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  • Neurology Unit
  • Other Interdiciplinary Incentives

  • Neuroscience
  • Research Focus

    Keywords

  • Dementia
  • Progressive Supranuclear Palsy
  • Frontotemporal Dementia
  • Multimodal Neuroimaging
  • Neuropathology
  • Clinical Conditions

  • Progressive supranuclear palsy
  • Dementia
  • Equipment & Techniques

  • Magnetic resonance imaging (MRI)
  • Science Culture

  • Public Engagement
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    Dr Timothy Rittman

    University Position
    Other
    Dr Timothy Rittman is pleased to consider applications from prospective PhD students.

    Interests

    My interests are to understand neurodegenerative tauopathies at the systems level, and to translate artificial intelligence algorithms into clinical practice for memory clinics.

    Key Publications

    Accurate digital quantification of tau pathology in progressive supranuclear palsy.

    DOI: http://doi.org/10.1186/s40478-023-01674-y
    Journal: Acta Neuropathol Commun
    E-pub date: 9 Nov 2023
    Authors: T Pansuwan, A Quaegebeur, SS Kaalund, E Hidari, M Briggs, JB Rowe, T Rittman

    Understanding ethnic diversity in open dementia neuroimaging datasets

    DOI: http://doi.org/10.1093/braincomms/fcad308
    Journal: Brain Commun
    E-pub date: 1 Aug 2023
    Authors: T Rittman, N Heng

    Identifying healthy individuals with Alzheimer’s disease neuroimaging phenotypes in the UK Biobank.

    DOI: http://doi.org/10.1038/s43856-023-00313-w
    Journal: Commun Med (Lond)
    E-pub date: 20 Jul 2023
    Authors: T Azevedo, RAI Bethlehem, DJ Whiteside, N Swaddiwudhipong, JB Rowe, P Lió, T Rittman, Alzheimer’s Disease Neuroimaging Initiative

    Pre-diagnostic cognitive and functional impairment in multiple sporadic neurodegenerative diseases.

    DOI: http://doi.org/10.1002/alz.12802
    Journal: Alzheimers Dement
    E-pub date: 1 May 2023
    Authors: N Swaddiwudhipong, DJ Whiteside, FH Hezemans, D Street, JB Rowe, T Rittman

    Brain charts for the human lifespan

    DOI: http://doi.org/10.1101/2021.06.08.447489
    Journal:
    E-pub date: 1 Aug 2021
    Authors: RAI Bethlehem, J Seidlitz, SR White, JW Vogel, KM Anderson, C Adamson, S Adler, GS Alexopoulos, E Anagnostou, A Areces-Gonzalez, DE Astle, B Auyeung, M Ayub, G Ball, S Baron-Cohen, R Beare, SA Bedford, V Benegal, F Beyer, J Bin Bae, J Blangero, M Blesa Cábez, JP Boardman, M Borzage, JF Bosch-Bayard, N Bourke, VD Calhoun, MM Chakravarty, C Chen, C Chertavian, G Chetelat, YS Chong, JH Cole, A Corvin, M Costantino, E Courchesne, F Crivello, VL Cropley, J Crosbie, N Crossley, M Delarue, R Delorme, S Desrivieres, G Devenyi, MA Di Biase, R Dolan, KA Donald, G Donohoe, K Dunlop, AD Edwards, JT Elison, CT Ellis, JA Elman, L Eyler, DA Fair, E Feczko, PC Fletcher, P Fonagy, CE Franz, L Galan-Garcia, A Gholipour, J Giedd, JH Gilmore, DC Glahn, I Goodyer, PE Grant, NA Groenewold, FM Gunning, RE Gur, RC Gur, CF Hammill, O Hansson, T Hedden, A Heinz, RN Henson, K Heuer, J Hoare, B Holla, AJ Holmes, R Holt, H Huang, K Im, J Ipser, CR Jack, AP Jackowski, T Jia, KA Johnson, PB Jones, DT Jones, R Kahn, H Karlsson, L Karlsson, R Kawashima, EA Kelley, S Kern, K Kim, MG Kitzbichler, WS Kremen, F Lalonde, B Landeau, S Lee, J Lerch, JD Lewis, J Li, W Liao, C Liston, MV Lombardo, J Lv, C Lynch, TT Mallard, M Marcelis, RD Markello, SR Mathias, B Mazoyer, P McGuire, MJ Meaney, A Mechelli, N Medic, B Misic, SE Morgan, D Mothersill, J Nigg, MQW Ong, C Ortinau, C Ortinau, R Ossenkoppele, M Ouyang, L Palaniyappan, L Paly, PM Pan, C Pantelis, MM Park, T Paus, Z Pausova, D Paz-Linares, A Pichet Binette, K Pierce, X Qian, J Qiu, A Qiu, A Raznahan, T Rittman, A Rodrigue, CK Rollins, R Romero-Garcia, L Ronan, MD Rosenberg, DH Rowitch, GA Salum, TD Satterthwaite, HL Schaare, RJ Schachar, AP Schultz, G Schumann, M Schöll, D Sharp, RT Shinohara, I Skoog, CD Smyser, RA Sperling, DJ Stein, A Stolicyn, J Suckling, G Sullivan, Y Taki, B Thyreau, R Toro, N Traut, KA Tsvetanov, NB Turk-Browne, JJ Tuulari, C Tzourio, É Vachon-Presseau, MJ Valdes-Sosa, PA Valdes-Sosa, SL Valk, T van Amelsvoort, SN Vandekar, L Vasung, LW Victoria, S Villeneuve, A Villringer, A Villringer, PE Vértes, K Wagstyl, YS Wang, SK Warfield, V Warrier, E Westman, ML Westwater, HC Whalley, AV Witte, N Yang, B Yeo, H Yun, A Zalesky, HJ Zar, A Zettergren, JH Zhou, H Ziauddeen, A Zugman, XN Zuo, ET Bullmore, AF Alexander-Bloch, 3R-BRAIN, AIBL, Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Repository Without Borders Investigators, UMN BCP, CALM Team, Cam-CAN, CCNP, COBRE, Developing Human Connectome Project, ENIGMA Developmental Brain Age working group, FinnBrain, Harvard Aging Brain Study, IMAGEN, KNE96, The Mayo Clinic Study of Aging, NSPN, POND, The PREVENT-AD Research Group, VETSA

    Publications

    Differential Synaptic Loss in β‐Amyloid Positive Versus β‐Amyloid Negative Corticobasal Syndrome

    DOI: http://doi.org/10.1002/mds.29814
    Journal: Mov Disord
    E-pub date: 26 Apr 2024
    Authors: N Holland, G Savulich, PS Jones, DJ Whiteside, D Street, P Swann, M Naessens, M Malpetti, YT Hong, TD Fryer, T Rittman, E Mulroy, FI Aigbirhio, KP Bhatia, JT O'Brien, JB Rowe

    Synaptic density affects clinical severity via network dysfunction in syndromes associated with frontotemporal lobar degeneration.

    DOI: http://doi.org/10.1038/s41467-023-44307-7
    Journal: Nat Commun
    E-pub date: 20 Dec 2023
    Authors: DJ Whiteside, N Holland, KA Tsvetanov, E Mak, M Malpetti, G Savulich, PS Jones, M Naessens, MA Rouse, TD Fryer, YT Hong, FI Aigbirhio, E Mulroy, KP Bhatia, T Rittman, JT O'Brien, JB Rowe

    Artificial intelligence for diagnostic and prognostic neuroimaging in dementia: A systematic review.

