Research Focus


  • Electroretinogram
  • Retinal Neural Circuit
  • Retinal Degeneration
  • Retina
  • Photoreceptor
  • Clinical Conditions

  • Genetic disorders
  • Equipment & Techniques

  • Electrophysiological recording techniques
  • Science Culture

  • Teaching
  • Mentorship
  • Back

    Dr Omar Mahroo MA, MB, BChir, PhD, FRCOphth, FHEA, FRSB, FTPS

    University Position
    Affiliated Member


    I investigate human retinal function in health and disease, using electrophysiology and complementary approaches including retinal imaging, genetic investigation and machine learning. I am Professor of Retinal Neuroscience at University College London. My research is based at multiple sites including UCL, KCL, Moorfields Eye Hospital, St Thomas' Hospital. I supervise Part II research projects based at PDN. Key current areas of investigation: Retinal structure and function in inherited retinal diseases and selected acquired diseases; Portable electroretinography recordings; Effect of common and rare genetics variants on retinal function, including variants associated with myopia; Characterising retinal light and dark adaptation in health and disease. Funding: Wellcome Trust, Fight for Sight, Birdshot Uveitis Society, Thomas Pocklington Trust, Moorfields Eye Charity. My Part II research students in 2020 presented their work nationally and internationally: Remi Rufus-Toye received a Rob Clarke Abstract Award at the Future Physiology meeting of the Physiological Society; Megan Margetts received the Eberhard Dodt Memorial Award at the annual symposium of the International Society for Clinical Electrophysiology of Vision. In 2022, my PhD student, Xiaofan Jiang, received the Eberhard Dodt Memorial Award (International Society for Clinical Electrophysiology of Vision) and the Worshipful Company of Spectacle Makers Master's Medal.

    Recording the ERG

    Key Publications

    Sub-cellular level resolution of common genetic variation in the photoreceptor layer identifies continuum between rare disease and common variation

    Journal: PLoS Genet .
    Year: 2023
    Authors: Currant H, Fitzgerald TW, Patel PJ, Khawaja AP; UK Biobank Eye and Vision Consortium; Webster AR, Mahroo OA, Birney E.

    Axial Length Distributions in Patients With Genetically Confirmed Inherited Retinal Diseases

    Journal: Invest Ophthalmol Vis Sci.
    Year: 2022
    Authors: Williams KM, Georgiou M, Kalitzeos A, Chow I, Hysi PG, Robson AG, Lingham G, Chen FK, Mackey DA, Webster AR, Hammond CJ, Prokhoda P, Carroll J, Michaelides M, Mahroo OA

    Electrical responses from human retinal cone pathways associate with a common genetic polymorphism implicated in myopia

    Journal: Proc Natl Acad Sci U S A.
    Year: 2022
    Authors: Jiang X, Xu Z, Soorma T, Tariq A, Bhatti T, Baneke AJ, Pontikos N, Leo SM, Webster AR, Williams KM, Hammond CJ, Hysi PG, Mahroo OA.