Menu

EMAIL dkm13@cam.ac.uk
College Queens' College
Department
  • Medicine
    • Research Theme Beyond the Neuron Neurons, Circuits and Networks Lifelong Brain Development and Brain Ageing

    Other Interdiciplinary Incentives

  • 74

    • Research Focus

    Keywords

  • Traumatic Brain Injury
  • Consciousness
  • Disorders Of Consciousness
  • Ageing

    • Clinical Conditions

  • Traumatic brain injury

    • Equipment & Techniques

  • Positron Emission Tomography (PET)
  • Magnetic resonance imaging (MRI)

    • Back

    Professor David Menon CBE FMedSci

    (he/him/his)
    University Position
    Group Leader

    Interests

    DKM jointly leads the EU-funded €30 million CENTER-TBI Consortium (https://www.center-tbi.eu/), the International Initiative on TBI Research (InTBIR; https://intbir.incf.org/), and the multi-funder UK national Traumatic Brain Injury (TBI) Research Platform (TBI-REPORTER; https://tbi-reporter.uk/). He jointly led the Lancet Neurology Commissions on TBI in 2017 (https://www.thelancet.com/commissions/traumatic-brain-injury) and 2022 (https://www.thelancet.com/commissions/traumatic-brain-injury-progress), and was Executive Editor of the UK All Party Parliamentary Group Report on Acquired Brain Injury (2019: https://ukabif.org.uk/resource/resmgr/campaigns/appg-abi_report_time-for-cha.pdf).

    Associated News Items

    Key Publications

    Cognitive Motor Dissociation in Disorders of Consciousness.

    DOI: http://doi.org/10.1056/NEJMoa2400645
    Journal: N Engl J Med
    E-pub date: 15 Aug 2024
    Authors: YG Bodien, J Allanson, P Cardone, A Bonhomme, J Carmona, C Chatelle, S Chennu, M Conte, S Dehaene, P Finoia, G Heinonen, JE Hersh, E Kamau, PK Lawrence, VC Lupson, A Meydan, B Rohaut, WR Sanders, JD Sitt, A Soddu, M Valente, A Velazquez, HU Voss, A Vrosgou, J Claassen, BL Edlow, JJ Fins, O Gosseries, S Laureys, D Menon, L Naccache, AM Owen, J Pickard, EA Stamatakis, A Thibaut, JD Victor, JT Giacino, E Bagiella, ND Schiff

    Acute thalamic connectivity precedes chronic post-concussive symptoms in mild traumatic brain injury.

    DOI: http://doi.org/10.1093/brain/awad056
    Journal: Brain
    E-pub date: 1 Aug 2023
    Authors: RE Woodrow, S Winzeck, AI Luppi, IR Kelleher-Unger, LRB Spindler, JTL Wilson, VFJ Newcombe, JP Coles, CENTER-TBI MRI Substudy Participants and Investigators, DK Menon, EA Stamatakis

    Intrinsic brain dynamics in the Default Mode Network predict involuntary fluctuations of visual awareness

    DOI: http://doi.org/10.1038/s41467-022-34410-6
    Journal: Nat Commun
    E-pub date: 14 Nov 2022
    Authors: D Lyu, S Naik, DK Menon, EA Stamatakis

    Metabolic derangements are associated with impaired glucose delivery following traumatic brain injury.

    DOI: http://doi.org/10.1093/brain/awab255
    Journal: Brain
    E-pub date: 16 Dec 2021
    Authors: J Hermanides, YT Hong, M Trivedi, J Outtrim, F Aigbirhio, PJ Nestor, M Guilfoyle, S Winzeck, VFJ Newcombe, T Das, MM Correia, KLH Carpenter, PJA Hutchinson, AK Gupta, TD Fryer, JD Pickard, DK Menon, JP Coles

    Dopaminergic brainstem disconnection is common to pharmacological and pathological consciousness perturbation.

    DOI: http://doi.org/10.1073/pnas.2026289118
    Journal: Proc Natl Acad Sci U S A
    E-pub date: 27 Jul 2021
    Authors: LRB Spindler, AI Luppi, RM Adapa, MM Craig, P Coppola, ARD Peattie, AE Manktelow, P Finoia, BJ Sahakian, GB Williams, J Allanson, JD Pickard, DK Menon, EA Stamatakis

    Neuroanatomical Substrates and Symptoms Associated With Magnetic Resonance Imaging of Patients With Mild Traumatic Brain Injury.

    DOI: http://doi.org/10.1001/jamanetworkopen.2021.0994
    Journal: JAMA Netw Open
    E-pub date: 1 Mar 2021
    Authors: S Richter, S Winzeck, EN Kornaropoulos, T Das, T Vande Vyvere, J Verheyden, GB Williams, MM Correia, DK Menon, VFJ Newcombe, Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Magnetic Resonance Imaging (CENTER-TBI MRI) Substudy Participants and Investigators

    Structural optimality and neurogenetic expression mediate functional dynamics in the human brain.

