Equipment & Techniques
I am a Race Against Dementia & ARUK fellow at the Cambridge Centre for Frontotemporal Dementia and Related disorders. I am interested in the study of neuropathology, biomarkers and clinical features of neurodegenerative diseases, with special interest in frontotemporal lobar degeneration (FTLD) and Alzheimer's disease (AD). My work focuses on the application of neuroimaging techniques (multi-tracer PET and MRI) to investigate the pathophysiology of neurodegenerative diseases, in order to identify early diagnostic and prognostic markers. As a RAD fellow, I am studying novel clinically viable PET and other biomarkers for inflammation, tau and synaptic loss in FTLD. To this end, I apply longitudinal statistical models and multimodal imaging analyses, with an interdisciplinary approach that integrates imaging and clinical data with fluid markers and post-mortem pathology.