Parental history of type 2 diabetes in patients with nonaffective psychosis.

Abstract:

INTRODUCTION: We attempted to replicate two previous studies which found an increased risk of diabetes in the relatives of schizophrenia probands. METHODS: N=34 patients with newly-diagnosed nonaffective psychosis and N=52 non-psychiatric controls were interviewed for parental history of Type 2 diabetes. RESULTS: In a logistic regression model that included multiple potential confounders, psychosis was a significant predictor of Type 2 diabetes in either parent (p