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Research Focus

Keywords

  • Brain Networks
  • Network Dynamics
  • Dynamic Causal Networks
  • Clinical Conditions

  • Dementia
  • Depressive disorders
  • Autism spectrum condition
  • Equipment & Techniques

  • Computational modelling
  • Magnetic resonance imaging (MRI)
  • Electrophysiological recording techniques
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    Dr Manfred Kitzbichler

    University Position
    Research Associate

    Interests

    Having a physics background, I am applying general concepts to the analysis of brain activation. This involves both fMRI and MEG, resting state as well as task related data. In particular I am interested in understanding the spatio-temporal dynamics in different brain states.

    Collaborators

    Key Publications

    Sexually divergent development of depression-related brain networks during healthy human adolescence.

    DOI: http://doi.org/10.1126/sciadv.abm7825
    Journal: Sci Adv
    E-pub date: 27 May 2022
    Authors: L Dorfschmidt, RA Bethlehem, J Seidlitz, F Váša, SR White, R Romero-García, MG Kitzbichler, AR Aruldass, SE Morgan, IM Goodyer, P Fonagy, PB Jones, RJ Dolan, NSPN Consortium, NA Harrison, PE Vértes, ET Bullmore

    Publications

    Reward-related activation of fronto-striatal regions scaled negatively with C-reactive protein.

    DOI: http://doi.org/10.1017/S0033291725102031
    Journal: Psychol Med
    E-pub date: 10 Oct 2025
    Authors: AR Aruldass, M Kitzbichler, TV Lim, Wellcome Trust Consortium for Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA), J Cavanagh, P Cowen, C Pariante, E Bullmore, N Harrison

    Atypical Brain Aging and Its Association With Working Memory Performance in Major Depressive Disorder.

    DOI: http://doi.org/10.1016/j.bpsc.2024.04.008
    Journal: Biol Psychiatry Cogn Neurosci Neuroimaging
    E-pub date: 31 Aug 2024
    Authors: NCW Ho, RAI Bethlehem, J Seidlitz, N Nogovitsyn, P Metzak, PL Ballester, S Hassel, S Rotzinger, J Poppenk, RW Lam, VH Taylor, R Milev, Lifespan Brain Chart Consortium, ET Bullmore, AF Alexander-Bloch, BN Frey, KL Harkness, J Addington, SH Kennedy, K Dunlop

    Two human brain systems micro-structurally associated with obesity.

    DOI: http://doi.org/10.7554/eLife.85175
    Journal: Elife
    E-pub date: 20 Oct 2023
    Authors: MG Kitzbichler, D Martins, RAI Bethlehem, R Dear, R Romero-Garcia, V Warrier, J Seidlitz, O Dipasquale, F Turkheimer, M Cercignani, ET Bullmore, NA Harrison

    A longitudinal resource for population neuroscience of school-age children and adolescents in China.

    DOI: http://doi.org/10.1038/s41597-023-02377-8
    Journal: Sci Data
    E-pub date: 21 Aug 2023
    Authors: X-R Fan, Y-S Wang, D Chang, N Yang, M-J Rong, Z Zhang, Y He, X Hou, Q Zhou, Z-Q Gong, L-Z Cao, H-M Dong, J-J Nie, L-Z Chen, Q Zhang, J-X Zhang, L Zhang, H-J Li, M Bao, A Chen, J Chen, X Chen, J Ding, X Dong, Y Du, C Feng, T Feng, X Fu, L-K Ge, B Hong, X Hu, W Huang, C Jiang, L Li, Q Li, S Li, X Liu, F Mo, J Qiu, X-Q Su, G-X Wei, Y Wu, H Xia, C-G Yan, Z-X Yan, X Yang, W Zhang, K Zhao, L Zhu, Chinese Color Nest Consortium (CCNC), Lifespan Brain Chart Consortium (LBCC), X-N Zuo

    Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease.

