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    Professor Zoe Kourtzi

    University Position


    My work aims to understand the role of learning and experience in enabling humans of all ages to translate sensory experience into complex decisions and adaptive behaviours. Adaptive cognitive abilities are critical for survival and social interactions, yet extracting meaning from the complex, and frequently ambiguous, input of the natural world is a computationally demanding task that is far from understood. I address this challenge through an interdisciplinary approach that combines behavioural paradigms with multimodal brain imaging (MRI, EEG, MEG, TMS) and state-of-the-art computational methods. I apply these techniques to study the young and ageing brain and understand learning and cortical plasticity across the lifespan.

    Key Publications


    Predicting incident dementia in cerebral small vessel disease: comparison of machine learning and traditional statistical models.

    Journal: Cereb Circ Cogn Behav
    E-pub date: 1 Aug 2023
    Authors: R Li, EL Harshfield, S Bell, M Burkhart, AM Tuladhar, S Hilal, DJ Tozer, FM Chappell, SDJ Makin, JW Lo, JM Wardlaw, F-E de Leeuw, C Chen, Z Kourtzi, HS Markus

    The Early Detection of Neurodegenerative diseases initiative: an international and multidisciplinary effort for transforming the early detection of dementia‐causing diseases

    Journal: Alzheimer's & Dementia
    E-pub date: 1 Jun 2023
    Authors: F Marinaro, C Morvan, R Au, S Bond, MC Burkhart, N Carlebach, D Chan, D Delbarre, L Farier, A Lacey, H LaMonica, CL Lancaster, LY Lee, DJ Llewellyn, A Mallon, RN Martins, RM Ardle, CJ Mummery, SL Naismith, M Oldham, S Rainey‐Smith, L Santos, S Slight, N Smith, S Thomas, J Venton, C Tolley, K Whitaker, J Wright, S Wilson, K Wing, J Crawford, P Dagum, C Routledge, Z Walker, R Everson, C Hinds, Z Kourtzi

    GABA and glutamate deficits from frontotemporal lobar degeneration are associated with disinhibition.

    Journal: Brain
    E-pub date: 5 Dec 2020
    Authors: AG Murley, MA Rouse, PS Jones, R Ye, FH Hezemans, C O'Callaghan, P Frangou, Z Kourtzi, C Rua, TA Carpenter, CT Rodgers, JB Rowe

    A cross‐cohort cognitive composite for tracking changes in pre‐clinical and prodromal Alzheimer’s disease

    Journal: Alzheimer's & Dementia
    E-pub date: 1 Dec 2020
    Authors: J Giorgio, A Tanna, WJ Jagust, SL Baker, SM Landau, T Tanaka, CP Chen, A Reilhac, M Malpetti, JB Rowe, JT O'Brien, Z Kourtzi

    Recurrent processing drives experience-dependent plasticity for perceptual decisions

    E-pub date: 1 Aug 2020
    Authors: K Jia, E Zamboni, V Kemper, C Rua, N Reis Goncalves, AKT Ng, C Rodgers, G Williams, R Goebel, Z Kourtzi