A world-renowned centre for research, the MRC MBU is a vibrant community focused on the involvement of mitochondria and their dysfunction in an ever-increasing range of human diseases. Additional information can be found at www.mrc-mbu.cam.ac.uk.
The Mitochondrial Neurodegeneration group pursues an integrated, multi-disciplinary programme of investigations to understand the homeostatic mechanisms that regulate the integrity of mitochondria and maintain normal neuronal function and survival. The group uses Drosophila and cellular models to elucidate the molecular mechanisms of pathogenesis of various neurodegenerative diseases such as Parkinson’s Disease, Huntington’s Disease and Motor Neuron Disease. We are now expanding our model repertoire to include mouse and human iNeuron models.
The post-holder will lead one or more projects analysing the role of mitochondrial ion handling (mainly, calcium and iron via MCU and CISD1 proteins) in normal physiology and the contribution to neurodegenerative diseases.
More information and applicationPosted on 12/06/2024
