Sofia Kapsiani

(she/her/hers)

University Position

PhD student

Interests

My research involves combining advanced microscopy and machine learning to study protein aggregation in neurodegenerative diseases.

Key Publications

Discovery of TDP-43 aggregation inhibitors via a hybrid machine learning framework

DOI: http://doi.org/10.64898/2026.02.12.705375
Journal:
E-pub date: 13 Feb 2026
Authors: S Kapsiani, S Vora, A Fernandez-Villegas, CF Kaminski, NF Läubli, GS Kaminski Schierle

Deep Learning for Fluorescence Lifetime Predictions Enables High-Throughput In Vivo Imaging.

DOI: http://doi.org/10.1021/jacs.5c03749
Journal: J Am Chem Soc
E-pub date: 2 Jul 2025
Authors: S Kapsiani, NF Läubli, EN Ward, A Fernandez-Villegas, B Mazumder, CF Kaminski, GS Kaminski Schierle

FLIMPA: A Versatile Software for Fluorescence Lifetime Imaging Microscopy Phasor Analysis.

DOI: http://doi.org/10.1021/acs.analchem.5c00495
Journal: Anal Chem
E-pub date: 10 Jun 2025
Authors: S Kapsiani, NF Läubli, EN Ward, M Shehata, CF Kaminski, GS Kaminski Schierle

Random forest classification for predicting lifespan-extending chemical compounds

DOI: https://doi.org/10.1038/s41598-021-93070-6
Journal: Scientific reports
Year: 2021
Authors: Sofia Kapsiani, Brendan J Howlin

Publications

Multiplex neurodegeneration proteotoxicity platform reveals DNAJB6 promotes non-toxic FUS condensate gelation and inhibits neurotoxicity

DOI: http://doi.org/10.1038/s41467-025-65178-0
Journal: Nat Commun
E-pub date: 21 Nov 2025
Authors: SJ Resnick, S Qamar, P Krishna, V Korobeynikov, H Ausserwoger, A Miller, P Esposito, JA Varela, J Sheng, LH Huang, J Nixon-Abell, S Melore, CW Chung, NF Läubli, S Kapsiani, X Li, J Wang, N Zhang, MM Alam, AS Burguete, TC Swayne, Y Chen, Y-C Liao, NA Shneider, M Vendruscolo, TPJ Knowles, CF Kaminski, FS Ruggeri, GS Kaminski Schierle, P St George-Hyslop, A Chavez