Equipment & Techniques
As a cognitive neuroscientist my principal research interest is understanding the pathological cascade of Alzheimer's disease in humans. This is primarily achieved with PET biomarkers of amyloid and tau, but also incorporates MRI and fluid biomarkers. My research uses techniques that include high-resolution neuroimaging and neuropsychological testing with the objective of providing convergent information within the same individuals along the continuum of disease (presymptomatic to manifest dementia). Along with the main PET biomarkers used in dementia research (amyloid-β; tau), I'm also interested in understanding the role astrocytes play in the pathological cascade by using novel PET radiotracers that can measure astrocyte function in vivo.