    DOI: http://doi.org/10.1002/alz.13412
    Journal: Alzheimers Dement
    E-pub date: 1 Dec 2023
    Authors: RJ Borchert, T Azevedo, A Badhwar, J Bernal, M Betts, R Bruffaerts, MC Burkhart, I Dewachter, HM Gellersen, A Low, I Lourida, L Machado, CR Madan, M Malpetti, J Mejia, S Michopoulou, C Muñoz-Neira, J Pepys, M Peres, V Phillips, S Ramanan, S Tamburin, HM Tantiangco, L Thakur, A Tomassini, A Vipin, E Tang, D Newby, Deep Dementia Phenotyping (DEMON) Network, JM Ranson, DJ Llewellyn, M Veldsman, T Rittman

    Artificial intelligence for biomarker discovery in Alzheimer’s disease and dementia.

    DOI: http://doi.org/10.1002/alz.13390
    Journal: Alzheimers Dement
    E-pub date: 1 Dec 2023
    Authors: LM Winchester, EL Harshfield, L Shi, A Badhwar, AA Khleifat, N Clarke, A Dehsarvi, I Lengyel, I Lourida, CR Madan, SJ Marzi, P Proitsi, AP Rajkumar, T Rittman, E Silajdžić, S Tamburin, JM Ranson, DJ Llewellyn

    Structural correlates of survival in progressive supranuclear palsy.

    DOI: http://doi.org/10.1016/j.parkreldis.2023.105866
    Journal: Parkinsonism Relat Disord
    E-pub date: 1 Nov 2023
    Authors: D Street, WR Bevan-Jones, M Malpetti, PS Jones, L Passamonti, BC Ghosh, T Rittman, IT Coyle-Gilchrist, K Allinson, CE Dawson, JB Rowe

    Network connectivity and structural correlates of survival in progressive supranuclear palsy and corticobasal syndrome.

    DOI: http://doi.org/10.1002/hbm.26342
    Journal: Hum Brain Mapp
    E-pub date: 1 Aug 2023
    Authors: DJ Whiteside, D Street, AG Murley, PS Jones, M Malpetti, BCP Ghosh, I Coyle-Gilchrist, A Gerhard, MT Hu, JC Klein, PN Leigh, A Church, DJ Burn, HR Morris, JB Rowe, T Rittman

    Microglial activation in the frontal cortex predicts cognitive decline in frontotemporal dementia.

    DOI: http://doi.org/10.1093/brain/awad078
    Journal: Brain
    E-pub date: 1 Aug 2023
    Authors: M Malpetti, TE Cope, D Street, PS Jones, FH Hezemans, E Mak, KA Tsvetanov, T Rittman, WR Bevan-Jones, K Patterson, L Passamonti, TD Fryer, YT Hong, FI Aigbirhio, JT O'Brien, JB Rowe

    Progression of atypical parkinsonian syndromes: PROSPECT-M-UK study implications for clinical trials.

    DOI: http://doi.org/10.1093/brain/awad105
    Journal: Brain
    E-pub date: 1 Aug 2023
    Authors: D Street, E Jabbari, A Costantini, PS Jones, N Holland, T Rittman, MT Jensen, V Chelban, YY Goh, T Guo, AJ Heslegrave, F Roncaroli, JC Klein, O Ansorge, KSJ Allinson, Z Jaunmuktane, T Revesz, TT Warner, AJ Lees, H Zetterberg, LL Russell, M Bocchetta, JD Rohrer, DJ Burn, N Pavese, A Gerhard, C Kobylecki, PN Leigh, A Church, MTM Hu, H Houlden, H Morris, JB Rowe

    Longitudinal Synaptic Loss in Primary Tauopathies: An In Vivo [11 C]UCB-J Positron Emission Tomography Study.

    DOI: http://doi.org/10.1002/mds.29421
    Journal: Mov Disord
    E-pub date: 1 Jul 2023
    Authors: N Holland, PS Jones, G Savulich, M Naessens, M Malpetti, DJ Whiteside, D Street, P Swann, YT Hong, TD Fryer, T Rittman, E Mulroy, FI Aigbirhio, KP Bhatia, JT O'Brien, JB Rowe

    Temporal dynamics predict symptom onset and cognitive decline in familial frontotemporal dementia.

    DOI: http://doi.org/10.1002/alz.12824
    Journal: Alzheimers Dement
    E-pub date: 1 May 2023
    Authors: DJ Whiteside, M Malpetti, PS Jones, BCP Ghosh, I Coyle-Gilchrist, JC van Swieten, H Seelaar, L Jiskoot, B Borroni, R Sanchez-Valle, F Moreno, R Laforce, C Graff, M Synofzik, D Galimberti, M Masellis, MC Tartaglia, E Finger, R Vandenberghe, A de Mendonça, F Tagliavini, CR Butler, I Santana, IL Ber, A Gerhard, S Ducharme, J Levin, A Danek, M Otto, S Sorbi, F Pasquier, A Bouzigues, LL Russell, JD Rohrer, JB Rowe, T Rittman, GENFI consortium

    Harnessing the potential of machine learning and artificial intelligence for dementia research.

    DOI: http://doi.org/10.1186/s40708-022-00183-3
    Journal: Brain Inform
    E-pub date: 24 Feb 2023
    Authors: JM Ranson, M Bucholc, D Lyall, D Newby, L Winchester, NP Oxtoby, M Veldsman, T Rittman, S Marzi, N Skene, A Al Khleifat, IF Foote, V Orgeta, A Kormilitzin, I Lourida, DJ Llewellyn

    Synaptic Loss in Frontotemporal Dementia Revealed by [11 C]UCB-J Positron Emission Tomography.

    DOI: http://doi.org/10.1002/ana.26543
    Journal: Ann Neurol
    E-pub date: 1 Jan 2023
    Authors: M Malpetti, PS Jones, TE Cope, N Holland, M Naessens, MA Rouse, T Rittman, G Savulich, DJ Whiteside, D Street, TD Fryer, YT Hong, S Milicevic Sephton, FI Aigbirhio, JT O Brien, JB Rowe

    Ocular Biomarkers for Alzheimer Disease Dementia: An Umbrella Review of Systematic Reviews and Meta-analyses.

    DOI: http://doi.org/10.1001/jamaophthalmol.2022.4845
    Journal: JAMA Ophthalmol
    E-pub date: 1 Jan 2023
    Authors: E Costanzo, I Lengyel, M Parravano, I Biagini, M Veldsman, A Badhwar, M Betts, A Cherubini, DJ Llewellyn, I Lourida, T MacGillivray, T Rittman, S Tamburin, XY Tai, G Virgili

    A modified Camel and Cactus Test detects presymptomatic semantic impairment in genetic frontotemporal dementia within the GENFI cohort.

