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Research Focus

Keywords

  • Neuronal Plasticity
  • Olfaction
  • Dopamine
  • Adult Neurogenesis
  • Sensory Systems
  • Clinical Conditions

  • Other 
  • Equipment & Techniques

  • Electrophysiological recording techniques
  • Immunohistochemistry
  • Behavioural analysis
  • Science Culture

  • Open Access
  • Public Engagement
  • Widening Participation
  • Teaching
  • Equality, Diversity, Inclusion and Wellbeing
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    Dr Elisa Galliano

    (she/her/hers)
    University Position
    Assistant Professor
    Dr Elisa Galliano is pleased to consider applications from prospective PhD students.

    Interests

    Our lab studies neuronal plasticity and its links to behaviour in the mouse olfactory system. Faced with an ever-changing environment, animals must process sensory inputs to produce appropriate behavioural responses. Neuronal plasticity is fundamental to accomplish this but how adaptive control is achieved at the cellular and network level remains poorly defined. Importantly, the way that circuits, such as those in the early olfactory system, respond and adapt to incoming signals needs to be optimized both for learning (e.g., to discriminate strawberry and banana) and also to assure homeostasis and behavioural stability (e.g., maintaining the ability to detect strawberry smell after temporary anosmia). We are also fascinated by dopamine (it’s in the olfactory bulb too!), and by neurons capable of the most striking type of plasticity: the ability to undergo adult neurogenesis.

    Key Publications

    Characterization of Identified Dopaminergic Neurons in the Mouse Forebrain and Midbrain

    DOI: http://doi.org/10.1101/2023.08.29.554772
    Journal:
    E-pub date: 1 Aug 2023
    Authors: MYH Lau, S Gadiwalla, S Jones, E Galliano

    Ten simple rules for aspiring graduate students.

    DOI: http://doi.org/10.1371/journal.pcbi.1009276
    Journal: PLoS Comput Biol
    E-pub date: 31 Aug 2021
    Authors: AI Luppi, CC Newton, L Folsom, E Galliano, R Romero-Garcia

    Brief Sensory Deprivation Triggers Cell Type-Specific Structural and Functional Plasticity in Olfactory Bulb Neurons.

    DOI: http://doi.org/10.1523/JNEUROSCI.1606-20.2020
    Journal: J Neurosci
    E-pub date: 10 Mar 2021
    Authors: E Galliano, C Hahn, LP Browne, P R Villamayor, C Tufo, A Crespo, MS Grubb

    Embryonic and postnatal neurogenesis produce functionally distinct subclasses of dopaminergic neuron

    DOI: http://doi.org/10.1101/196006
    Journal: eLife
    E-pub date: 20 Apr 2018
    Authors: E Galliano, E Franzoni, M Breton, A Chand, D Byrne, V Murthy, M Grubb

    Publications

    Impact of NMDA Receptor Overexpression on Cerebellar Purkinje Cell Activity and Motor Learning.

    DOI: http://doi.org/10.1523/ENEURO.0270-17.2018
    Journal: eNeuro
    E-pub date: 1 Aug 2018
    Authors: E Galliano, M Schonewille, S Peter, M Rutteman, S Houtman, D Jaarsma, FE Hoebeek, CI De Zeeuw

    Editorial: The Olivo-Cerebellar System.

    DOI: http://doi.org/10.3389/fncir.2015.00066
    Journal: Front Neural Circuits
    E-pub date: 1 Aug 2015
    Authors: E D'Angelo, E Galliano, CI De Zeeuw

    Questioning the cerebellar doctrine.

    DOI: http://doi.org/10.1016/B978-0-444-63356-9.00003-0
    Journal:
    E-pub date: 1 Aug 2014
    Authors: E Galliano, CI De Zeeuw

    Anatomical investigation of potential contacts between climbing fibers and cerebellar Golgi cells in the mouse.

    DOI: http://doi.org/10.3389/fncir.2013.00059
    Journal: Front Neural Circuits
    E-pub date: 1 Aug 2013
    Authors: E Galliano, M Baratella, M Sgritta, TJH Ruigrok, ED Haasdijk, FE Hoebeek, E D'Angelo, D Jaarsma, CI De Zeeuw

    Synaptic transmission and plasticity at inputs to murine cerebellar Purkinje cells are largely dispensable for standard nonmotor tasks.

    DOI: http://doi.org/10.1523/JNEUROSCI.1642-13.2013
    Journal: J Neurosci
    E-pub date: 31 Jul 2013
    Authors: E Galliano, J-W Potters, Y Elgersma, W Wisden, SA Kushner, CI De Zeeuw, FE Hoebeek

    Climbing fiber input shapes reciprocity of Purkinje cell firing.

    DOI: http://doi.org/10.1016/j.neuron.2013.03.018
    Journal: Neuron
    E-pub date: 22 May 2013
    Authors: A Badura, M Schonewille, K Voges, E Galliano, N Renier, Z Gao, L Witter, FE Hoebeek, A Chédotal, CI De Zeeuw

    Silencing the majority of cerebellar granule cells uncovers their essential role in motor learning and consolidation.

    DOI: http://doi.org/10.1016/j.celrep.2013.03.023
    Journal: Cell Rep
    E-pub date: 25 Apr 2013
    Authors: E Galliano, Z Gao, M Schonewille, B Todorov, E Simons, AS Pop, E D'Angelo, AMJM van den Maagdenberg, FE Hoebeek, CI De Zeeuw

    Discovery and rediscoveries of Golgi cells.

    DOI: http://doi.org/10.1113/jphysiol.2010.189605
    Journal: J Physiol
    E-pub date: 1 Oct 2010
    Authors: E Galliano, P Mazzarello, E D'Angelo