    DOI: http://doi.org/10.1186/s12974-023-02769-y
    Journal: J Neuroinflammation
    E-pub date: 9 Apr 2023
    Authors: M Vicente-Rodríguez, R Mancuso, A Peris-Yague, C Simmons, NIMA Consortium, D Gómez-Nicola, VH Perry, F Turkheimer, S Lovestone, CA Parker, D Cash

    Two human brain systems micro-structurally associated with obesity

    DOI: http://doi.org/10.1101/2022.11.25.517981
    Journal:
    E-pub date: 28 Nov 2022
    Authors: M Kitzbichler, D Martins, RAI Bethlehem, R Dear, R Romero-Garcia, V Warrier, J Seidlitz, O Dipasquale, F Turkheimer, M Cercignani, E Bullmore, N Harrison

    Publisher Correction: Brain charts for the human lifespan.

    DOI: http://doi.org/10.1038/s41586-022-05300-0
    Journal: Nature
    E-pub date: 1 Oct 2022
    Authors: RAI Bethlehem, J Seidlitz, SR White, JW Vogel, KM Anderson, C Adamson, S Adler, GS Alexopoulos, E Anagnostou, A Areces-Gonzalez, DE Astle, B Auyeung, M Ayub, J Bae, G Ball, S Baron-Cohen, R Beare, SA Bedford, V Benegal, F Beyer, J Blangero, M Blesa Cábez, JP Boardman, M Borzage, JF Bosch-Bayard, N Bourke, VD Calhoun, MM Chakravarty, C Chen, C Chertavian, G Chetelat, YS Chong, JH Cole, A Corvin, M Costantino, E Courchesne, F Crivello, VL Cropley, J Crosbie, N Crossley, M Delarue, R Delorme, S Desrivieres, GA Devenyi, MA Di Biase, R Dolan, KA Donald, G Donohoe, K Dunlop, AD Edwards, JT Elison, CT Ellis, JA Elman, L Eyler, DA Fair, E Feczko, PC Fletcher, P Fonagy, CE Franz, L Galan-Garcia, A Gholipour, J Giedd, JH Gilmore, DC Glahn, IM Goodyer, PE Grant, NA Groenewold, FM Gunning, RE Gur, RC Gur, CF Hammill, O Hansson, T Hedden, A Heinz, RN Henson, K Heuer, J Hoare, B Holla, AJ Holmes, R Holt, H Huang, K Im, J Ipser, CR Jack, AP Jackowski, T Jia, KA Johnson, PB Jones, DT Jones, RS Kahn, H Karlsson, L Karlsson, R Kawashima, EA Kelley, S Kern, KW Kim, MG Kitzbichler, WS Kremen, F Lalonde, B Landeau, S Lee, J Lerch, JD Lewis, J Li, W Liao, C Liston, MV Lombardo, J Lv, C Lynch, TT Mallard, M Marcelis, RD Markello, SR Mathias, B Mazoyer, P McGuire, MJ Meaney, A Mechelli, N Medic, B Misic, SE Morgan, D Mothersill, J Nigg, MQW Ong, C Ortinau, R Ossenkoppele, M Ouyang, L Palaniyappan, L Paly, PM Pan, C Pantelis, MM Park, T Paus, Z Pausova, D Paz-Linares, A Pichet Binette, K Pierce, X Qian, J Qiu, A Qiu, A Raznahan, T Rittman, A Rodrigue, CK Rollins, R Romero-Garcia, L Ronan, MD Rosenberg, DH Rowitch, GA Salum, TD Satterthwaite, HL Schaare, RJ Schachar, AP Schultz, G Schumann, M Schöll, D Sharp, RT Shinohara, I Skoog, CD Smyser, RA Sperling, DJ Stein, A Stolicyn, J Suckling, G Sullivan, Y Taki, B Thyreau, R Toro, N Traut, KA Tsvetanov, NB Turk-Browne, JJ Tuulari, C Tzourio, É Vachon-Presseau, MJ Valdes-Sosa, PA Valdes-Sosa, SL Valk, T van Amelsvoort, SN Vandekar, L Vasung, LW Victoria, S Villeneuve, A Villringer, PE Vértes, K Wagstyl, YS Wang, SK Warfield, V Warrier, E Westman, ML Westwater, HC Whalley, AV Witte, N Yang, B Yeo, H Yun, A Zalesky, HJ Zar, A Zettergren, JH Zhou, H Ziauddeen, A Zugman, XN Zuo, 3R-BRAIN, AIBL, Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Repository Without Borders Investigators, CALM Team, Cam-CAN, CCNP, COBRE, cVEDA, ENIGMA Developmental Brain Age Working Group, Developing Human Connectome Project, FinnBrain, Harvard Aging Brain Study, IMAGEN, KNE96, Mayo Clinic Study of Aging, NSPN, POND, PREVENT-AD Research Group, VETSA, ET Bullmore, AF Alexander-Bloch