    DOI: http://doi.org/10.1080/23279095.2020.1716357
    Journal: Appl Neuropsychol Adult
    E-pub date: 1 Aug 2022
    Authors: K Moore, R Convery, M Bocchetta, M Neason, DM Cash, C Greaves, LL Russell, MTM Clarke, G Peakman, J van Swieten, L Jiskoot, F Moreno, M Barandiaran, R Sanchez-Valle, B Borroni, R Laforce, M-C Doré, M Masellis, MC Tartaglia, C Graff, D Galimberti, JB Rowe, E Finger, M Synofzik, H-O Karnath, R Vandenberghe, A de Mendonça, C Maruta, F Tagliavini, I Santana, S Ducharme, C Butler, A Gerhard, J Levin, A Danek, M Otto, JD Warren, JD Rohrer, Genetic FTD Initiative, GENFI*

    The Emerging Role of AI in Dementia Research and Healthcare

    DOI: http://doi.org/10.1007/978-981-19-5272-2_4
    Journal:
    E-pub date: 1 Aug 2022
    Authors: JM Ranson, M Bucholc, D Lyall, D Newby, L Winchester, N Oxtoby, M Veldsman, T Rittman, S Marzi, N Skene, A Al Khleifat, I Foote, V Orgeta, A Kormilitzin, DJ Llewellyn

    Pre-Diagnostic Cognitive and Functional Impairment in Multiple Sporadic Neurodegenerative Diseases

    DOI: http://doi.org/10.1101/2022.04.05.22273468
    Journal:
    E-pub date: 1 Aug 2022
    Authors: N Swaddiwudhipong, D Whiteside, F Hezemans, D Street, J Rowe, T Rittman

    In Vivo 18F-Flortaucipir PET Does Not Accurately Support the Staging of Progressive Supranuclear Palsy.

    DOI: http://doi.org/10.2967/jnumed.121.262985
    Journal: J Nucl Med
    E-pub date: 1 Jul 2022
    Authors: M Malpetti, SS Kaalund, KA Tsvetanov, T Rittman, M Briggs, KSJ Allinson, L Passamonti, N Holland, PS Jones, TD Fryer, YT Hong, A Kouli, WR Bevan-Jones, E Mak, G Savulich, MG Spillantini, FI Aigbirhio, CH Williams-Gray, JT O'Brien, JB Rowe

    Atomoxetine and citalopram alter brain network organisation in Parkinson’s disease

    DOI: http://doi.org/10.1136/jnnp-2022-abn.18
    Journal: Journal of Neurology, Neurosurgery & Psychiatry
    E-pub date: 1 Jun 2022
    Authors: R Borchert, T Rittman, C Rae, L Passamonti, S Jones, D Vatansever, PVZ Rodríguez, Z Ye, J Rowe

    Brain charts for the human lifespan

    DOI: http://doi.org/10.1038/s41586-022-04554-y
    Journal: Nature
    E-pub date: 6 Apr 2022
    Authors: RAI Bethlehem, J Seidlitz, SR White, JW Vogel, KM Anderson, C Adamson, S Adler, GS Alexopoulos, E Anagnostou, A Areces-Gonzalez, DE Astle, B Auyeung, M Ayub, G Ball, S Baron-Cohen, R Beare, SA Bedford, V Benegal, F Beyer, J Bin Bae, J Blangero, M Blesa Cábez, JP Boardman, M Borzage, JF Bosch-Bayard, N Bourke, VD Calhoun, MM Chakravarty, C Chen, C Chertavian, G Chetelat, YS Chong, JH Cole, A Corvin, E Courchesne, F Crivello, VL Cropley, J Crosbie, N Crossley, M Delarue, S Desrivieres, G Devenyi, MA Di Biase, R Dolan, KA Donald, G Donohoe, K Dunlop, AD Edwards, JT Elison, CT Ellis, JA Elman, L Eyler, DA Fair, PC Fletcher, P Fonagy, CE Franz, L Galan-Garcia, A Gholipour, J Giedd, JH Gilmore, DC Glahn, I Goodyer, PE Grant, NA Groenewold, FM Gunning, RE Gur, RC Gur, CF Hammill, O Hansson, T Hedden, A Heinz, R Henson, K Heuer, J Hoare, B Holla, AJ Holmes, R Holt, H Huang, K Im, J Ipser, CR Jack, AP Jackowski, T Jia, KA Johnson, PB Jones, DT Jones, R Kahn, H Karlsson, L Karlsson, R Kawashima, EA Kelley, S Kern, K Kim, MG Kitzbichler, WS Kremen, F Lalonde, B Landeau, S Lee, J Lerch, JD Lewis, J Li, W Liao, DP Linares, C Liston, MV Lombardo, J Lv, C Lynch, TT Mallard, M Marcelis, RD Markello, B Mazoyer, P McGuire, MJ Meaney, A Mechelli, N Medic, B Misic, SE Morgan, D Mothersill, J Nigg, MQW Ong, C Ortinau, R Ossenkoppele, M Ouyang, L Palaniyappan, L Paly, PM Pan, C Pantelis, MM Park, T Paus, Z Pausova, A Pichet Binette, K Pierce, X Qian, J Qiu, A Qiu, A Raznahan, T Rittman, CK Rollins, R Romero-Garcia, L Ronan, MD Rosenberg, DH Rowitch, GA Salum, TD Satterthwaite, HL Schaare, RJ Schachar, AP Schultz, G Schumann, M Schöll, D Sharp, RT Shinohara, I Skoog, CD Smyser, RA Sperling, DJ Stein, A Stolicyn, J Suckling, G Sullivan, Y Taki, B Thyreau, R Toro, KA Tsvetanov, NB Turk-Browne, JJ Tuulari, C Tzourio, É Vachon-Presseau, MJ Valdes-Sosa, PA Valdes-Sosa, SL Valk, T van Amelsvoort, SN Vandekar, L Vasung, LW Victoria, S Villeneuve, A Villringer, PE Vértes, K Wagstyl, YS Wang, SK Warfield, V Warrier, E Westman, ML Westwater, HC Whalley, AV Witte, N Yang, BTT Yeo, HJ Yun, A Zalesky, HJ Zar, A Zettergren, JH Zhou, H Ziauddeen, A Zugman, XN Zuo, AF Alexander-Bloch, AIBL, Alzheimer’s Disease Neuroimaging Initiative, Alzheimer’s Disease Repository Without Borders Investigators, ASRB, CALM Team, Cam-CAN, CCNP, 3R-BRAIN, COBRE, ENIGMA Developmental Brain Age working group, FinnBrain, Harvard Aging Brain Study, IMAGEN, KNE96, NSPN, OASIS-3, OpenPain Project, POND, The PREVENT-AD Research Group, VETSA, Bullmore, E.T

    Regional Radiomics Similarity Networks Reveal Distinct Subtypes and Abnormality Patterns in Mild Cognitive Impairment (Adv. Sci. 12/2022)

    DOI: http://doi.org/10.1002/advs.202270073
    Journal: Advanced Science
    E-pub date: 1 Apr 2022
    Authors: K Zhao, Q Zheng, M Dyrba, T Rittman, A Li, T Che, P Chen, Y Sun, X Kang, Q Li, B Liu, Y Liu, S Li

    Molecular pathology and synaptic loss in primary tauopathies: A [18F]AV-1451 and [11C]UCB-J PET study

    DOI: http://doi.org/10.1093/brain/awab282
    Journal: Brain
    E-pub date: 29 Mar 2022
    Authors: N Holland, M Malpetti, T Rittman, E Mak, L Passamonti, S Kaalund, F Hezemans, P Jones, G Savulich, Y Hong, T Fryer, F Aigbirhio, J O'Brien, J Rowe

    Rate‐limiting processes of tau aggregate accumulation in Alzheimer’s disease

    DOI: http://doi.org/10.1002/alz.051680
    Journal: Alzheimer's & Dementia
    E-pub date: 1 Dec 2021
    Authors: G Meisl, Y Zuo, K Allinson, T Rittman, SL DeVos, JS Sanchez, CK Xu, KE Duff, KA Johnson, JB Rowe, BT Hyman, T Knowles, D Klenerman

    Microglial activation and atrophy in frontal cortex predict executive dysfunction in frontotemporal dementia

    DOI: http://doi.org/10.1002/alz.055456
    Journal: Alzheimer's & Dementia
    E-pub date: 1 Dec 2021
    Authors: M Malpetti, PS Jones, FH Hezemans, E Mak, D Street, L Passamonti, T Rittman, TE Cope, WR Bevan‐Jones, K Patterson, TD Fryer, YT Hong, FI Aigbirho, JT O'Brien, JB Rowe

    Co-Occurrence of Apathy and Impulsivity in Progressive Supranuclear Palsy.

