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EMAIL zk240@cam.ac.uk
College Downing College
Department
  • Psychology
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    Research Theme Adaptive Brain Computations Brains and Machines
    Research Focus

    Keywords

  • Multimodal Neuroimaging
  • Computation

    • Clinical Conditions

  • Dementia

    • Equipment & Techniques

  • Computational modelling
  • Magnetic resonance imaging (MRI)
  • Behavioural analysis

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    Professor Zoe Kourtzi

    University Position
    Professor
    Professor Zoe Kourtzi is pleased to consider applications from prospective PhD students.

    Interests

    Research at the Adaptive Brain Lab is at the interface of Neural and Computational Sciences. Our experimental work aims to understand the role of lifelong learning and brain plasticity in enabling humans of all ages to translate sensory experience into adaptive behaviours. Our computational work aims to develop predictive AI-guided models of neurodegenerative disease and mental health with translational impact in early diagnosis and personalised interventions.

    Associated News Items

    Key Publications

    Robust and interpretable AI-guided marker for early dementia prediction in real-world clinical settings

    DOI: http://doi.org/10.1016/j.eclinm.2024.102725
    Journal: EClinicalMedicine
    E-pub date: 31 Aug 2024
    Authors: LY Lee, D Vaghari, MC Burkhart, P Tino, M Montagnese, Z Li, K Zühlsdorff, J Giorgio, G Williams, E Chong, C Chen, BR Underwood, T Rittman, Z Kourtzi

    Ultra-High Field Imaging of Human Visual Cognition.

    DOI: http://doi.org/10.1146/annurev-vision-111022-123830
    Journal: Annu Rev Vis Sci
    E-pub date: 15 Sep 2023
    Authors: K Jia, R Goebel, Z Kourtzi

    A robust harmonization approach for cognitive data from multiple aging and dementia cohorts.

    DOI: http://doi.org/10.1002/dad2.12453
    Journal: Alzheimers Dement (Amst)
    E-pub date: 1 Aug 2023
    Authors: J Giorgio, A Tanna, M Malpetti, SR White, J Wang, S Baker, S Landau, T Tanaka, C Chen, JB Rowe, J O'Brien, J Fripp, M Breakspear, W Jagust, Z Kourtzi, Alzheimer's Disease Neuroimaging Initiative, Australian Imaging Biomarkers and Lifestyle flagship study

    Learning at your brain’s rhythm: individualized entrainment boosts learning for perceptual decisions.

    DOI: http://doi.org/10.1093/cercor/bhac426
    Journal: Cereb Cortex
    E-pub date: 25 Apr 2023
    Authors: E Michael, LS Covarrubias, V Leong, Z Kourtzi

    Microstructural and neurochemical plasticity mechanisms interact to enhance human perceptual decision-making.

    DOI: http://doi.org/10.1371/journal.pbio.3002029
    Journal: PLoS Biol
    E-pub date: 1 Mar 2023
    Authors: JJ Ziminski, P Frangou, VM Karlaftis, U Emir, Z Kourtzi

    A robust and interpretable machine learning approach using multimodal biological data to predict future pathological tau accumulation.

    DOI: http://doi.org/10.1038/s41467-022-28795-7
    Journal: Nature Communications
    E-pub date: 7 Apr 2022
    Authors: J Giorgio, WJ Jagust, S Baker, SM Landau, P Tino, Z Kourtzi, Alzheimer’s Disease Neuroimaging Initiative

    A protocol for ultra-high field laminar fMRI in the human brain.

    DOI: http://doi.org/10.1016/j.xpro.2021.100415
    Journal: STAR Protoc
    E-pub date: 18 Jun 2021
    Authors: K Jia, E Zamboni, C Rua, NR Goncalves, V Kemper, AKT Ng, CT Rodgers, G Williams, R Goebel, Z Kourtzi

    Predicting future regional tau accumulation in preclinical Alzheimer’s disease

    DOI: http://doi.org/10.1002/alz.039827
    Journal: Alzheimer's & Dementia
    E-pub date: 1 Dec 2020
    Authors: J Giorgio, WJ Jagust, SL Baker, SM Landau, P Tino, Z Kourtzi

    Fine-scale computations for adaptive processing in the human brain.

    DOI: http://doi.org/10.7554/eLife.57637
    Journal: Elife
    E-pub date: 10 Nov 2020
    Authors: E Zamboni, VG Kemper, NR Goncalves, K Jia, VM Karlaftis, SJ Bell, J Giorgio, R Rideaux, R Goebel, Z Kourtzi

    Recurrent Processing Drives Perceptual Plasticity.