    DOI: http://doi.org/10.1002/hbm.24942
    Journal: Hum Brain Mapp
    E-pub date: 1 Jun 2020
    Authors: I Pappas, MM Craig, DK Menon, EA Stamatakis

    Spatial and Temporal Pattern of Ischemia and Abnormal Vascular Function Following Traumatic Brain Injury.

    DOI: http://doi.org/10.1001/jamaneurol.2019.3854
    Journal: JAMA Neurol
    E-pub date: 1 Mar 2020
    Authors: Y Launey, TD Fryer, YT Hong, LA Steiner, J Nortje, TV Veenith, PJ Hutchinson, A Ercole, AK Gupta, FI Aigbirhio, JD Pickard, JP Coles, DK Menon

    Handling of Missing Outcome Data in Traumatic Brain Injury Research: A Systematic Review.

    DOI: http://doi.org/10.1089/neu.2018.6216
    Journal: J Neurotrauma
    E-pub date: 1 Oct 2019
    Authors: S Richter, S Stevenson, T Newman, L Wilson, DK Menon, AIR Maas, D Nieboer, H Lingsma, EW Steyerberg, VFJ Newcombe

    Default mode contributions to automated information processing.

    DOI: http://doi.org/10.1073/pnas.1710521114
    Journal: Proc Natl Acad Sci U S A
    E-pub date: 28 Nov 2017
    Authors: D Vatansever, DK Menon, EA Stamatakis

    Pathophysiologic Mechanisms of Cerebral Ischemia and Diffusion Hypoxia in Traumatic Brain Injury.

    DOI: http://doi.org/10.1001/jamaneurol.2016.0091
    Journal: JAMA Neurol
    E-pub date: 1 May 2016
    Authors: TV Veenith, EL Carter, T Geeraerts, J Grossac, VFJ Newcombe, J Outtrim, GS Gee, V Lupson, R Smith, FI Aigbirhio, TD Fryer, YT Hong, DK Menon, JP Coles

    Factoring the brain signatures of anesthesia concentration and level of arousal across individuals.

    DOI: http://doi.org/10.1016/j.nicl.2015.08.013
    Journal: Neuroimage Clin
    E-pub date: 1 Aug 2015
    Authors: P Barttfeld, TA Bekinschtein, A Salles, EA Stamatakis, R Adapa, DK Menon, M Sigman

    Diffusion limited oxygen delivery following head injury.

    DOI: http://doi.org/10.1097/01.ccm.0000127777.16609.08
    Journal: Crit Care Med
    E-pub date: 1 Jun 2004
    Authors: DK Menon, JP Coles, AK Gupta, TD Fryer, P Smielewski, DA Chatfield, F Aigbirhio, JN Skepper, PS Minhas, PJ Hutchinson, TA Carpenter, JC Clark, JD Pickard

    Incidence and mechanisms of cerebral ischemia in early clinical head injury.

    DOI: http://doi.org/10.1097/01.WCB.0000103022.98348.24
    Journal: J Cereb Blood Flow Metab
    E-pub date: 1 Feb 2004
    Authors: JP Coles, TD Fryer, P Smielewski, DA Chatfield, LA Steiner, AJ Johnston, SPMJ Downey, GB Williams, F Aigbirhio, PJ Hutchinson, K Rice, TA Carpenter, JC Clark, JD Pickard, DK Menon

    Publications

    Repeat traumatic brain injury exacerbates acute thalamic hyperconnectivity in humans

    DOI: http://doi.org/10.1093/braincomms/fcae223
    Journal: Brain Commun
    E-pub date: 1 Aug 2024
    Authors: RE Woodrow, K Amrein, N Andelic, L Andreassen, A Anke, P Azouvi, B Bellander, H Benali, A Buki, A Caccioppola, E Calappi, M Carbonara, G Citerio, H Clusmann, M Coburn, J Coles, M Correia, E Czeiter, V De Keyser, V Degos, B Depreitere, L Eikenes, E Ezer, K Foks, S Frisvold, D Galanaud, A Ghuysen, B Glocker, A Haberg, I Haitsma, E Helseth, PJ Hutchinson, E Kornaropoulos, N Kovács, A Kowark, S Laureys, D Ledoux, H Lingsma, AIR Maas, G Manley, DK Menon, T Menovsky, B Misset, V Muraleedharan, I Nakken, V Newcombe, W Nordhøy, J Nyirádi, F Ortolano, PM Parizel, V Perlbarg, P Persona, W Peul, JP Posti, L Puybasset, S Richter, C Roe, O Roise, R Rossaint, S Ross, D Rueckert, RD Singh, T Skandsen, A Sorinola, E Stamatakis, EW Steyerberg, N Stocchetti, R Takala, V Tamás, O Tenovuo, A Thibaut, Z Vámos, G Van der Steen, IA van Erp, W Van Hecke, T Vande Vyvere, J Verheyden, A Vik, V Volovici, LT Westlye, D Whitehouse, G Williams, S Winzeck, P Ylén, T Zoerle, DK Menon, EA Stamatakis

    A Synergistic Workspace for Human Consciousness Revealed by Integrated Information Decomposition