    DOI: http://doi.org/10.1002/mdc3.13339
    Journal: Mov Disord Clin Pract
    E-pub date: 1 Nov 2021
    Authors: ZQ Kok, AG Murley, T Rittman, J Rowe, L Passamonti

    Altered network stability in progressive supranuclear palsy.

    DOI: http://doi.org/10.1016/j.neurobiolaging.2021.07.007
    Journal: Neurobiol Aging
    E-pub date: 1 Nov 2021
    Authors: DJ Whiteside, PS Jones, BCP Ghosh, I Coyle-Gilchrist, A Gerhard, MT Hu, JC Klein, PN Leigh, A Church, DJ Burn, HR Morris, JB Rowe, T Rittman

    In vivo rate-determining steps of tau seed accumulation in Alzheimer’s disease.

    DOI: http://doi.org/10.1126/sciadv.abh1448
    Journal: Sci Adv
    E-pub date: 29 Oct 2021
    Authors: G Meisl, E Hidari, K Allinson, T Rittman, SL DeVos, JS Sanchez, CK Xu, KE Duff, KA Johnson, JB Rowe, BT Hyman, TPJ Knowles, D Klenerman

    Modifiable risk factors for dementia and dementia risk profiling. A user manual for Brain Health Services-part 2 of 6.

    DOI: http://doi.org/10.1186/s13195-021-00895-4
    Journal: Alzheimers Res Ther
    E-pub date: 11 Oct 2021
    Authors: JM Ranson, T Rittman, S Hayat, C Brayne, F Jessen, K Blennow, C van Duijn, F Barkhof, E Tang, CJ Mummery, BCM Stephan, D Altomare, GB Frisoni, F Ribaldi, JL Molinuevo, P Scheltens, DJ Llewellyn, European Task Force for Brain Health Services

    Altered structural connectivity networks in dementia with lewy bodies.

    DOI: http://doi.org/10.1007/s11682-020-00444-x
    Journal: Brain Imaging Behav
    E-pub date: 1 Oct 2021
    Authors: N Nicastro, E Mak, A Surendranathan, T Rittman, JB Rowe, JT O'Brien

    Progressive supranuclear palsy: diagnosis and management.

    DOI: http://doi.org/10.1136/practneurol-2020-002794
    Journal: Pract Neurol
    E-pub date: 1 Oct 2021
    Authors: JB Rowe, N Holland, T Rittman

    Clinical progression of progressive supranuclear palsy: impact of trials bias and phenotype variants.

    DOI: http://doi.org/10.1093/braincomms/fcab206
    Journal: Brain Commun
    E-pub date: 1 Aug 2021
    Authors: D Street, M Malpetti, T Rittman, BCP Ghosh, AG Murley, I Coyle-Gilchrist, L Passamonti, JB Rowe

    Artificial intelligence for diagnosis and prognosis in neuroimaging for dementia; a systematic review

    DOI: http://doi.org/10.1101/2021.12.12.21267677
    Journal:
    E-pub date: 1 Aug 2021
    Authors: R Borchert, T Azevedo, A Badhwar, J Bernal, M Betts, R Bruffaerts, MC Burkhart, I Dewachter, HM Gellersen, A Low, L Machado, CR Madan, M Malpetti, J Mejia, S Michopoulou, C Muñoz-Neira, M Peres, V Phillips, S Ramanan, S Tamburin, H Tantiangco, L Thakur, A Tomassini, A Vipin, E Tang, D Newby, J Ranson, DJ Llewellyn, M Veldsman, T Rittman

    Disease-related cortical thinning in presymptomatic granulin mutation carriers.

    DOI: http://doi.org/10.1016/j.nicl.2020.102540
    Journal: Neuroimage Clin
    E-pub date: 1 Aug 2021
    Authors: S Borrego-Écija, R Sala-Llonch, J van Swieten, B Borroni, F Moreno, M Masellis, C Tartaglia, C Graff, D Galimberti, R Laforce, JB Rowe, E Finger, R Vandenberghe, F Tagliavini, A de Mendonça, I Santana, M Synofzik, S Ducharme, J Levin, A Danek, A Gerhard, M Otto, C Butler, G Frisoni, S Sorbi, C Heller, M Bocchetta, DM Cash, RS Convery, KM Moore, JD Rohrer, R Sanchez-Valle, Genetic FTD Initiative GENFI

    Differential early subcortical involvement in genetic FTD within the GENFI cohort.

    DOI: http://doi.org/10.1016/j.nicl.2021.102646
    Journal: Neuroimage Clin
    E-pub date: 1 Aug 2021
    Authors: M Bocchetta, EG Todd, G Peakman, DM Cash, RS Convery, LL Russell, DL Thomas, J Eugenio Iglesias, JC van Swieten, LC Jiskoot, H Seelaar, B Borroni, D Galimberti, R Sanchez-Valle, R Laforce, F Moreno, M Synofzik, C Graff, M Masellis, M Carmela Tartaglia, JB Rowe, R Vandenberghe, E Finger, F Tagliavini, A de Mendonça, I Santana, CR Butler, S Ducharme, A Gerhard, A Danek, J Levin, M Otto, S Sorbi, I Le Ber, F Pasquier, JD Rohrer, Genetic Frontotemporal dementia Initiative (GENFI)

    Prodromal Progressive Supranuclear Palsy: insights from the UK Biobank

    DOI: http://doi.org/10.1101/2021.05.06.21256759
    Journal:
    E-pub date: 1 Aug 2021
    Authors: D Street, D Whiteside, T Rittman, J Rowe

    Co-occurrence of apathy and impulsivity in progressive supranuclear palsy

    DOI: http://doi.org/10.1101/2021.02.26.21252350
    Journal:
    E-pub date: 1 Aug 2021
    Authors: ZQ Kok, A Murley, T Rittman, J Rowe, L Passamonti

    Impairment of episodic memory in genetic frontotemporal dementia: A GENFI study.

    DOI: http://doi.org/10.1002/dad2.12185
    Journal: Alzheimers Dement (Amst)
    E-pub date: 1 Aug 2021
    Authors: JM Poos, LL Russell, G Peakman, M Bocchetta, CV Greaves, LC Jiskoot, EL van der Ende, H Seelaar, JM Papma, E van den Berg, YAL Pijnenburg, B Borroni, R Sanchez-Valle, F Moreno, R Laforce, C Graff, M Synofzik, D Galimberti, JB Rowe, M Masellis, C Tartaglia, E Finger, R Vandenberghe, A de Medonça, F Tagliavini, CR Butler, I Santana, IL Ber, A Gerhard, S Ducharme, J Levin, A Danek, M Otto, S Sorbi, F Pasquier, JC van Swieten, JD Rohrer, Genetic FTD Initiative, GENF

    Neuroinflammation predicts disease progression in progressive supranuclear palsy.

