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Research Focus

Keywords

  • Astrocytes
  • Clinical Conditions

  • Parkinson's disease
  • Equipment & Techniques

  • Cell culture
  • Calcium imaging
  • Confocal microscopy
  • Immunohistochemistry
  • Protein purification
  • Randomised control trials
  • Science Culture

  • CamBRAIN
  • Green Neuroscience
  • Open Access
  • Public Engagement
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    Dr Nat Hastings

    (she/her/hers)
    University Position
    Visiting Scientist
    Clinical Research Associate

    Interests

    A translational researcher with a focus on clinical neuroscience and bioengineering. Developing novel small molecules to stabilise astrocytic networks and stop Parkinson's disease and related disorders of the brain marked by inflammation and misfolded protein aggregation.

    In vitro astrocytic network

    A group of cultured astrocytes injected with a gap junction-permeable dye to visualise the network coupling

    Key Publications

    Electrophysiological In Vitro Study of Long-Range Signal Transmission by Astrocytic Networks.

    DOI: http://doi.org/10.1002/advs.202301756
    Journal: Adv Sci (Weinh)
    E-pub date: 1 Oct 2023
    Authors: N Hastings, Y-L Yu, B Huang, S Middya, M Inaoka, NA Erkamp, RJ Mason, A Carnicer-Lombarte, S Rahman, TPJ Knowles, M Bance, GG Malliaras, MRN Kotter

    Publications

    Transcription factor combinations that define human astrocyte identity encode significant variation of maturity and function.

    DOI: http://doi.org/10.1002/glia.24372
    Journal: Glia
    E-pub date: 31 Aug 2023
    Authors: K Baranes, N Hastings, S Rahman, N Poulin, JM Tavares, W-L Kuan, N Syed, M Kunz, K Blighe, TG Belgard, MRN Kotter

    Therapeutic Potential of Astrocyte Transplantation.

    DOI: http://doi.org/10.1177/09636897221105499
    Journal: Cell Transplant
    E-pub date: 1 Aug 2022
    Authors: N Hastings, W-L Kuan, A Osborne, MRN Kotter