EMAIL sj251@cam.ac.uk

Department

Physiology, Development and Neuroscience

School

Biological Sciences

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Research Theme Neurons, Circuits and Networks Lifelong Brain Development and Brain Ageing Adaptive Brain Computations

Research Focus

Keywords

Neural Circuits

Equipment & Techniques

Electrophysiological recording techniques

Science Culture

Equality, Diversity, Inclusion and Wellbeing

Open Access

Teaching

Women in Neuroscience

Widening Participation

Reproducibility in Science

Public Engagement

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Dr Susan Jones

(she/her/hers)

University Position

Associate Professor

Interests

My interest is cellular and synaptic neurophysiology and pharmacology in the mammalian brain, and how they contribute to behaviour and neuronal plasticity. I currently work on kisspeptin neurons (in collaboration with Professor Bill Colledge ), involved in sexual and reproductive behaviour, and amygdala neurons (in collaboration with prof David Belin), which are important in plasticity mechanisms in models of substance abuse disorders. I have a long-standing interest in dopaminergic neurons.

Collaborators

Cambridge

William Colledge

David Belin

Elisa Galliano

Key Publications

Sex-Specific Effects of a Maternal Obesogenic Diet High in Fat and Sugar on Offspring Adiposity, Growth, and Behavior

DOI: http://doi.org/10.3390/nu15214594
Journal: Nutrients
E-pub date: 29 Oct 2023
Authors: EJ Mort, S Heritage, S Jones, AL Fowden, EJ Camm

Characterization of Identified Dopaminergic Neurons in the Mouse Forebrain and Midbrain

DOI: http://doi.org/10.1101/2023.08.29.554772
Journal:
E-pub date: 1 Aug 2023
Authors: MYH Lau, S Gadiwalla, S Jones, E Galliano

NR2B- and NR2D-containing synaptic NMDA receptors in developing rat substantia nigra pars compacta dopaminergic neurones.

DOI: http://doi.org/10.1113/jphysiol.2007.144618
Journal: J Physiol
E-pub date: 1 Feb 2008
Authors: SLC Brothwell, JL Barber, DT Monaghan, DE Jane, AJ Gibb, S Jones

Synaptic plasticity and drug addiction.

DOI: http://doi.org/10.1016/j.coph.2004.08.011
Journal: Curr Opin Pharmacol
E-pub date: 1 Feb 2005
Authors: S Jones, A Bonci

Amphetamine blocks long-term synaptic depression in the ventral tegmental area.

DOI: http://doi.org/10.1523/JNEUROSCI.20-15-05575.2000
Journal: J Neurosci
E-pub date: 1 Aug 2000
Authors: S Jones, JL Kornblum, JA Kauer

Nicotinic receptors in the brain: correlating physiology with function.

DOI: http://doi.org/10.1016/s0166-2236(99)01471-x
Journal: Trends Neurosci
E-pub date: 1 Dec 1999
Authors: S Jones, S Sudweeks, JL Yakel

Publications

Age and an obesogenic diet affect mouse behaviour in a sex-dependent manner.

DOI: http://doi.org/10.1111/ejn.16070
Journal: Eur J Neurosci
E-pub date: 1 Jul 2023
Authors: EJ Mort, S Fordington, S Heritage, AL Fowden, S Jones, EJ Camm

De-mobilisation of NMDA receptors in midbrain dopamine neurons: a quantum of reward?

DOI: http://doi.org/10.1113/JP281559
Journal: J Physiol
E-pub date: 1 Jun 2021
Authors: S Jones

A new villain in neuronal death.

DOI: http://doi.org/10.1126/science.abe2791
Journal: Science
E-pub date: 9 Oct 2020
Authors: S Jones

Mapping neuronal inputs to Kiss1 neurons in the arcuate nucleus of the mouse.

DOI: http://doi.org/10.1371/journal.pone.0213927
Journal: PLoS One
E-pub date: 1 Aug 2019
Authors: S-H Yeo, V Kyle, C Blouet, S Jones, WH Colledge

Altered Synaptic and Extrasynaptic NMDA Receptor Properties in Substantia Nigra Dopaminergic Neurons From Mice Lacking the GluN2D Subunit.

DOI: http://doi.org/10.3389/fncel.2018.00354
Journal: Front Cell Neurosci
E-pub date: 1 Aug 2018
Authors: PG Morris, M Mishina, S Jones

Calpain inhibition reduces NMDA receptor rundown in rat substantia nigra dopamine neurons.

DOI: http://doi.org/10.1016/j.neuropharm.2018.05.003
Journal: Neuropharmacology
E-pub date: 15 Jul 2018
Authors: J Zhao, M Baudry, S Jones

Mechanisms regulating spill-over of synaptic glutamate to extrasynaptic NMDA receptors in mouse substantia nigra dopaminergic neurons.

DOI: http://doi.org/10.1111/ejn.13075
Journal: Eur J Neurosci
E-pub date: 1 Nov 2015
Authors: AR Wild, M Bollands, PG Morris, S Jones

Memantine block depends on agonist presentation at the NMDA receptor in substantia nigra pars compacta dopamine neurones.

