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Research Theme Beyond the Neuron
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Miss Sophie Buller

University Position
PhD student

Interests

Our group studies hypothalamic nutrient sensing and its role in the regulation of energy balance.

Key Publications

MC3R links nutritional state to childhood growth and the timing of puberty.

DOI: http://doi.org/10.1038/s41586-021-04088-9
Journal: Nature
E-pub date: 1 Nov 2021
Authors: BYH Lam, A Williamson, S Finer, FR Day, JA Tadross, A Gonçalves Soares, K Wade, P Sweeney, MN Bedenbaugh, DT Porter, A Melvin, KLJ Ellacott, RN Lippert, S Buller, J Rosmaninho-Salgado, GKC Dowsett, KE Ridley, Z Xu, I Cimino, D Rimmington, K Rainbow, K Duckett, S Holmqvist, A Khan, X Dai, EG Bochukova, Genes & Health Research Team, RC Trembath, HC Martin, AP Coll, DH Rowitch, NJ Wareham, DA van Heel, N Timpson, RB Simerly, KK Ong, RD Cone, C Langenberg, JRB Perry, GS Yeo, S O'Rahilly

Publications

Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence.

DOI: http://doi.org/10.1016/j.celrep.2021.109362
Journal: Cell Rep
E-pub date: 13 Jul 2021
Authors: S Kohnke, S Buller, D Nuzzaci, K Ridley, B Lam, H Pivonkova, MA Bentsen, KM Alonge, C Zhao, J Tadross, S Holmqvist, T Shimizu, H Hathaway, H Li, W Macklin, MW Schwartz, WD Richardson, GSH Yeo, RJM Franklin, RT Karadottir, DH Rowitch, C Blouet

Nutritional signals rapidly activate oligodendrocyte differentiation in the adult hypothalamic median eminence

DOI: http://doi.org/10.1101/751198
Journal:
E-pub date: 1 Aug 2019
Authors: S Kohnke, B Lam, S Buller, C Zhao, D Nuzzaci, J Tadross, S Holmqvist, K Ridley, H Hathaway, W Macklin, GSH Yeo, RJM Franklin, D Rowitch, C Blouet