    DOI: http://doi.org/10.7554/eLife.88173
    Journal:
    E-pub date: 18 Jul 2024
    Authors: AI Luppi, PAM Mediano, FE Rosas, J Allanson, JD Pickard, RL Carhart-Harris, GB Williams, MM Craig, P Finoia, AM Owen, L Naci, DK Menon, D Bor, EA Stamatakis

    Systematic evaluation of fMRI data-processing pipelines for consistent functional connectomics

    DOI: http://doi.org/10.1038/s41467-024-48781-5
    Journal: Nat Commun
    E-pub date: 4 Jun 2024
    Authors: AI Luppi, HM Gellersen, Z-Q Liu, ARD Peattie, AE Manktelow, R Adapa, AM Owen, L Naci, DK Menon, SI Dimitriadis, EA Stamatakis

    A Synergistic Workspace for Human Consciousness Revealed by Integrated Information Decomposition

    DOI: http://doi.org/10.7554/elife.88173.3
    Journal:
    E-pub date: 15 May 2024
    Authors: AI Luppi, PAM Mediano, FE Rosas, J Allanson, JD Pickard, RL Carhart-Harris, GB Williams, MM Craig, P Finoia, AM Owen, L Naci, DK Menon, D Bor, EA Stamatakis

    Structural disconnectivity in postoperative delirium: A perioperative two-center cohort study in older patients.

    DOI: http://doi.org/10.1002/alz.13749
    Journal: Alzheimers Dement
    E-pub date: 1 Apr 2024
    Authors: M Fislage, S Winzeck, R Woodrow, F Lammers-Lietz, EA Stamatakis, MM Correia, J Preller, I Feinkohl, J Hendrikse, T Pischon, CD Spies, AJC Slooter, G Winterer, DK Menon, N Zacharias, BioCog Consortium

    Converging on consistent functional connectomics

    DOI: http://doi.org/10.1101/2023.06.23.546329
    Journal:
    E-pub date: 1 Aug 2023
    Authors: AI Luppi, HM Gellersen, Z-Q Liu, ARD Peattie, AE Manktelow, R Adapa, AM Owen, L Naci, DK Menon, SI Dimitriadis, EA Stamatakis

    A Synergistic Workspace for Human Consciousness Revealed by Integrated Information Decomposition

    DOI: http://doi.org/10.7554/elife.88173.1
    Journal:
    E-pub date: 25 Jul 2023
    Authors: AI Luppi, PAM Mediano, FE Rosas, J Allanson, JD Pickard, RL Carhart-Harris, GB Williams, MM Craig, P Finoia, AM Owen, L Naci, DK Menon, D Bor, EA Stamatakis

    Use of Support Vector Machines Approach via ComBat Harmonized Diffusion Tensor Imaging for the Diagnosis and Prognosis of Mild Traumatic Brain Injury: A CENTER-TBI Study.

    DOI: http://doi.org/10.1089/neu.2022.0365
    Journal: J Neurotrauma
    E-pub date: 1 Jul 2023
    Authors: M Siqueira Pinto, S Winzeck, EN Kornaropoulos, S Richter, R Paolella, MM Correia, B Glocker, G Williams, A Vik, JP Posti, A Haberg, J Stenberg, P-J Guns, AJ den Dekker, DK Menon, J Sijbers, P Van Dyck, VFJ Newcombe

    In vivo mapping of pharmacologically induced functional reorganization onto the human brain’s neurotransmitter landscape.

    DOI: http://doi.org/10.1126/sciadv.adf8332
    Journal: Sci Adv
    E-pub date: 16 Jun 2023
    Authors: AI Luppi, JY Hansen, R Adapa, RL Carhart-Harris, L Roseman, C Timmermann, D Golkowski, A Ranft, R Ilg, D Jordan, V Bonhomme, A Vanhaudenhuyse, A Demertzi, O Jaquet, MA Bahri, NLN Alnagger, P Cardone, ARD Peattie, AE Manktelow, DB de Araujo, SL Sensi, AM Owen, L Naci, DK Menon, B Misic, EA Stamatakis

    Depressive symptoms following traumatic brain injury are associated with resting-state functional connectivity.

    DOI: http://doi.org/10.1017/S0033291721004724
    Journal: Psychol Med
    E-pub date: 1 Apr 2023
    Authors: L Luo, C Langley, L Moreno-Lopez, K Kendrick, DK Menon, EA Stamatakis, BJ Sahakian

    Distributed harmonic patterns of structure-function dependence orchestrate human consciousness

    DOI: http://doi.org/10.1038/s42003-023-04474-1
    Journal: Commun Biol
    E-pub date: 28 Jan 2023
    Authors: AI Luppi, J Vohryzek, ML Kringelbach, PAM Mediano, MM Craig, R Adapa, RL Carhart-Harris, L Roseman, I Pappas, ARD Peattie, AE Manktelow, BJ Sahakian, P Finoia, GB Williams, J Allanson, JD Pickard, DK Menon, S Atasoy, EA Stamatakis

    The complexity of the stream of consciousness.

