Dr Wei-Li Kuan

University Position

Principal Research Associate

Key Publications

Peripheral innate immune and bacterial signals relate to clinical heterogeneity in Parkinson’s disease.

DOI: http://doi.org/10.1016/j.bbi.2020.01.018
Journal: Brain Behav Immun
E-pub date: 1 Jul 2020
Authors: RS Wijeyekoon, D Kronenberg-Versteeg, KM Scott, S Hayat, W-L Kuan, JR Evans, DP Breen, G Cummins, JL Jones, MR Clatworthy, RA Floto, RA Barker, CH Williams-Gray

Publications

Transcription factor combinations that define human astrocyte identity encode significant variation of maturity and function.

DOI: http://doi.org/10.1002/glia.24372
Journal: Glia
E-pub date: 31 Aug 2023
Authors: K Baranes, N Hastings, S Rahman, N Poulin, JM Tavares, W-L Kuan, N Syed, M Kunz, K Blighe, TG Belgard, MRN Kotter

Selective neurodegeneration generated by intravenous α-synuclein pre-formed fibril administration is not associated with endogenous α-synuclein levels in the rat brain.

DOI: http://doi.org/10.1111/bpa.13128
Journal: Brain Pathol
E-pub date: 1 May 2023
Authors: W-L Kuan, M Alfaidi, CB Horne, B Vallin, S Fox, SV Fazal, CH Williams-Gray, RA Barker

DJ-1 can form β-sheet structured aggregates that co-localize with pathological amyloid deposits.

DOI: http://doi.org/10.1016/j.nbd.2019.104629
Journal: Neurobiol Dis
E-pub date: 1 Feb 2020
Authors: K Solti, W-L Kuan, B Fórizs, G Kustos, J Mihály, Z Varga, B Herberth, É Moravcsik, R Kiss, M Kárpáti, A Mikes, Y Zhao, T Imre, J-C Rochet, F Aigbirhio, CH Williams-Gray, RA Barker, G Tóth

α-Synuclein pre-formed fibrils impair tight junction protein expression without affecting cerebral endothelial cell function.

DOI: http://doi.org/10.1016/j.expneurol.2016.09.003
Journal: Exp Neurol
E-pub date: 1 Nov 2016
Authors: W-L Kuan, N Bennett, X He, JN Skepper, N Martynyuk, R Wijeyekoon, PV Moghe, CH Williams-Gray, RA Barker