EMAIL tvl22@cam.ac.uk

College Clare Hall

Department

School

Clinical Medicine

Click to view ORCID profile

Research Theme Adaptive Brain Computations Neurons, Circuits and Networks

Research Focus

Keywords

Reinforcement Learning

Decision Making

Cognitive Neuroscience

Computational Psychiatry

Drug Addiction

Clinical Conditions

Addiction

Equipment & Techniques

Behavioural analysis

Computational modelling

Neuropsychological testing

Magnetic resonance imaging (MRI)

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Dr Tsen Vei Lim

(he/him/his)

University Position

Research Associate

Interests

I am a Society for the Study of Addiction (SSA) Academic Fellow at the Department of Psychiatry. My primary research interest lies at the intersection of computational psychiatry and substance use disorder. Specifically, I combine the use of experimental frameworks of instrumental learning and decision-making, as well as computational modelling techniques to disentangle the latent processes that underpin maladaptive behaviour in individuals with pathological substance use. Additionally, I am also interested in understanding the determinants of behavioural and cognitive flexibility, as well as habit formation within the general population.

Collaborators

Cambridge

Karen Ersche

Rudolf Cardinal

Trevor Robbins

Key Publications

Atomoxetine reduces decisional impulsivity in human cocaine addiction.

DOI: http://doi.org/10.1016/j.biopsych.2024.10.018
Journal: Biol Psychiatry
E-pub date: 29 Oct 2024
Authors: TV Lim, RN Cardinal, H Ziauddeen, R Regenthal, BJ Sahakian, TW Robbins, KD Ersche

Theory-driven computational models of drug addiction in humans: Fruitful or futile?

DOI: http://doi.org/10.1016/j.addicn.2023.100066
Journal: Addiction Neuroscience
E-pub date: 1 Mar 2023
Authors: TV Lim, KD Ersche

Impaired Learning From Negative Feedback in Stimulant Use Disorder: Dopaminergic Modulation.

DOI: http://doi.org/10.1093/ijnp/pyab041
Journal: Int J Neuropsychopharmacol
E-pub date: 12 Nov 2021
Authors: TV Lim, RN Cardinal, ET Bullmore, TW Robbins, KD Ersche

Reduced Glutamate Turnover in the Putamen Is Linked With Automatic Habits in Human Cocaine Addiction.

DOI: http://doi.org/10.1016/j.biopsych.2020.12.009
Journal: Biol Psychiatry
E-pub date: 15 May 2021
Authors: KD Ersche, TV Lim, AG Murley, C Rua, MM Vaghi, TL White, GB Williams, TW Robbins

Creature of Habit: A self-report measure of habitual routines and automatic tendencies in everyday life.

DOI: http://doi.org/10.1016/j.paid.2017.04.024
Journal: Pers Individ Dif
E-pub date: 1 Oct 2017
Authors: KD Ersche, T-V Lim, LHE Ward, TW Robbins, J Stochl

Dr Tsen Vei Lim

Interests

Collaborators

Key Publications

Atomoxetine reduces decisional impulsivity in human cocaine addiction.

Theory-driven computational models of drug addiction in humans: Fruitful or futile?

Impaired Learning From Negative Feedback in Stimulant Use Disorder: Dopaminergic Modulation.

Reduced Glutamate Turnover in the Putamen Is Linked With Automatic Habits in Human Cocaine Addiction.

Creature of Habit: A self-report measure of habitual routines and automatic tendencies in everyday life.

Publications

Reduced brain connectivity underlying value-based choices and outcomes in stimulant use disorder.

Differential profiles of cognitive and behavioral inflexibility in addictive disorders

Bridging minds and policies: supporting early career researchers in translating computational psychiatry research.

Goal-Directed and Habitual Control in Human Drug Addiction

The ‘Resilient Brain’: challenging key characteristics associated with the concept of resilience.

Impulsivity and compulsivity are differentially associated with automaticity and routine on the Creature of Habit Scale.

Impairments in reinforcement learning do not explain enhanced habit formation in cocaine use disorder.