    DOI: http://doi.org/10.1038/s42003-022-04109-x
    Journal: Commun Biol
    E-pub date: 3 Nov 2022
    Authors: P Coppola, J Allanson, L Naci, R Adapa, P Finoia, GB Williams, JD Pickard, AM Owen, DK Menon, EA Stamatakis

    Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses.

    DOI: http://doi.org/10.1093/brain/awac321
    Journal: Brain
    E-pub date: 6 Sep 2022
    Authors: EJ Needham, AL Ren, RJ Digby, EJ Norton, S Ebrahimi, JG Outtrim, DA Chatfield, AE Manktelow, MM Leibowitz, VFJ Newcombe, R Doffinger, G Barcenas-Morales, C Fonseca, MJ Taussig, RM Burnstein, RJ Samanta, C Dunai, N Sithole, NJ Ashton, H Zetterberg, M Gisslén, A Edén, E Marklund, PJM Openshaw, J Dunning, MJ Griffiths, J Cavanagh, G Breen, SR Irani, A Elmer, N Kingston, C Summers, JR Bradley, LS Taams, BD Michael, ET Bullmore, KGC Smith, PA Lyons, AJ Coles, DK Menon, Cambridge NeuroCOVID Group, CITIID-NIHR COVID-19 BioResource Collaboration, Cambridge NIHR Clinical Research Facility

    Reduced emergent character of neural dynamics in patients with a disrupted connectome

    DOI: http://doi.org/10.1101/2022.06.16.496445
    Journal:
    E-pub date: 1 Aug 2022
    Authors: A Luppi, PAM Mediano, F Rosas, J Allanson, J Pickard, G Williams, M Craig, P Finoia, ARD Peattie, P Coppola, D Menon, D Bor, E Stamatakis

    Mapping Pharmacologically-induced Functional Reorganisation onto the Brain’s Neurotransmitter Landscape

    DOI: http://doi.org/10.1101/2022.07.12.499688
    Journal:
    E-pub date: 13 Jul 2022
    Authors: AI Luppi, JY Hansen, R Adapa, RL Carhart-Harris, L Roseman, C Timmermann, D Golkowski, A Ranft, R Ilg, D Jordan, V Bonhomme, A Vanhaudenhuyse, A Demertzi, O Jaquet, MA Bahri, NLN Alnagger, P Cardone, ARD Peattie, AE Manktelow, DB de Araujo, SL Sensi, AM Owen, L Naci, DK Menon, B Misic, EA Stamatakis

    Network dynamics scale with levels of awareness.

    DOI: http://doi.org/10.1016/j.neuroimage.2022.119128
    Journal: Neuroimage
    E-pub date: 1 Jul 2022
    Authors: P Coppola, LRB Spindler, AI Luppi, R Adapa, L Naci, J Allanson, P Finoia, GB Williams, JD Pickard, AM Owen, DK Menon, EA Stamatakis

    A synergistic core for human brain evolution and cognition.

    DOI: http://doi.org/10.1038/s41593-022-01070-0
    Journal: Nat Neurosci
    E-pub date: 1 Jun 2022
    Authors: AI Luppi, PAM Mediano, FE Rosas, N Holland, TD Fryer, JT O'Brien, JB Rowe, DK Menon, D Bor, EA Stamatakis

    Whole-brain modelling identifies distinct but convergent paths to unconsciousness in anaesthesia and disorders of consciousness.

    DOI: http://doi.org/10.1038/s42003-022-03330-y
    Journal: Commun Biol
    E-pub date: 20 Apr 2022
    Authors: AI Luppi, PAM Mediano, FE Rosas, J Allanson, JD Pickard, GB Williams, MM Craig, P Finoia, ARD Peattie, P Coppola, AM Owen, L Naci, DK Menon, D Bor, EA Stamatakis

    Measuring cerebral perfusion with [11C]-PiB R1 in Down syndrome: associations with amyloid burden and longitudinal cognitive decline.

    DOI: http://doi.org/10.1093/braincomms/fcaa198
    Journal: Brain Commun
    E-pub date: 1 Aug 2021
    Authors: E Mak, M Grigorova, J Beresford-Webb, M Malpetti, M Walpert, S Brown, E Jones, I Clare, YT Hong, TD Fryer, JP Coles, FI Aigbirhio, DK Menon, PJ Nestor, AJ Holland, SH Zaman

    Paths to Oblivion: Common Neural Mechanisms of Anaesthesia and Disorders of Consciousness

    DOI: http://doi.org/10.1101/2021.02.14.431140
    Journal:
    E-pub date: 1 Aug 2021
    Authors: A Luppi, PAM Mediano, F Rosas, J Allanson, J Pickard, G Williams, M Craig, P Finoia, ARD Peattie, P Coppola, A Owen, L Naci, D Menon, D Bor, E Stamatakis

    Searching for Consistent Brain Network Topologies Across the Garden of (Shortest) Forking Paths

    DOI: http://doi.org/10.1101/2021.07.13.452257
    Journal:
    E-pub date: 1 Aug 2021
    Authors: A Luppi, H Gellersen, A Peattie, A Manktelow, D Menon, S Dimitriadis, E Stamatakis

    Perturbation or Function? Intrinsic brain dynamics in the Default Mode Network predict involuntary fluctuations of visual awareness

    DOI: http://doi.org/10.21203/rs.3.rs-646785/v1
    Journal:
    E-pub date: 1 Aug 2021
    Authors: D Lu, E Stamatakis, S Naik, D Menon

    Network dynamics scale with levels of awareness

    DOI: http://doi.org/10.1101/2021.04.12.439452
    Journal:
    E-pub date: 1 Aug 2021
    Authors: P Coppola, LRB Spindler, A Luppi, R Adapa, L Naci, J Allanson, P Finoia, G Williams, J Pickard, A Owen, D Menon, E Stamatakis

    The Inert Brain: Explaining Neural Inertia as Post-anaesthetic Sleep Inertia.

