Research Focus


  • Aggregate-Prone Proteins
  • Parkinson's Disease
  • Dementia
  • Immune System
  • Clinical Conditions

  • Parkinson's disease
  • Prion diseases
  • Equipment & Techniques

  • Cell culture
  • Enzyme assays
  • Immunohistochemistry
  • Randomised control trials
  • Back

    Dr Reiss Pal

    University Position
    Research Associate


    My research aims to interrogate the role of the immune system in the neuropathogenesis of Parkinson's disease and the progression of dementia. Studies focus on characterising leukocyte and glia activation in relation to CNS protein aggregation and neuronal loss during disease using functional immune assays. Immunophenotyping approaches are also used to determine whether the clinical heterogeneity in Parkinson's disease patients is influenced by the immune system.

    Key Publications


    The Effects of Immune System Modulation on Prion Disease Susceptibility and Pathogenesis

    Journal: International Journal of Molecular Sciences
    Year: 2020
    Authors: Neil Mabbott, Barry Bradford, Reiss Pal, Rachel Young, David Donaldson

    Innate Immune Tolerance in Microglia Does Not Impact on Central Nervous System Prion Disease

    Journal: Frontiers in Cellular Neuroscience
    Year: 2022
    Authors: Reiss Pal, Barry Bradford, Neil Mabbott