    DOI: http://doi.org/10.1136/jnnp-2020-325549
    Journal: J Neurol Neurosurg Psychiatry
    E-pub date: 1 Jul 2021
    Authors: M Malpetti, L Passamonti, PS Jones, D Street, T Rittman, TD Fryer, YT Hong, P Vàsquez Rodriguez, WR Bevan-Jones, FI Aigbirhio, JT O'Brien, JB Rowe

    Synaptic density in carriers of C9orf72 mutations: a [11 C]UCB-J PET study.

    DOI: http://doi.org/10.1002/acn3.51407
    Journal: Ann Clin Transl Neurol
    E-pub date: 1 Jul 2021
    Authors: M Malpetti, N Holland, PS Jones, R Ye, TE Cope, TD Fryer, YT Hong, G Savulich, T Rittman, L Passamonti, E Mak, FI Aigbirhio, JT O'Brien, JB Rowe

    Apathy in presymptomatic genetic frontotemporal dementia predicts cognitive decline and is driven by structural brain changes.

    DOI: http://doi.org/10.1002/alz.12252
    Journal: Alzheimers Dement
    E-pub date: 1 Jun 2021
    Authors: M Malpetti, PS Jones, KA Tsvetanov, T Rittman, JC van Swieten, B Borroni, R Sanchez-Valle, F Moreno, R Laforce, C Graff, M Synofzik, D Galimberti, M Masellis, MC Tartaglia, E Finger, R Vandenberghe, A de Mendonça, F Tagliavini, I Santana, S Ducharme, CR Butler, A Gerhard, J Levin, A Danek, M Otto, GB Frisoni, R Ghidoni, S Sorbi, C Heller, EG Todd, M Bocchetta, DM Cash, RS Convery, G Peakman, KM Moore, JD Rohrer, RA Kievit, JB Rowe, Genetic FTD Initiative (GENFI)

    In vivo coupling of dendritic complexity with presynaptic density in primary tauopathies.

    DOI: http://doi.org/10.1016/j.neurobiolaging.2021.01.016
    Journal: Neurobiol Aging
    E-pub date: 1 May 2021
    Authors: E Mak, N Holland, PS Jones, G Savulich, A Low, M Malpetti, SS Kaalund, L Passamonti, T Rittman, R Romero-Garcia, R Manavaki, GB Williams, YT Hong, TD Fryer, FI Aigbirhio, JT O'Brien, JB Rowe

    In vivo PET imaging of neuroinflammation in familial frontotemporal dementia.

    DOI: http://doi.org/10.1136/jnnp-2020-323698
    Journal: J Neurol Neurosurg Psychiatry
    E-pub date: 1 Mar 2021
    Authors: M Malpetti, T Rittman, PS Jones, TE Cope, L Passamonti, WR Bevan-Jones, K Patterson, TD Fryer, YT Hong, FI Aigbirhio, JT O'Brien, JB Rowe

    Brain functional network integrity sustains cognitive function despite atrophy in presymptomatic genetic frontotemporal dementia.

    DOI: http://doi.org/10.1002/alz.12209
    Journal: Alzheimers Dement
    E-pub date: 1 Mar 2021
    Authors: KA Tsvetanov, S Gazzina, PS Jones, J van Swieten, B Borroni, R Sanchez-Valle, F Moreno, R Laforce, C Graff, M Synofzik, D Galimberti, M Masellis, MC Tartaglia, E Finger, R Vandenberghe, A de Mendonça, F Tagliavini, I Santana, S Ducharme, C Butler, A Gerhard, A Danek, J Levin, M Otto, G Frisoni, R Ghidoni, S Sorbi, JD Rohrer, JB Rowe, Genetic FTD Initiative, GENFI

    Neuroinflammation and Tau Colocalize in vivo in Progressive Supranuclear Palsy.

    DOI: http://doi.org/10.1002/ana.25911
    Journal: Ann Neurol
    E-pub date: 1 Dec 2020
    Authors: M Malpetti, L Passamonti, T Rittman, PS Jones, P Vázquez Rodríguez, WR Bevan-Jones, YT Hong, TD Fryer, FI Aigbirhio, JT O'Brien, JB Rowe

    Social cognition impairment in genetic frontotemporal dementia within the GENFI cohort.

    DOI: http://doi.org/10.1016/j.cortex.2020.08.023
    Journal: Cortex
    E-pub date: 1 Dec 2020
    Authors: LL Russell, CV Greaves, M Bocchetta, J Nicholas, RS Convery, K Moore, DM Cash, J van Swieten, L Jiskoot, F Moreno, R Sanchez-Valle, B Borroni, R Laforce, M Masellis, MC Tartaglia, C Graff, E Rotondo, D Galimberti, JB Rowe, E Finger, M Synofzik, R Vandenberghe, A de Mendonça, F Tagliavini, I Santana, S Ducharme, C Butler, A Gerhard, J Levin, A Danek, M Otto, JD Warren, JD Rohrer, Genetic FTD Initiative, GENFI

    Multimodal imaging markers of tau, neuroinflammation and atrophy to predict clinical progression in progressive supranuclear palsy

    DOI: http://doi.org/10.1002/alz.044724
    Journal: Alzheimer's & Dementia
    E-pub date: 1 Dec 2020
    Authors: M Malpetti, L Passamonti, PS Jones, T Rittman, TD Fryer, YT Hong, D Street, PV Rodríguez, WR Bevan‐Jones, FI Aigbirhio, JT O'Brien, JB Rowe

    The prognostic role of microglia and tau PET in Alzheimer’s disease

    DOI: http://doi.org/10.1002/alz.039817
    Journal: Alzheimer's & Dementia
    E-pub date: 1 Dec 2020
    Authors: M Malpetti, RA Kievit, L Passamonti, PS Jones, KA Tsvetanov, T Rittman, E Mak, N Nicastro, WR Bevan‐Jones, L Su, YT Hong, TD Fryer, FI Aigbirho, JT O'Brien, JB Rowe

    Trajectory of apathy, cognition and neural correlates in the decades before symptoms in frontotemporal dementia

    DOI: http://doi.org/10.1002/alz.041821
    Journal: Alzheimer's & Dementia
    E-pub date: 1 Dec 2020
    Authors: M Malpetti, RA Kievit, PS Jones, T Rittman, KA Tsvetanov, JC van Swieten, B Borroni, D Galimberti, R Sanchez‐Valle, R Laforce, F Moreno, M Synofzik, C Graff, M Masellis, C Tartaglia, R Vandenberghe, E Finger, F Tagliavini, A de Mendonca, I Santana, C Butler, S Ducharme, A Gerhard, A Danek, J Levin, M Otto, GB Frisoni, R Ghidoni, C Heller, E Todd, M Bocchetta, RS Convery, G Peakman, KM Moore, JD Rohrer, JB Rowe

    Neurological update: neuroimaging in dementia.