    DOI: http://doi.org/10.3389/fnins.2021.643871
    Journal: Front Neurosci
    E-pub date: 1 Aug 2021
    Authors: AI Luppi, LRB Spindler, DK Menon, EA Stamatakis

    Brain network integration dynamics are associated with loss and recovery of consciousness induced by sevoflurane.

    DOI: http://doi.org/10.1002/hbm.25405
    Journal: Hum Brain Mapp
    E-pub date: 15 Jun 2021
    Authors: AI Luppi, D Golkowski, A Ranft, R Ilg, D Jordan, DK Menon, EA Stamatakis

    Outcome Prediction after Moderate and Severe Traumatic Brain Injury: External Validation of Two Established Prognostic Models in 1742 European Patients.

    DOI: http://doi.org/10.1089/neu.2020.7300
    Journal: J Neurotrauma
    E-pub date: 15 May 2021
    Authors: SA Dijkland, IRAR Helmrich, D Nieboer, M van der Jagt, DWJ Dippel, DK Menon, N Stocchetti, AIR Maas, HF Lingsma, EW Steyerberg, CENTER-TBI Participants and Investigators

    Propofol sedation-induced alterations in brain connectivity reflect parvalbumin interneurone distribution in human cerebral cortex.

    DOI: http://doi.org/10.1016/j.bja.2020.11.035
    Journal: Br J Anaesth
    E-pub date: 1 Apr 2021
    Authors: MM Craig, B Misic, I Pappas, RM Adapa, DK Menon, EA Stamatakis

    LSD alters dynamic integration and segregation in the human brain.

    DOI: http://doi.org/10.1016/j.neuroimage.2020.117653
    Journal: Neuroimage
    E-pub date: 15 Feb 2021
    Authors: AI Luppi, RL Carhart-Harris, L Roseman, I Pappas, DK Menon, EA Stamatakis

    Understanding the relationship between cognitive performance and function in daily life after traumatic brain injury.

    DOI: http://doi.org/10.1136/jnnp-2020-324492
    Journal: J Neurol Neurosurg Psychiatry
    E-pub date: 2 Dec 2020
    Authors: L Wilson, L Horton, K Kunzmann, BJ Sahakian, VF Newcombe, EA Stamatakis, N von Steinbuechel, K Cunitz, A Covic, A Maas, D Van Praag, D Menon, CENTER-TBI participants and investigators

    Diffusion structural network metrics as a predictor for Alzheimer’s disease diagnosis in Down syndrome using support vector machine classification

    DOI: http://doi.org/10.1002/alz.040261
    Journal: Alzheimer's & Dementia
    E-pub date: 1 Dec 2020
    Authors: SSG Brown, E Mak, M Grigorova, J Beresford‐Webb, MJ Walpert, E Jones, YT Hong, TD Fryer, JP Coles, FI Aigbirhio, BL Handen, BT Christian, WE Klunk, DK Menon, PJ Nestor, AJ Holland, S Zaman

    Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study.

    DOI: http://doi.org/10.1016/S2215-0366(20)30287-X
    Journal: Lancet Psychiatry
    E-pub date: 1 Oct 2020
    Authors: A Varatharaj, N Thomas, MA Ellul, NWS Davies, TA Pollak, EL Tenorio, M Sultan, A Easton, G Breen, M Zandi, JP Coles, H Manji, R Al-Shahi Salman, DK Menon, TR Nicholson, LA Benjamin, A Carson, C Smith, MR Turner, T Solomon, R Kneen, SL Pett, I Galea, RH Thomas, BD Michael, CoroNerve Study Group

    A Synergistic Workspace for Human Consciousness Revealed by Integrated Information Decomposition

    DOI: http://doi.org/10.1101/2020.11.25.398081
    Journal:
    E-pub date: 1 Aug 2020
    Authors: A Luppi, PAM Mediano, F Rosas, J Allanson, J Pickard, R Carhart-Harris, G Williams, M Craig, P Finoia, A Owen, L Naci, D Menon, D Bor, E Stamatakis

    A synergistic core for human brain evolution and cognition

    DOI: http://doi.org/10.1101/2020.09.22.308981
    Journal:
    E-pub date: 1 Aug 2020
    Authors: A Luppi, PAM Mediano, F Rosas, N Holland, T Fryer, J O’Brien, J Rowe, D Menon, D Bor, E Stamatakis

    Distributed harmonic patterns of structure-function dependence orchestrate human consciousness

    DOI: http://doi.org/10.1101/2020.08.10.244459
    Journal:
    E-pub date: 1 Aug 2020
    Authors: A Luppi, J Vohryzek, M Kringelbach, PAM Mediano, M Craig, R Adapa, R Carhart-Harris, L Roseman, I Pappas, ARD Peattie, A Manktelow, B Sahakian, P Finoia, G Williams, J Allanson, J Pickard, D Menon, S Atasoy, E Stamatakis

    Fractal dimension of cortical functional connectivity networks & severity of disorders of consciousness.