DOI: http://doi.org/10.1016/j.neuropharm.2013.05.013
Journal: Neuropharmacology
E-pub date: 1 Oct 2013
Authors: AR Wild, E Akyol, SLC Brothwell, P Kimkool, JN Skepper, AJ Gibb, S Jones

Event time representation in cerebellar mossy fibres arising from the lateral reticular nucleus.

DOI: http://doi.org/10.1113/jphysiol.2012.244723
Journal: J Physiol
E-pub date: 15 Feb 2013
Authors: W Xu, S Jones, SA Edgley

Clorgyline-mediated reversal of neurological deficits in a Complexin 2 knockout mouse.

DOI: http://doi.org/10.1093/hmg/ddq252
Journal: Hum Mol Genet
E-pub date: 1 Sep 2010
Authors: D Glynn, HE Gibson, MK Harte, K Reim, S Jones, GP Reynolds, AJ Morton

Functional heterogeneity of NMDA receptors in rat substantia nigra pars compacta and reticulata neurones.

DOI: http://doi.org/10.1111/j.1460-9568.2010.07298.x
Journal: Eur J Neurosci
E-pub date: 31 Aug 2010
Authors: F Suárez, Q Zhao, DT Monaghan, DE Jane, S Jones, AJ Gibb

Functional alpha7-containing nicotinic acetylcholine receptors localize to cell bodies and proximal dendrites in the rat substantia nigra pars reticulata.

DOI: http://doi.org/10.1113/jphysiol.2008.149963
Journal: J Physiol
E-pub date: 1 Mar 2008
Authors: OV Poisik, J-X Shen, S Jones, JL Yakel

Functional NR2B- and NR2D-containing NMDA receptor channels in rat substantia nigra dopaminergic neurones.

DOI: http://doi.org/10.1113/jphysiol.2005.095554
Journal: J Physiol
E-pub date: 15 Nov 2005
Authors: S Jones, AJ Gibb

A similar impairment in CA3 mossy fibre LTP in the R6/2 mouse model of Huntington’s disease and in the complexin II knockout mouse.

DOI: http://doi.org/10.1111/j.1460-9568.2005.04349.x
Journal: Eur J Neurosci
E-pub date: 1 Oct 2005
Authors: HE Gibson, K Reim, N Brose, AJ Morton, S Jones

Rapid synaptic plasticity of glutamatergic synapses on dopamine neurons in the ventral tegmental area in response to acute amphetamine injection.

DOI: http://doi.org/10.1038/sj.npp.1300495
Journal: Neuropsychopharmacology
E-pub date: 1 Dec 2004
Authors: LJ Faleiro, S Jones, JA Kauer

Amphetamine depresses excitatory synaptic transmission via serotonin receptors in the ventral tegmental area.

DOI: http://doi.org/10.1523/JNEUROSCI.19-22-09780.1999
Journal: J Neurosci
E-pub date: 15 Nov 1999
Authors: S Jones, JA Kauer

Ca2+ influx through voltage-gated Ca2+ channels regulates 5-HT3 receptor channel desensitization in rat glioma x mouse neuroblastoma hybrid NG108-15 cells.

DOI: http://doi.org/10.1111/j.1469-7793.1998.361bk.x
Journal: J Physiol
E-pub date: 15 Jul 1998
Authors: S Jones, JL Yakel

Functional nicotinic ACh receptors on interneurones in the rat hippocampus.

DOI: http://doi.org/10.1111/j.1469-7793.1997.603bd.x
Journal: J Physiol
E-pub date: 1 Nov 1997
Authors: S Jones, JL Yakel

Bradykinin excites rat sympathetic neurons by inhibition of M current through a mechanism involving B2 receptors and G alpha q/11.

DOI: http://doi.org/10.1016/0896-6273(95)90295-3
Journal: Neuron
E-pub date: 1 Feb 1995
Authors: S Jones, DA Brown, G Milligan, E Willer, NJ Buckley, MP Caulfield

Muscarinic M‐current inhibition via G alpha q/11 and alpha‐adrenoceptor inhibition of Ca2+ current via G alpha o in rat sympathetic neurones.

DOI: http://doi.org/10.1113/jphysiol.1994.sp020203
Journal: The Journal of Physiology
E-pub date: 15 Jun 1994
Authors: MP Caulfield, S Jones, Y Vallis, NJ Buckley, GD Kim, G Milligan, DA Brown

Zn2+ potentiates ATP-activated currents in rat sympathetic neurons.

DOI: http://doi.org/10.1007/BF00374606
Journal: Pflugers Arch
E-pub date: 1 Jul 1993
Authors: R Cloues, S Jones, DA Brown

Neurotransmitter modulation of calcium channels is dependent on the charge carrier used in the recording of currents.

DOI: http://doi.org/10.1016/0304-3940(92)90009-v
Journal: Neurosci Lett
E-pub date: 12 Oct 1992
Authors: S Jones, J Robbins, DA Brown