    DOI: http://doi.org/10.1016/j.cub.2020.08.016
    Journal: Curr Biol
    E-pub date: 2 Nov 2020
    Authors: K Jia, E Zamboni, V Kemper, C Rua, NR Goncalves, AKT Ng, CT Rodgers, G Williams, R Goebel, Z Kourtzi

    Modelling prognostic trajectories of cognitive decline due to Alzheimer’s disease.

    DOI: http://doi.org/10.1016/j.nicl.2020.102199
    Journal: Neuroimage Clin
    E-pub date: 1 Aug 2020
    Authors: J Giorgio, SM Landau, WJ Jagust, P Tino, Z Kourtzi, Alzheimer's Disease Neuroimaging Initiative

    GABA, not BOLD, reveals dissociable learning-dependent plasticity mechanisms in the human brain.

    DOI: http://doi.org/10.7554/eLife.35854
    Journal: Elife
    E-pub date: 25 Oct 2018
    Authors: P Frangou, M Correia, Z Kourtzi

    Publications

    Study protocol: How does cognitive flexibility relate to other executive functions and learning in healthy young adults?

    DOI: http://doi.org/10.1371/journal.pone.0286208
    Journal: PLoS One
    E-pub date: 1 Aug 2023
    Authors: K Tong, YN Chan, X Cheng, B Cheon, M Ellefson, R Fauziana, S Feng, N Fischer, B Gulyás, N Hoo, D Hung, K Kalaivanan, C Langley, KM Lee, LL Lee, T Lee, I Melani, N Melia, JY Pei, L Raghani, YL Sam, P Seow, J Suckling, YF Tan, CL Teo, R Uchiyama, HS Yap, G Christopoulos, H Hendriks, A Chen, T Robbins, B Sahakian, Z Kourtzi, V Leong, CLIC Phase 1 Consortium

    Predicting incident dementia in cerebral small vessel disease: comparison of machine learning and traditional statistical models.

    DOI: http://doi.org/10.1016/j.cccb.2023.100179
    Journal: Cereb Circ Cogn Behav
    E-pub date: 1 Aug 2023
    Authors: R Li, EL Harshfield, S Bell, M Burkhart, AM Tuladhar, S Hilal, DJ Tozer, FM Chappell, SDJ Makin, JW Lo, JM Wardlaw, F-E de Leeuw, C Chen, Z Kourtzi, HS Markus

    The Early Detection of Neurodegenerative diseases initiative: an international and multidisciplinary effort for transforming the early detection of dementia‐causing diseases

    DOI: http://doi.org/10.1002/alz.062434
    Journal: Alzheimer's & Dementia
    E-pub date: 1 Jun 2023
    Authors: F Marinaro, C Morvan, R Au, S Bond, MC Burkhart, N Carlebach, D Chan, D Delbarre, L Farier, A Lacey, H LaMonica, CL Lancaster, LY Lee, DJ Llewellyn, A Mallon, RN Martins, RM Ardle, CJ Mummery, SL Naismith, M Oldham, S Rainey‐Smith, L Santos, S Slight, N Smith, S Thomas, J Venton, C Tolley, K Whitaker, J Wright, S Wilson, K Wing, J Crawford, P Dagum, C Routledge, Z Walker, R Everson, C Hinds, Z Kourtzi

    GABA and glutamate deficits from frontotemporal lobar degeneration are associated with disinhibition.

    DOI: http://doi.org/10.1093/brain/awaa305
    Journal: Brain
    E-pub date: 5 Dec 2020
    Authors: AG Murley, MA Rouse, PS Jones, R Ye, FH Hezemans, C O'Callaghan, P Frangou, Z Kourtzi, C Rua, TA Carpenter, CT Rodgers, JB Rowe

    A cross‐cohort cognitive composite for tracking changes in pre‐clinical and prodromal Alzheimer’s disease

    DOI: http://doi.org/10.1002/alz.037928
    Journal: Alzheimer's & Dementia
    E-pub date: 1 Dec 2020
    Authors: J Giorgio, A Tanna, WJ Jagust, SL Baker, SM Landau, T Tanaka, CP Chen, A Reilhac, M Malpetti, JB Rowe, JT O'Brien, Z Kourtzi

    Recurrent processing drives experience-dependent plasticity for perceptual decisions

    DOI: http://doi.org/10.1101/2020.04.07.030510
    Journal:
    E-pub date: 1 Aug 2020
    Authors: K Jia, E Zamboni, V Kemper, C Rua, N Reis Goncalves, AKT Ng, C Rodgers, G Williams, R Goebel, Z Kourtzi