    DOI: http://doi.org/10.1371/journal.pone.0223812
    Journal: PLoS One
    E-pub date: 1 Aug 2020
    Authors: TF Varley, M Craig, R Adapa, P Finoia, G Williams, J Allanson, J Pickard, DK Menon, EA Stamatakis

    Neurological Implications of COVID-19 Infections.

    DOI: http://doi.org/10.1007/s12028-020-00978-4
    Journal: Neurocrit Care
    E-pub date: 1 Jun 2020
    Authors: EJ Needham, SH-Y Chou, AJ Coles, DK Menon

    Reorganisation of Brain Hubs across Altered States of Consciousness.

    DOI: http://doi.org/10.1038/s41598-020-60258-1
    Journal: Sci Rep
    E-pub date: 25 Feb 2020
    Authors: D Vatansever, M Schröter, RM Adapa, ET Bullmore, DK Menon, EA Stamatakis

    Consciousness & Brain Functional Complexity in Propofol Anaesthesia.

    DOI: http://doi.org/10.1038/s41598-020-57695-3
    Journal: Sci Rep
    E-pub date: 23 Jan 2020
    Authors: TF Varley, AI Luppi, I Pappas, L Naci, R Adapa, AM Owen, DK Menon, EA Stamatakis

    δ-Oscillation Correlates of Anesthesia-induced Unconsciousness in Large-scale Brain Networks of Human Infants.

    DOI: http://doi.org/10.1097/ALN.0000000000002977
    Journal: Anesthesiology
    E-pub date: 1 Dec 2019
    Authors: I Pappas, L Cornelissen, DK Menon, CB Berde, EA Stamatakis

    Consciousness-specific dynamic interactions of brain integration and functional diversity.

    DOI: http://doi.org/10.1038/s41467-019-12658-9
    Journal: Nat Commun
    E-pub date: 10 Oct 2019
    Authors: AI Luppi, MM Craig, I Pappas, P Finoia, GB Williams, J Allanson, JD Pickard, AM Owen, L Naci, DK Menon, EA Stamatakis

    Delineating the topography of amyloid-associated cortical atrophy in Down syndrome.

    DOI: http://doi.org/10.1016/j.neurobiolaging.2019.02.018
    Journal: Neurobiol Aging
    E-pub date: 31 Aug 2019
    Authors: E Mak, C Padilla, T Annus, LR Wilson, YT Hong, TD Fryer, JP Coles, FI Aigbirhio, DK Menon, PJ Nestor, SH Zaman, AJ Holland

    Fractal Dimension of Cortical Functional Connectivity Networks Predicts Severity in Disorders of Consciousness

    DOI: http://doi.org/10.1101/789636
    Journal:
    E-pub date: 1 Aug 2019
    Authors: TF Varley, M Craig, R Adapa, P Finoia, G Williams, J Alanson, J Pickard, DK Menon, EA Stamatakis

    Brain network disintegration during sedation is mediated by the complexity of sparsely connected regions.

    DOI: http://doi.org/10.1016/j.neuroimage.2018.10.078
    Journal: Neuroimage
    E-pub date: 1 Feb 2019
    Authors: I Pappas, RM Adapa, DK Menon, EA Stamatakis

    Methylphenidate-mediated motor control network enhancement in patients with traumatic brain injury.

    DOI: http://doi.org/10.1080/02699052.2018.1469166
    Journal: Brain Inj
    E-pub date: 1 Aug 2018
    Authors: CL Dorer, AE Manktelow, J Allanson, BJ Sahakian, JD Pickard, A Bateman, DK Menon, EA Stamatakis

    Personalised treatments for traumatic brain injury: cognitive, emotional and motivational targets.

    DOI: http://doi.org/10.1017/S0033291718000892
    Journal: Psychol Med
    E-pub date: 1 Jul 2018
    Authors: G Savulich, DK Menon, EA Stamatakis, JD Pickard, BJ Sahakian

    Default Mode Network Engagement Beyond Self-Referential Internal Mentation.

    DOI: http://doi.org/10.1089/brain.2017.0489
    Journal: Brain Connect
    E-pub date: 1 May 2018
    Authors: D Vatansever, A Manktelow, BJ Sahakian, DK Menon, EA Stamatakis

    Spectral Diversity in Default Mode Network Connectivity Reflects Behavioral State.