    DOI: http://doi.org/10.1007/s00415-020-10040-0
    Journal: J Neurol
    E-pub date: 1 Nov 2020
    Authors: T Rittman

    In vivo coupling of dendritic complexity with presynaptic density in primary tauopathies

    DOI: http://doi.org/10.1101/2020.12.24.20248838
    Journal:
    E-pub date: 1 Aug 2020
    Authors: E Mak, N Holland, S Jones, G Savulich, A Low, M Malpetti, S Kaalund, L Passamonti, T Rittman, R Romero-Garcia, R Manavaki, G Williams, Y Hong, T Fryer, F Aigbirhio, J O’Brien, J Rowe

    In vivo PET imaging of neuroinflammation in familial frontotemporal dementia

    DOI: http://doi.org/10.1101/2020.05.11.20098046
    Journal:
    E-pub date: 1 Aug 2020
    Authors: M Malpetti, T Rittman, S Jones, T Cope, L Passamonti, R Bevan-Jones, K Patterson, T Fryer, Y Hong, F Aigbirhio, J O’Brien, J Rowe

    Neuroinflammation predicts disease progression in progressive supranuclear palsy

    DOI: http://doi.org/10.1101/2020.05.19.20106393
    Journal:
    E-pub date: 1 Aug 2020
    Authors: M Malpetti, L Passamonti, S Jones, D Street, T Rittman, T Fryer, Y Hong, P Vasquez-Rodriguez, WR Bevan-Jones, F Aigbirhio, J O'Brien, J Rowe

    Towards accurate and unbiased imaging-based differentiation of Parkinson’s disease, progressive supranuclear palsy and corticobasal syndrome.

    DOI: http://doi.org/10.1093/braincomms/fcaa051
    Journal: Brain Commun
    E-pub date: 1 Aug 2020
    Authors: MM Correia, T Rittman, CL Barnes, IT Coyle-Gilchrist, B Ghosh, LE Hughes, JB Rowe

    Amplification, not spreading limits rate of tau aggregate accumulation in Alzheimer’s disease

    DOI: http://doi.org/10.1101/2020.11.16.384727
    Journal:
    E-pub date: 1 Aug 2020
    Authors: G Meisl, Y Zuo, K Allinson, T Rittman, S DeVos, J Sanchez, C Xu, K Duff, K Johnson, J Rowe, B Hyman, T Knowles, D Klenerman

    Microglial activation and tau burden predict cognitive decline in Alzheimer’s disease.

    DOI: http://doi.org/10.1093/brain/awaa088
    Journal: Brain
    E-pub date: 1 May 2020
    Authors: M Malpetti, RA Kievit, L Passamonti, PS Jones, KA Tsvetanov, T Rittman, E Mak, N Nicastro, WR Bevan-Jones, L Su, YT Hong, TD Fryer, FI Aigbirhio, JT O'Brien, JB Rowe

    Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia.

    DOI: http://doi.org/10.1136/jnnp-2019-321954
    Journal: J Neurol Neurosurg Psychiatry
    E-pub date: 1 Mar 2020
    Authors: C Heller, MS Foiani, K Moore, R Convery, M Bocchetta, M Neason, DM Cash, D Thomas, CV Greaves, IO Woollacott, R Shafei, JC Van Swieten, F Moreno, R Sanchez-Valle, B Borroni, R Laforce, M Masellis, MC Tartaglia, C Graff, D Galimberti, JB Rowe, E Finger, M Synofzik, R Vandenberghe, A de Mendonca, F Tagliavini, I Santana, S Ducharme, CR Butler, A Gerhard, J Levin, A Danek, G Frisoni, S Sorbi, M Otto, AJ Heslegrave, H Zetterberg, JD Rohrer, GENFI

    Falls in Progressive Supranuclear Palsy.

    DOI: http://doi.org/10.1002/mdc3.12879
    Journal: Mov Disord Clin Pract
    E-pub date: 1 Jan 2020
    Authors: FS Brown, JB Rowe, L Passamonti, T Rittman

    Asymmetrical atrophy of thalamic subnuclei in Alzheimer’s disease and amyloid-positive mild cognitive impairment is associated with key clinical features.

    DOI: http://doi.org/10.1016/j.dadm.2019.08.001
    Journal: Alzheimers Dement (Amst)
    E-pub date: 1 Dec 2019
    Authors: A Low, E Mak, M Malpetti, L Chouliaras, N Nicastro, L Su, N Holland, T Rittman, PV Rodríguez, L Passamonti, WR Bevan-Jones, PS Jones, JB Rowe, JT O'Brien

    Serum neurofilament light chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study.

    DOI: http://doi.org/10.1016/S1474-4422(19)30354-0
    Journal: Lancet Neurol
    E-pub date: 1 Dec 2019
    Authors: EL van der Ende, LH Meeter, JM Poos, JL Panman, LC Jiskoot, EGP Dopper, JM Papma, FJ de Jong, IMW Verberk, C Teunissen, D Rizopoulos, C Heller, RS Convery, KM Moore, M Bocchetta, M Neason, DM Cash, B Borroni, D Galimberti, R Sanchez-Valle, R Laforce, F Moreno, M Synofzik, C Graff, M Masellis, M Carmela Tartaglia, JB Rowe, R Vandenberghe, E Finger, F Tagliavini, A de Mendonça, I Santana, C Butler, S Ducharme, A Gerhard, A Danek, J Levin, M Otto, GB Frisoni, S Cappa, YAL Pijnenburg, JD Rohrer, JC van Swieten, Genetic Frontotemporal dementia Initiative (GENFI)

    Microglial activation and tau burden predict cognitive decline in Alzheimer’s Disease

    DOI: http://doi.org/10.1101/19011189
    Journal:
    E-pub date: 8 Nov 2019
    Authors: M Malpetti, R Kievit, L Passamonti, S Jones, K Tsvetanov, T Rittman, E Mak, N Nicastro, WR Bevan-Jones, L Su, Y Hong, T Fryer, F Aigbirhio, J O'Brien, J Rowe

    PET markers of tau and neuroinflammation are co-localized in progressive supranuclear palsy

    DOI: http://doi.org/10.1101/19010702
    Journal:
    E-pub date: 2 Nov 2019
    Authors: M Malpetti, L Passamonti, T Rittman, S Jones, P Vázquez Rodríguez, R Bevan-Jones, Y Hong, T Fryer, F Aigbirhio, J O’Brien, J Rowe

    Test Your Memory (TYM test): diagnostic evaluation of patients with non-Alzheimer dementias.

    DOI: http://doi.org/10.1007/s00415-019-09447-1
    Journal: J Neurol
    E-pub date: 1 Oct 2019
    Authors: J Brown, J Wiggins, CJ Lansdall, K Dawson, T Rittman, JB Rowe

    Atomoxetine and citalopram alter brain network organization in Parkinson’s disease.

    DOI: http://doi.org/10.1093/braincomms/fcz013
    Journal: Brain Commun
    E-pub date: 1 Aug 2019
    Authors: RJ Borchert, T Rittman, CL Rae, L Passamonti, SP Jones, D Vatansever, P Vázquez Rodríguez, Z Ye, C Nombela, LE Hughes, TW Robbins, JB Rowe

    White matter hyperintensities in progranulin-associated frontotemporal dementia: A longitudinal GENFI study.

