One grant of up to £1.7m is offered to support a five-year programme of translational biomedical research led by an outstanding researcher in the early years of an established research and academic career. The work must include research on patients with a hypothesis based on pre-clinical experimental data. The application must set out a clear strategy defining how the research will translate into benefit for patients and the timescale within which this will take place.
Please note a few points about eligibility, including updates obtained through communication with the funder:
The work set out in the proposal must be a major commitment for the Principal Applicant, comprising at least 50% of their research time. Where the Principal Applicant holds an existing award from another funder, the institution/organisation will need to verify in its letter of support that the terms of that other funding are consistent with the 50%-time commitment required by the Award.
Grants must be led by a single Principal Applicant in the early years of an established research and academic career. Typically, shortlisted candidates have an established a strong track record of independent research, previously supported by competitive, peer-reviewed fellowships such as those offered by Wellcome, MRC or NIHR. However, the Trust is not prescriptive about how the early years of an established research and academic career is defined and recognises that outstanding researchers may not follow a conventional career path, and/or may have had periods away from research for professional or personal reasons.
The award may not be used to meet the salary costs of the applicant, who should be in an institutionally funded post for the duration of the grant.
Please note that the funder has communicated with us that it will accept applications from any eligible applicant so long as the project involves patients and is translational. Therefore, applicants need not be affiliated with the University’s School of Clinical Medicine to apply.
Institutions can only submit one application. Therefore, this call will be managed according to the University’s restricted calls procedure.
To take part in the internal selection process, please submit your application via our online submission form by Monday 27 October 2025 (if asked to log-in use your Raven details; please note that the Form cannot be saved).
Each applicant will need to have the following information ready to complete the online form submission:
Confirmation of the applicant’s eligibility
CV (3 pages maximum). Applicants are advised to consider DORA principles when presenting research outputs.
Summary of the proposed research, focusing in particular on the following (750 words maximum): Why your project would be suitable for translational study; the unmet need which is to be investigated and how the research will meet that need; a clear strategy defining how the research will translate into benefit for patients and the timescale within which this will take place.
A support letter from the Head of the Department/Centre/Institute that will hold the grant, confirming their support for the project and agreement to host the grant
Internal Assessment Criteria:
Please note that the assessment of internal applications will focus on the following core funder criteria:
Candidate: the research must be led by a clearly identified Principal Applicant of outstanding quality in the early years of an established research and academic career.
Quality of the Research Programme: the proposed research must have a justifiable claim to be at the leading edge of international science.
Benefit to Patients: the application must set out a clear strategy defining how the research will translate into benefit for patients and the timescale within which this will take place
Preliminary application deadline: 12:00, 15 December 2025
