• Oncology
  • Research Theme Beyond the Neuron

    Other Interdiciplinary Incentives

  • Cancer
  • Immunology
  • Neuroscience
  • Research Focus


  • Immune-Brain Interactions
  • Neurimmunology
  • Brain Cancer
  • Clinical Conditions

  • Brain cancer
  • Equipment & Techniques

  • Behavioural analysis
  • Confocal microscopy
  • Cell culture
  • Fluorescence microscopy
  • Immunohistochemistry
  • Protein purification
  • Other
  • Science Culture

  • Women in Neuroscience
  • Reproducibility in Science
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    Dr Lucie Pepino

    University Position
    Research Associate


    Lucie received her MSc and PhD degrees in Neuroscience from the University of Aix-Marseille (France). Her PhD project addressed sex-linked differences in an inflammatory pain model in Dr. Aziz Moqrich's lab (advised by Dr. Ana Reynders). Her project was designed to explore differences in pain perception at various levels of analysis, including global behaviour, hormone contribution, and spinal gene expression, in response to inflammatory-evoked pain. By further exploring one of the top upregulated genes in males, she identified a male-female difference in neutrophil recruitment to the spinal meninges, and more specifically to the pia mater. In the Pathania lab, Lucie will investigate how partner mutations in H3K27M and H3.3G34R gliomas modify interactions between brain tumour cells and their microenvironment (blood vessels, microglia, neurons, astrocytes and infiltrating immune cells). Additionnally, she will also investigate how paediatric gliomas modify meninges immunity (including both the dura and the pia mater).

    Key Publications

    Formalin-evoked pain triggers sex-specific behavior and spinal immune response

    Journal: Scientific Reports
    Year: 2023
    Authors: Lucie Pepino; Pascale Malapert; Andrew J. Saurin; Aziz Moqrich; Ana Reynders


    Sex-related exacerbation of injury-induced mechanical hypersensitivity in GAD67 haplodeficient mice

    Journal: Pain
    Year: 2023
    Authors: Aude Charron; Lucie Pepino; Pascale Malapert; Vincent Debrauwer; Francis Castets; Chiara Salio; Aziz Moqrich