    DOI: http://doi.org/10.1016/j.nicl.2019.102077
    Journal: Neuroimage Clin
    E-pub date: 1 Aug 2019
    Authors: CH Sudre, M Bocchetta, C Heller, R Convery, M Neason, KM Moore, DM Cash, DL Thomas, IOC Woollacott, M Foiani, A Heslegrave, R Shafei, C Greaves, J van Swieten, F Moreno, R Sanchez-Valle, B Borroni, R Laforce, M Masellis, MC Tartaglia, C Graff, D Galimberti, JB Rowe, E Finger, M Synofzik, R Vandenberghe, A de Mendonça, F Tagliavini, I Santana, S Ducharme, C Butler, A Gerhard, J Levin, A Danek, GB Frisoni, S Sorbi, M Otto, H Zetterberg, S Ourselin, MJ Cardoso, JD Rohrer, On behalf of, GENFI

    Neurological Assessment of Patients with Gliomas

    DOI: http://doi.org/10.1007/978-3-319-76747-5_3
    Journal:
    E-pub date: 1 Aug 2019
    Authors: T Ham, T Rittman

    O4‐03‐06: LONGITUDINAL ASSOCIATION BETWEEN APATHY AND COGNITIVE DECLINE IN PRE‐ AND POST‐SYMPTOMATIC GENETIC FRONTOTEMPORAL DEMENTIA

    DOI: http://doi.org/10.1016/j.jalz.2019.06.4757
    Journal: Alzheimer's & Dementia
    E-pub date: 1 Jul 2019
    Authors: M Malpetti, RA Kievit, PS Jones, T Rittman, KA Tsvetanov, JC van Swieten, B Borroni, D Galimberti, R Sanchez-Valle, R Laforce, F Moreno, M Synofzik, C Graff, M Masellis, C Tartaglia, R Vandenberghe, E Finger, F Tagliavini, A Mendonca, I Santana, CR Butler, S Ducharme, A Gerhard, A Danek, J Levin, M Otto, GB Frisoni, S Cappa, C Heller, RS Convery, KM Dick, JD Rohrer, JB Rowe

    Functional network resilience to pathology in presymptomatic genetic frontotemporal dementia.

    DOI: http://doi.org/10.1016/j.neurobiolaging.2018.12.009
    Journal: Neurobiol Aging
    E-pub date: 1 May 2019
    Authors: T Rittman, R Borchert, S Jones, J van Swieten, B Borroni, D Galimberti, M Masellis, MC Tartaglia, C Graff, F Tagliavini, GB Frisoni, R Laforce, E Finger, A Mendonça, S Sorbi, JD Rohrer, JB Rowe, Genetic Frontotemporal Dementia Initiative (GENFI)

    The inner fluctuations of the brain in presymptomatic Frontotemporal Dementia: The chronnectome fingerprint.

    DOI: http://doi.org/10.1016/j.neuroimage.2019.01.080
    Journal: Neuroimage
    E-pub date: 1 Apr 2019
    Authors: E Premi, VD Calhoun, M Diano, S Gazzina, M Cosseddu, A Alberici, S Archetti, D Paternicò, R Gasparotti, J van Swieten, D Galimberti, R Sanchez-Valle, R Laforce, F Moreno, M Synofzik, C Graff, M Masellis, MC Tartaglia, J Rowe, R Vandenberghe, E Finger, F Tagliavini, A de Mendonça, I Santana, C Butler, S Ducharme, A Gerhard, A Danek, J Levin, M Otto, G Frisoni, S Cappa, S Sorbi, A Padovani, JD Rohrer, B Borroni, Genetic FTD Initiative, GENFI

    In vivo coupling of tau pathology and cortical thinning in Alzheimer’s disease.

    DOI: http://doi.org/10.1016/j.dadm.2018.08.005
    Journal: Alzheimers Dement (Amst)
    E-pub date: 1 Aug 2018
    Authors: E Mak, RAI Bethlehem, R Romero-Garcia, S Cervenka, T Rittman, S Gabel, A Surendranathan, RW Bevan-Jones, L Passamonti, P Vázquez Rodríguez, L Su, R Arnold, GB Williams, YT Hong, TD Fryer, FI Aigbirhio, JB Rowe, JT O'Brien

    Reorganization of cortical oscillatory dynamics underlying disinhibition in frontotemporal dementia.

    DOI: http://doi.org/10.1093/brain/awy176
    Journal: Brain
    E-pub date: 1 Aug 2018
    Authors: LE Hughes, T Rittman, TW Robbins, JB Rowe

    Neurophysiological signatures of Alzheimer’s disease and frontotemporal lobar degeneration: pathology versus phenotype.

    DOI: http://doi.org/10.1093/brain/awy180
    Journal: Brain
    E-pub date: 1 Aug 2018
    Authors: S Sami, N Williams, LE Hughes, TE Cope, T Rittman, ITS Coyle-Gilchrist, RN Henson, JB Rowe

    Tau burden and the functional connectome in Alzheimer’s disease and progressive supranuclear palsy.

    DOI: http://doi.org/10.1093/brain/awx347
    Journal: Brain
    E-pub date: 1 Feb 2018
    Authors: TE Cope, T Rittman, RJ Borchert, PS Jones, D Vatansever, K Allinson, L Passamonti, P Vazquez Rodriguez, WR Bevan-Jones, JT O'Brien, JB Rowe

    Atomoxetine effects on attentional bias to drug-related cues in cocaine dependent individuals.

    DOI: http://doi.org/10.1007/s00213-017-4643-4
    Journal: Psychopharmacology (Berl)
    E-pub date: 31 Aug 2017
    Authors: L Passamonti, M Luijten, H Ziauddeen, ITS Coyle-Gilchrist, T Rittman, SAE Brain, R Regenthal, IHA Franken, BJ Sahakian, ET Bullmore, TW Robbins, KD Ersche

    Adolescence is Associated with Genomically Patterned Consolidation of the Hubs of the Human Brain Connectome

    DOI: http://doi.org/10.1016/j.biopsych.2017.02.390
    Journal: BIOLOGICAL PSYCHIATRY
    E-pub date: 1 Aug 2017
    Authors: K Whitaker, P Vertes, R Romero-Garcia, F Vasa, M Moutoussis, G Prabhub, N Weiskopf, M Callaghan, K Wagstyl, T Rittman, R Tait, C Ooi, J Suckling, B Inkster, P Fonagy, R Dolan, P Jones, I Goodyer, E Bullmore

    Intra-cortical myelination during adolescence: linking MRI networks with gene transcription profiles

    DOI: http://doi.org/10.1016/S0924-977X(17)31087-8
    Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
    E-pub date: 1 Aug 2017
    Authors: K Whitaker, P Vertes, R Romero-Garcia, F Vasa, M Moutoussis, G Prabhu, N Weiskopf, MF Callaghan, K Wagstyl, T Rittman, R Tait, C Ooi, J Suckling, B Inkster, P Fonagy, RJ Dolan, PB Jones, IM Goodyer, ET Bullmore

    Regional expression of the MAPT gene is associated with loss of hubs in brain networks and cognitive impairment in Parkinson disease and progressive supranuclear palsy.

    DOI: http://doi.org/10.1016/j.neurobiolaging.2016.09.001
    Journal: Neurobiol Aging
    E-pub date: 1 Dec 2016
    Authors: T Rittman, M Rubinov, PE Vértes, AX Patel, CE Ginestet, BCP Ghosh, RA Barker, MG Spillantini, ET Bullmore, JB Rowe

    Managing cognition in progressive supranuclear palsy.

    DOI: http://doi.org/10.2217/nmt-2016-0027
    Journal: Neurodegener Dis Manag
    E-pub date: 1 Dec 2016
    Authors: T Rittman, IT Coyle-Gilchrist, JB Rowe

    Gene transcription profiles associated with inter-modular hubs and connection distance in human functional magnetic resonance imaging networks.

