    Journal: Neurorehabil Neural Repair
    E-pub date: 1 Jan 2016
    Authors: VFJ Newcombe, MM Correia, C Ledig, MG Abate, JG Outtrim, D Chatfield, T Geeraerts, AE Manktelow, E Garyfallidis, JD Pickard, BJ Sahakian, PJA Hutchinson, D Rueckert, JP Coles, GB Williams, DK Menon

    Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI): a prospective longitudinal observational study.

    DOI: http://doi.org/10.1227/NEU.0000000000000575
    Journal: Neurosurgery
    E-pub date: 1 Jan 2015
    Authors: AIR Maas, DK Menon, EW Steyerberg, G Citerio, F Lecky, GT Manley, S Hill, V Legrand, A Sorgner, CENTER-TBI Participants and Investigators

    Amyloid imaging with carbon 11-labeled Pittsburgh compound B for traumatic brain injury.

    DOI: http://doi.org/10.1001/jamaneurol.2013.4847
    Journal: JAMA Neurol
    E-pub date: 1 Jan 2014
    Authors: YT Hong, T Veenith, D Dewar, JG Outtrim, V Mani, C Williams, S Pimlott, PJA Hutchinson, A Tavares, R Canales, CA Mathis, WE Klunk, FI Aigbirhio, JP Coles, J-C Baron, JD Pickard, TD Fryer, W Stewart, DK Menon

    Microstructural basis of contusion expansion in traumatic brain injury: insights from diffusion tensor imaging.

    DOI: http://doi.org/10.1038/jcbfm.2013.11
    Journal: Journal of Cerebral Blood Flow and Metabolism
    E-pub date: 1 Jun 2013
    Authors: VFJ Newcombe, GB Williams, JG Outtrim, D Chatfield, M Gulia Abate, T Geeraerts, A Manktelow, H Room, L Mariappen, PJ Hutchinson, JP Coles, DK Menon

    Critical thresholds for cerebrovascular reactivity after traumatic brain injury.

    DOI: http://doi.org/10.1007/s12028-011-9630-8
    Journal: Neurocrit Care
    E-pub date: 1 Apr 2012
    Authors: E Sorrentino, J Diedler, M Kasprowicz, KP Budohoski, C Haubrich, P Smielewski, JG Outtrim, A Manktelow, PJ Hutchinson, JD Pickard, DK Menon, M Czosnyka

    Traumatic brain injury alters the functional brain network mediating working memory.

    DOI: http://doi.org/10.3109/02699052.2011.608210
    Journal: Brain Injury
    E-pub date: 1 Jan 2011
    Authors: M Kasahara, DK Menon, CH Salmond, JG Outtrim, JVT Tavares, TA Carpenter, JD Pickard, BJ Sahakian, EA Stamatakis

    Altered functional connectivity in the motor network after traumatic brain injury.

    DOI: http://doi.org/10.1212/WNL.0b013e3181e7ca58
    Journal: Neurology
    E-pub date: 13 Jul 2010
    Authors: M Kasahara, DK Menon, CH Salmond, JG Outtrim, JV Taylor Tavares, TA Carpenter, JD Pickard, BJ Sahakian, EA Stamatakis

    Effect of hyperoxia on regional oxygenation and metabolism after severe traumatic brain injury: preliminary findings.

    DOI: http://doi.org/10.1097/01.CCM.0000292014.60835.15
    Journal: Crit Care Med
    E-pub date: 1 Jan 2008
    Authors: J Nortje, JP Coles, I Timofeev, TD Fryer, FI Aigbirhio, P Smielewski, JG Outtrim, DA Chatfield, JD Pickard, PJ Hutchinson, AK Gupta, DK Menon