    DOI: http://doi.org/10.1162/jocn_a_01213
    Journal: J Cogn Neurosci
    E-pub date: 1 Apr 2018
    Authors: MM Craig, AE Manktelow, BJ Sahakian, DK Menon, EA Stamatakis

    Functional SNP allele discovery (fSNPd): an approach to find highly penetrant, environmental-triggered genotypes underlying complex human phenotypes.

    DOI: http://doi.org/10.1186/s12864-017-4325-y
    Journal: BMC Genomics
    E-pub date: 4 Dec 2017
    Authors: K Stouffer, M Nahorski, P Moreno, N Sarveswaran, D Menon, M Lee, C Geoffrey Woods

    Brain-predicted age in Down syndrome is associated with beta amyloid deposition and cognitive decline.

    DOI: http://doi.org/10.1016/j.neurobiolaging.2017.04.006
    Journal: Neurobiol Aging
    E-pub date: 31 Aug 2017
    Authors: JH Cole, T Annus, LR Wilson, R Remtulla, YT Hong, TD Fryer, J Acosta-Cabronero, A Cardenas-Blanco, R Smith, DK Menon, SH Zaman, PJ Nestor, AJ Holland

    Neural correlates of visual memory in patients with diffuse axonal injury.

    DOI: http://doi.org/10.1080/02699052.2017.1341998
    Journal: Brain Inj
    E-pub date: 1 Aug 2017
    Authors: J Lauer, L Moreno-López, A Manktelow, EL Carroll, JG Outtrim, JP Coles, VF Newcombe, BJ Sahakian, DK Menon, EA Stamatakis

    Working Memory after Traumatic Brain Injury: The Neural Basis of Improved Performance with Methylphenidate.

    DOI: http://doi.org/10.3389/fnbeh.2017.00058
    Journal: Front Behav Neurosci
    E-pub date: 1 Aug 2017
    Authors: AE Manktelow, DK Menon, BJ Sahakian, EA Stamatakis

    The Down syndrome brain in the presence and absence of fibrillar β-amyloidosis.

    DOI: http://doi.org/10.1016/j.neurobiolaging.2017.01.009
    Journal: Neurobiol Aging
    E-pub date: 1 May 2017
    Authors: T Annus, LR Wilson, J Acosta-Cabronero, A Cardenas-Blanco, YT Hong, TD Fryer, JP Coles, DK Menon, SH Zaman, AJ Holland, PJ Nestor

    Anything goes? Regulation of the neural processes underlying response inhibition in TBI patients.

    DOI: http://doi.org/10.1016/j.euroneuro.2016.12.002
    Journal: Eur Neuropsychopharmacol
    E-pub date: 1 Feb 2017
    Authors: L Moreno-López, AE Manktelow, BJ Sahakian, DK Menon, EA Stamatakis

    Angular default mode network connectivity across working memory load.

    DOI: http://doi.org/10.1002/hbm.23341
    Journal: Hum Brain Mapp
    E-pub date: 1 Jan 2017
    Authors: D Vatansever, AE Manktelow, BJ Sahakian, DK Menon, EA Stamatakis

    Depression following traumatic brain injury: A functional connectivity perspective.

    DOI: http://doi.org/10.1080/02699052.2016.1186839
    Journal: Brain Inj
    E-pub date: 1 Aug 2016
    Authors: L Moreno-López, BJ Sahakian, A Manktelow, DK Menon, EA Stamatakis

    The see-saw brain: recovering consciousness after brain injury.

    DOI: http://doi.org/10.1016/S1474-4422(16)30027-8
    Journal: Lancet Neurol
    E-pub date: 1 Jul 2016
    Authors: S Chennu, EA Stamatakis, DK Menon

    The pattern of amyloid accumulation in the brains of adults with Down syndrome.

    DOI: http://doi.org/10.1016/j.jalz.2015.07.490
    Journal: Alzheimers Dement
    E-pub date: 1 May 2016
    Authors: T Annus, LR Wilson, YT Hong, J Acosta-Cabronero, TD Fryer, A Cardenas-Blanco, R Smith, I Boros, JP Coles, FI Aigbirhio, DK Menon, SH Zaman, PJ Nestor, AJ Holland

    Cognitive Flexibility: A Default Network and Basal Ganglia Connectivity Perspective.

    DOI: http://doi.org/10.1089/brain.2015.0388
    Journal: Brain Connect
    E-pub date: 1 Apr 2016
    Authors: D Vatansever, AE Manktelow, BJ Sahakian, DK Menon, EA Stamatakis

    Dynamic Changes in White Matter Abnormalities Correlate With Late Improvement and Deterioration Following TBI: A Diffusion Tensor Imaging Study.

    DOI: http://doi.org/10.1177/1545968315584004
    Journal: Neurorehabil Neural Repair
    E-pub date: 1 Jan 2016
    Authors: VFJ Newcombe, MM Correia, C Ledig, MG Abate, JG Outtrim, D Chatfield, T Geeraerts, AE Manktelow, E Garyfallidis, JD Pickard, BJ Sahakian, PJA Hutchinson, D Rueckert, JP Coles, GB Williams, DK Menon

    Default Mode Dynamics for Global Functional Integration.

