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EMAIL sa569@cam.ac.uk
Department
  • Clinical Neurosciences
    • Institute
  • Cambridge Heart and Lung Institute | Cambridge Cardiovascular
    • Research Theme Brains and Machines
    Research Focus

    Keywords

  • Artificial Intelligence
  • Neuroimaging
  • Stroke
  • Clinical Trials

    • Clinical Conditions

  • Stroke

    • Equipment & Techniques

  • Computerised tomography
  • Computational modelling
  • Other

    • Back

    Smriti Agarwal

    University Position
    Assistant Research Professor
    Dr Smriti Agarwal is pleased to consider applications from prospective PhD students.

    Interests

    My research focuses on harnessing AI techniques to refine measurement of treatment effects and prognostication in stroke. By integrating imaging and multimodal data, my work aims to develop sensitive biomarkers for clinical trials.

    Key Publications

    Publications

    There Are No Limits to the Cost-Effectiveness of Mechanical Thrombectomy-Ubi Clot, Ibi Thrombectomy!

    DOI: http://doi.org/10.1161/STROKEAHA.124.048749
    Journal: Stroke
    E-pub date: 1 Dec 2025
    Authors: S Agarwal, TR Meinel, JT Fifi, TN Nguyen, BCV Campbell

    Left atrial appendage occlusion in patients with atrial fibrillation and intracerebral haemorrhage associated with cerebral amyloid angiopathy: a multicentre observational study and pooled analysis of published studies.

    DOI: http://doi.org/10.1136/jnnp-2024-334718
    Journal: J Neurol Neurosurg Psychiatry
    E-pub date: 14 May 2025
    Authors: K Thiankhaw, J Best, S Srivastava, I Prachee, S Agarwal, S Tan, PA Calvert, A Chughtai, R Ang, OR Segal, DJ Werring

    Frailty reduces penumbral volumes and attenuates treatment response in hyperacute ischemic stroke.

    DOI: http://doi.org/10.1093/ageing/afae266
    Journal: Age Ageing
    E-pub date: 28 Nov 2024
    Authors: E Dohle, B Lewis, S Agarwal, EA Warburton, NR Evans

    Tenecteplase versus alteplase for thrombolysis in patients selected by use of perfusion imaging within 4·5 h of onset of ischaemic stroke (TASTE): a multicentre, randomised, controlled, phase 3 non-inferiority trial.

    DOI: http://doi.org/10.1016/S1474-4422(24)00206-0
    Journal: Lancet Neurol
    E-pub date: 31 Aug 2024
    Authors: MW Parsons, V Yogendrakumar, L Churilov, C Garcia-Esperon, BCV Campbell, ML Russell, G Sharma, C Chen, L Lin, BL Chew, FC Ng, A Deepak, PMC Choi, TJ Kleinig, DJ Cordato, TY Wu, JN Fink, H Ma, TG Phan, HS Markus, CA Molina, C-H Tsai, J-T Lee, J-S Jeng, D Strbian, A Meretoja, JF Arenillas, BH Buck, MJ Devlin, H Brown, KS Butcher, B O'Brien, A Sabet, T Wijeratne, A Bivard, RS Grimley, S Agarwal, SK Munshi, GA Donnan, SM Davis, F Miteff, NJ Spratt, CR Levi, TASTE investigators

    Same-day MRI In TIA clinic: have dedicated MRI slots helped improve access to neuroimaging in line with NICE recommendations?

    DOI: http://doi.org/10.7861/fhj.10-3-s82
    Journal: Future Healthc J
    E-pub date: 1 Nov 2023
    Authors: C Cox, NR Rozi, S Agarwal

    The contribution of competing mechanisms in stroke despite anticoagulation in patients with atrial fibrillation.

    DOI: http://doi.org/10.1177/23969873231168367
    Journal: Eur Stroke J
    E-pub date: 1 Jun 2023
    Authors: R Herlekar, A Sur Roy, S Hajiev, I Induruwa, S Agarwal, NR Evans, K Khadjooi, H Markus, E O'Brien, E Warburton, G Zachariah, JJ McCabe

    Hyperacute stroke thrombolysis via telemedicine: a multicentre study of performance, safety and clinical efficacy.

    DOI: http://doi.org/10.1136/bmjopen-2021-057372
    Journal: BMJ Open
    E-pub date: 17 Jan 2022
    Authors: NR Evans, L Sibson, DJ Day, S Agarwal, R Shekhar, EA Warburton

    Collateral response modulates the time-penumbra relationship in proximal arterial occlusions.

    DOI: http://doi.org/10.1212/WNL.0000000000004858
    Journal: Neurology
    E-pub date: 23 Jan 2018
    Authors: S Agarwal, A Bivard, E Warburton, M Parsons, C Levi

    A systematic checklist approach to immunosuppression risk management: An audit of practice at two clinical neuroimmunology centers.