    Dysconnectivity of a brain functional network was associated with blood inflammatory markers in depression.

    DOI: http://doi.org/10.1016/j.bbi.2021.08.226
    Journal: Brain Behav Immun
    E-pub date: 1 Nov 2021
    Authors: AR Aruldass, MG Kitzbichler, SE Morgan, S Lim, M-E Lynall, L Turner, P Vertes, Wellcome Trust Consortium for Neuroimmunology of Mood Disorders and Alzheimer’s Disease (NIMA), J Cavanagh, P Cowen, CM Pariante, NA Harrison, ET Bullmore

    A Modest Increase in 11C-PK11195-Positron Emission Tomography TSPO Binding in Depression Is Not Associated With Serum C-Reactive Protein or Body Mass Index.

    DOI: http://doi.org/10.1016/j.bpsc.2020.12.017
    Journal: Biol Psychiatry Cogn Neurosci Neuroimaging
    E-pub date: 1 Jul 2021
    Authors: JJ Schubert, M Veronese, TD Fryer, R Manavaki, MG Kitzbichler, MA Nettis, V Mondelli, CM Pariante, ET Bullmore, NIMA Consortium, FE Turkheimer

    A modest increase in 11C-PK11195-PET TSPO binding in depression is not associated with serum C-reactive protein or body mass index

    DOI: http://doi.org/10.1101/2020.06.04.20099556
    Journal:
    E-pub date: 5 Jun 2020
    Authors: J Schubert, M Veronese, T Fryer, R Manavaki, M Kitzbichler, M Nettis, V Mondelli, C Pariante, E Bullmore, F Turkheimer, NIMA Consortium

    Gene transcription profiles associated with inter-modular hubs and connection distance in human functional magnetic resonance imaging networks.

    DOI: http://doi.org/10.1098/rstb.2015.0362
    Journal: Philos Trans R Soc Lond B Biol Sci
    E-pub date: 5 Oct 2016
    Authors: PE Vértes, T Rittman, KJ Whitaker, R Romero-Garcia, F Váša, MG Kitzbichler, K Wagstyl, P Fonagy, RJ Dolan, PB Jones, IM Goodyer, NSPN Consortium, ET Bullmore

    Emergence of rich-club topology and coordinated dynamics in development of hippocampal functional networks in vitro.

    DOI: http://doi.org/10.1523/JNEUROSCI.4259-14.2015
    Journal: J Neurosci
    E-pub date: 8 Apr 2015
    Authors: MS Schroeter, P Charlesworth, MG Kitzbichler, O Paulsen, ET Bullmore

    Functional connectivity and brain networks in schizophrenia.

    DOI: http://doi.org/10.1523/JNEUROSCI.0333-10.2010
    Journal: J Neurosci
    E-pub date: 14 Jul 2010
    Authors: M-E Lynall, DS Bassett, R Kerwin, PJ McKenna, M Kitzbichler, U Muller, E Bullmore