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Research Focus

Keywords

  • Structural MRI
  • Diffusion MRI
  • Clinical Conditions

  • Dementia
  • Alzheimer's disease
  • Frontotemporal dementia
  • Progressive supranuclear palsy
  • Lewy body dementia
  • Vascular dementia
  • Equipment & Techniques

  • Magnetic resonance imaging (MRI)
  • Computational modelling
  • Science Culture

  • Open-Source Science
  • Public Engagement
  • Teaching
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    Tatjana Schmidt

    (she/her/hers)
    University Position
    PhD student

    Interests

    I'm a fourth-year PhD student and a systems neuroscientist. My main interest lies in using diffusion MRI to investigate the microstructural correlates of white matter pathology across diseases, with the goal of biophysically informed and clinically useful characterisation of WM changes. Other projects are a transdiagnostic framework in order to classify patients with neurodegenerative disorders based on an ontology of clinical features, and a traveling heads MRI study investigating the reproducibility of advanced dMRI metrics. We aim at translating our findings to memory clinics in order to provide advanced MRI protocols and diagnostic procedures for patients. Other areas of interest apart from dMRI modeling and analysis are open science and reproducibility, as well as teaching and supervising (currently Medical Physics for undergraduates).

    Key Publications

    Automated quantification of white matter hyperintensity confluence: A measure of spatial organisation beyond volume and visual rating scales

    DOI: https://doi.org/10.64898/2026.07.24.740551
    Journal: BioRxiv
    Year: 2026
    Authors: Tatjana V. Schmidt, Robert Salzmann, Marcella Montagnese, Dennis Chan, Jose Bernal, Malte Pfister, Philipp Arndt, Oliver Peters, Julian Hellmann-Regen, Lukas Preis, Daria Gref, Josef Priller, Eike Spruth, Maria Gemenetzi, Slawek Altenstein, Anja Schneider, Klaus Fliessbach, Okka Kimmich, Jens Wiltfang, Claudia Bartels, Bjoern Schott, Ayda Rostamzadeh, Wenzel Glanz, Enise Incesoy, Michaela Butryn, Katharina Buerger, Daniel Janowitz, Sophia Stoecklein, Robert Perneczky, Boris-Stephan Rauchmann, Stefan Teipel, Mihovil Mladinov, Alice Grazia, Christoph Laske, Sebastian Sodenkamp, Annika Spottke, Gabor Petzold, Michael Wagner, Falk Lusebrink, Luca Kleineidam, Stefan Hetzer, Peter Dechent, Stefanie Schreiber, Emrah Duezel, Frank Jessen, Gabriel Ziegler, Benjamin Underwood, Timothy Rittman

    A Road Trip Down Memory Lane: Mapping the Brain’s Pathways With Diffusion MRI

    DOI: https://doi.org/10.3389/frym.2026.1642603
    Journal: Frontiers for Young Minds
    Year: 2026
    Authors: Tatjana Schmidt, Marta Correia

    Estimating demand for potential disease-modifying therapies for Alzheimer's disease in the UK

    DOI: https://doi.org/10.1192/bjp.2023.166
    Journal: The British Journal of Psychiatry
    Year: 2024
    Authors: Axel A. S. Laurell, Ashwin V. Venkataraman , Tatjana Schmidt , Marcella Montagnese , Christoph Mueller, Robert Stewart, Jonathan Lewis , Clare Mundell , Jeremy D. Isaacs, Mani S. Krishnan , Robert Barber, Timothy Rittman, Benjamin R. Underwood

    The quest for the best: manual, atlas- and spatial prior-based delineation of locus coeruleus

    DOI: https://doi-org.ezp.lib.cam.ac.uk/10.1016/j.nicl.2026.104039
    Journal: Neuroimage: Clinical
    Year: 2026
    Authors: Olga Dmitrichenko, Giuseppina Baldizzi, Tatjana Schmidt, Aurélie Bussy, Olivier Colliot, Antoine Lutti, Ferath Kherif, Bogdan Draganski

    Rapid pre-attentive processing of a famous speaker: Electrophysiological effects of Angela Merkel's voice

    DOI: https://doi.org/10.1016/j.neuropsychologia.2022.108312
    Journal: Neuropsychologia
    Year: 2022
    Authors: Paula Rinke, Tatjana Schmidt, Kjartan Beier, Ramona Kaul, Mathias Scharinger

    Publications