    DOI: http://doi.org/10.1098/rstb.2015.0362
    Journal: Philos Trans R Soc Lond B Biol Sci
    E-pub date: 5 Oct 2016
    Authors: PE Vértes, T Rittman, KJ Whitaker, R Romero-Garcia, F Váša, MG Kitzbichler, K Wagstyl, P Fonagy, RJ Dolan, PB Jones, IM Goodyer, NSPN Consortium, ET Bullmore

    Atomoxetine restores the response inhibition network in Parkinson’s disease.

    DOI: http://doi.org/10.1093/brain/aww138
    Journal: Brain
    E-pub date: 31 Aug 2016
    Authors: CL Rae, C Nombela, PV Rodríguez, Z Ye, LE Hughes, PS Jones, T Ham, T Rittman, I Coyle-Gilchrist, R Regenthal, BJ Sahakian, RA Barker, TW Robbins, JB Rowe

    Adolescence is associated with genomically patterned consolidation of the hubs of the human brain connectome.

    DOI: http://doi.org/10.1073/pnas.1601745113
    Journal: Proc Natl Acad Sci U S A
    E-pub date: 9 Aug 2016
    Authors: KJ Whitaker, PE Vértes, R Romero-Garcia, F Váša, M Moutoussis, G Prabhu, N Weiskopf, MF Callaghan, K Wagstyl, T Rittman, R Tait, C Ooi, J Suckling, B Inkster, P Fonagy, RJ Dolan, PB Jones, IM Goodyer, NSPN Consortium, ET Bullmore

    Atomoxetine Enhances Connectivity of Prefrontal Networks in Parkinson’s Disease.

    DOI: http://doi.org/10.1038/npp.2016.18
    Journal: Neuropsychopharmacology
    E-pub date: 1 Jul 2016
    Authors: RJ Borchert, T Rittman, L Passamonti, Z Ye, S Sami, SP Jones, C Nombela, P Vázquez Rodríguez, D Vatansever, CL Rae, LE Hughes, TW Robbins, JB Rowe

    Atomoxetine Enhances Connectivity of Prefrontal Networks in Parkinson’s Disease.

    DOI: http://doi.org/10.1038/npp.2016.46
    Journal: Neuropsychopharmacology
    E-pub date: 1 Jul 2016
    Authors: RJ Borchert, T Rittman, L Passamonti, Z Ye, S Sami, SP Jones, C Nombela, PV Rodríguez, D Vatansever, CL Rae, LE Hughes, TW Robbins, JB Rowe

    The basal ganglia in cognitive disorders

    DOI: http://doi.org/10.1093/med/9780199655946.003.0007
    Journal:
    E-pub date: 1 Jun 2016
    Authors: J Rowe, T Rittman

    Predicting beneficial effects of atomoxetine and citalopram on response inhibition in Parkinson’s disease with clinical and neuroimaging measures.

    DOI: http://doi.org/10.1002/hbm.23087
    Journal: Hum Brain Mapp
    E-pub date: 1 Mar 2016
    Authors: Z Ye, CL Rae, C Nombela, T Ham, T Rittman, PS Jones, PV Rodríguez, I Coyle-Gilchrist, R Regenthal, E Altena, CR Housden, H Maxwell, BJ Sahakian, RA Barker, TW Robbins, JB Rowe

    Investigating ‘waiting impulsivity’ in cocaine addiction: are the effects of atomoxetine mediated by genotype?

    DOI: http://doi.org/10.1016/S0924-977X(15)30875-0
    Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
    E-pub date: 1 Aug 2015
    Authors: MI Pollard, H Ziauddeen, IT Coyle-Gilchrist, T Rittman, R Regenthal, S Abbott, BJ Sahakian, ET Bullmore, TW Robbins, KD Ersche

    Improving response inhibition systems in frontotemporal dementia with citalopram.

    DOI: http://doi.org/10.1093/brain/awv133
    Journal: Brain
    E-pub date: 1 Jul 2015
    Authors: LE Hughes, T Rittman, R Regenthal, TW Robbins, JB Rowe

    Connectivity biomarkers in neurodegenerative tauopathies

    DOI: http://doi.org/10.17863/CAM.13948
    Journal:
    E-pub date: 28 Apr 2015
    Authors: T Rittman

    Validation of the new consensus criteria for the diagnosis of corticobasal degeneration.

    DOI: http://doi.org/10.1136/jnnp-2013-307035
    Journal: J Neurol Neurosurg Psychiatry
    E-pub date: 31 Aug 2014
    Authors: SK Alexander, T Rittman, JH Xuereb, TH Bak, JR Hodges, JB Rowe

    Multiple modes of impulsivity in Parkinson’s disease.

    DOI: http://doi.org/10.1371/journal.pone.0085747
    Journal: PLoS One
    E-pub date: 1 Aug 2014
    Authors: C Nombela, T Rittman, TW Robbins, JB Rowe

    The medial frontal-prefrontal network for altered awareness and control of action in corticobasal syndrome.

    DOI: http://doi.org/10.1093/brain/awt302
    Journal: Brain
    E-pub date: 1 Jan 2014
    Authors: N Wolpe, JW Moore, CL Rae, T Rittman, E Altena, P Haggard, JB Rowe

    The Addenbrooke’s Cognitive Examination for the differential diagnosis and longitudinal assessment of patients with parkinsonian disorders.

    DOI: http://doi.org/10.1136/jnnp-2012-303618
    Journal: J Neurol Neurosurg Psychiatry
    E-pub date: 1 May 2013
    Authors: T Rittman, BC Ghosh, P McColgan, DP Breen, J Evans, CH Williams-Gray, RA Barker, JB Rowe

    Transcriptional data: a new gateway to drug repositioning?

    DOI: http://doi.org/10.1016/j.drudis.2012.07.014
    Journal: Drug Discov Today
    E-pub date: 1 Apr 2013
    Authors: F Iorio, T Rittman, H Ge, M Menden, J Saez-Rodriguez

    Is referral to the neuro-oncology MDT safe?

    DOI: http://doi.org/10.3109/02688697.2012.657267
    Journal: Br J Neurosurg
    E-pub date: 1 Jun 2012
    Authors: T Rittman, R Corns, A Kumar, R Bhangoo, K Ashkan

    THE UTILITY OF THE ADDENBROOKE’S COGNITIVE EXAMINATION-REVISED (ACE-R) IN PARKINSON’S DISEASE

    DOI: http://doi.org/10.1136/jnnp-2011-301993.3
    Journal: JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
    E-pub date: 1 Mar 2012
    Authors: P McColgan, J Evans, DP Breen, SL Mason, B Ghosh, T Rittman, J Rowe, P Nestor, RA Barker, CH Williams-Gray

    Nutritional factors associated with survival following enteral tube feeding in patients with motor neurone disease.

    DOI: http://doi.org/10.1111/j.1365-277X.2010.01057.x
    Journal: J Hum Nutr Diet
    E-pub date: 31 Aug 2010
    Authors: A Rio, C Ellis, C Shaw, E Willey, M-A Ampong, L Wijesekera, T Rittman, P Nigel Leigh, PS Sidhu, A Al-Chalabi

    Human papillomavirus infection in women who develop high-grade cervical intraepithelial neoplasia or cervical cancer: a case-control study in the UK.

    DOI: http://doi.org/10.1038/sj.bjc.6602538
    Journal: Br J Cancer
    E-pub date: 9 May 2005
    Authors: MJ Grainge, R Seth, C Coupland, L Guo, T Rittman, P Vryenhoef, J Johnson, D Jenkins, KR Neal