    DOI: http://doi.org/10.1016/j.jneuroim.2017.08.009
    Journal: J Neuroimmunol
    E-pub date: 15 Nov 2017
    Authors: AM Mori, S Agarwal, MWM Lee, M Rafferty, TA Hardy, A Coles, SW Reddel, DS Riminton

    Dominant hemisphere functional networks compensate for structural connectivity loss to preserve phonological retrieval with aging.

    DOI: http://doi.org/10.1002/brb3.495
    Journal: Brain Behav
    E-pub date: 1 Sep 2016
    Authors: S Agarwal, EA Stamatakis, S Geva, EA Warburton

    Is CT-Based Perfusion and Collateral Imaging Sensitive to Time Since Stroke Onset?

    DOI: http://doi.org/10.3389/fneur.2015.00070
    Journal: Front Neurol
    E-pub date: 1 Aug 2015
    Authors: S Agarwal, T Matys, ST Marrapu, DJ Scoffings, J Mitchell, PS Jones, J-C Baron, EA Warburton

    From Time is brain to Physiology is brain: a case for reflection in acute stroke treatment decisions.

    DOI: http://doi.org/10.1093/brain/awv120
    Journal: Brain
    E-pub date: 1 Jul 2015
    Authors: S Agarwal, EA Warburton, J-C Baron

    Thrombolysis delivery by a regional telestroke network–experience from the U.K. National Health Service.

    DOI: http://doi.org/10.1161/JAHA.113.000408
    Journal: J Am Heart Assoc
    E-pub date: 26 Feb 2014
    Authors: S Agarwal, DJ Day, L Sibson, PJ Barry, D Collas, K Metcalf, PE Cotter, P Guyler, EW O'Brien, A O'Brien, D O'Kane, P Owusu-Agyei, P Phillips, R Shekhar, EA Warburton

    Interaction of age with the ischaemic penumbra, leptomeningeal collateral circulation and haemodynamic variables in acute stroke: a pilot study.

    DOI: http://doi.org/10.1136/jnnp-2012-303258
    Journal: Journal of Neurology Neurosurgery and Psychiatry
    E-pub date: 1 Jan 2013
    Authors: S Agarwal, DJ Scoffings, PS Jones, ST Marrapu, PJ Barry, EW O'Brien, J-C Baron, EA Warburton

    Does perfusion computed tomography facilitate clinical decision making for thrombolysis in unselected acute patients with suspected ischaemic stroke?

    DOI: http://doi.org/10.1159/000329310
    Journal: Cerebrovasc Dis
    E-pub date: 1 Aug 2011
    Authors: S Agarwal, PS Jones, JA Alawneh, NM Antoun, PJ Barry, E Carrera, PE Cotter, EW O'Brien, I Salih, DJ Scoffings, J-C Baron, EA Warburton

    Teleneurology: is it really at a distance?

    DOI: http://doi.org/10.1007/s00415-011-5920-5
    Journal: Journal of Neurology
    E-pub date: 1 Jun 2011
    Authors: S Agarwal, EA Warburton

    Motor cortical excitability predicts cognitive phenotypes in amyotrophic lateral sclerosis.

    DOI: https://www.nature.com/articles/s41598-021-81612-x
    Journal: Scientific Reports
    Year: 2021
    Authors: Agarwal S, Highton-Williamson E, Caga J, Howells J, Dharmadasa T, Matamala JM, Ma Y, Shibuya K, Hodges JR, Ahmed RM, Vucic S, Kiernan MC

    Predictors of survival and progression in behavioural variant frontotemporal dementia

    DOI: https://onlinelibrary.wiley.com/doi/full/10.1111/ene.13887
    Journal: European Journal of Neurology
    Year: 2019
    Authors: Agarwal S, Ahmed R, D’Mello M, Foxe D, Kaizik C, Halliday G, Kiernan M, Piguet O, Hodges J

    Primary lateral sclerosis and the amyotrophic lateral sclerosis-frontotemporal dementia spectrum

    DOI: https://www.nature.com/articles/s41598-021-81612-x
    Journal: Journal of Neurology
    Year: 2018
    Authors: Agarwal S, Highton-Williamson E, Caga J, Matamala JM, Dharmadasa T, Howells J, Zoing M, Shibuya K, Geevasinga N, Vucic S, Hodges J, Ahmed RM, Kiernan MC.

    Interrogating cortical function with transcranial magnetic stimulation: Insights from neurodegenerative disease and stroke

    DOI: https://jnnp.bmj.com/content/90/1/47
    Journal: Journal of Neurology, Neurosurgery and Psychiatry
    Year: 2018
    Authors: Agarwal S, Koch G, Hillis AE, Huynh W, Ward NS, Vucic S, Kiernan MC.