    DOI: http://doi.org/10.1523/JNEUROSCI.2135-15.2015
    Journal: J Neurosci
    E-pub date: 18 Nov 2015
    Authors: D Vatansever, DK Menon, AE Manktelow, BJ Sahakian, EA Stamatakis

    Default mode network connectivity during task execution.

    DOI: http://doi.org/10.1016/j.neuroimage.2015.07.053
    Journal: Neuroimage
    E-pub date: 15 Nov 2015
    Authors: D Vatansever, DK Menon, AE Manktelow, BJ Sahakian, EA Stamatakis

    Early-Phase 11C-PiB PET in Amyloid Angiopathy-Related Symptomatic Cerebral Hemorrhage: Potential Diagnostic Value?

    DOI: http://doi.org/10.1371/journal.pone.0139926
    Journal: PLoS One
    E-pub date: 1 Aug 2015
    Authors: K Farid, YT Hong, FI Aigbirhio, TD Fryer, DK Menon, EA Warburton, J-C Baron

    White matter perivascular spaces on magnetic resonance imaging: marker of cerebrovascular amyloid burden?

    DOI: http://doi.org/10.1161/STROKEAHA.115.009090
    Journal: Stroke
    E-pub date: 1 Jun 2015
    Authors: A Charidimou, YT Hong, HR Jäger, Z Fox, FI Aigbirhio, TD Fryer, DK Menon, EA Warburton, DJ Werring, J-C Baron

    Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI): a prospective longitudinal observational study.

    DOI: http://doi.org/10.1227/NEU.0000000000000575
    Journal: Neurosurgery
    E-pub date: 1 Jan 2015
    Authors: AIR Maas, DK Menon, EW Steyerberg, G Citerio, F Lecky, GT Manley, S Hill, V Legrand, A Sorgner, CENTER-TBI Participants and Investigators

    Amyloid imaging with carbon 11-labeled Pittsburgh compound B for traumatic brain injury.

    DOI: http://doi.org/10.1001/jamaneurol.2013.4847
    Journal: JAMA Neurol
    E-pub date: 1 Jan 2014
    Authors: YT Hong, T Veenith, D Dewar, JG Outtrim, V Mani, C Williams, S Pimlott, PJA Hutchinson, A Tavares, R Canales, CA Mathis, WE Klunk, FI Aigbirhio, JP Coles, J-C Baron, JD Pickard, TD Fryer, W Stewart, DK Menon

    Neural correlates of successful semantic processing during propofol sedation.

    DOI: http://doi.org/10.1002/hbm.22375
    Journal: Human Brain Mapping
    E-pub date: 1 Jan 2014
    Authors: RM Adapa, MH Davis, EA Stamatakis, AR Absalom, DK Menon

    Diagnostic utility of amyloid PET in cerebral amyloid angiopathy-related symptomatic intracerebral hemorrhage.

    DOI: http://doi.org/10.1038/jcbfm.2014.43
    Journal: Journal of Cerebral Blood Flow and Metabolism
    E-pub date: 1 Jan 2014
    Authors: J-C Baron, K Farid, E Dolan, G Turc, ST Marrapu, E O'Brien, FI Aigbirhio, TD Fryer, DK Menon, EA Warburton, YT Hong

    Microstructural basis of contusion expansion in traumatic brain injury: insights from diffusion tensor imaging.

    DOI: http://doi.org/10.1038/jcbfm.2013.11
    Journal: J Cereb Blood Flow Metab
    E-pub date: 1 Jun 2013
    Authors: VFJ Newcombe, GB Williams, JG Outtrim, D Chatfield, M Gulia Abate, T Geeraerts, A Manktelow, H Room, L Mariappen, PJ Hutchinson, JP Coles, DK Menon

    Critical thresholds for cerebrovascular reactivity after traumatic brain injury.

    DOI: http://doi.org/10.1007/s12028-011-9630-8
    Journal: Neurocrit Care
    E-pub date: 1 Apr 2012
    Authors: E Sorrentino, J Diedler, M Kasprowicz, KP Budohoski, C Haubrich, P Smielewski, JG Outtrim, A Manktelow, PJ Hutchinson, JD Pickard, DK Menon, M Czosnyka

    A microPET study of the regional distribution of [11C]-PK11195 binding following temporary focal cerebral ischemia in the rat. Correlation with post mortem mapping of microglia activation.

    DOI: http://doi.org/10.1016/j.neuroimage.2011.10.060
    Journal: Neuroimage
    E-pub date: 1 Feb 2012
    Authors: JL Hughes, PS Jones, JS Beech, D Wang, DK Menon, FI Aigbirhio, TD Fryer, JC Baron

    IC‐P‐156: Imaging brain fibrillar β‐amyloid in adults with Down syndrome (DS) using [11C] PiB‐PET: acceptability, feasibility and preliminary results

    DOI: http://doi.org/10.1016/j.jalz.2011.05.170
    Journal: Alzheimer's & Dementia
    E-pub date: 1 Jul 2011
    Authors: Jean‐Claude Baron, J Landt, JC D'Abrera, A Holland, F Aigbirhio, T Fryer, R Canales, Y Hong, D Menon, J Baron, S Zaman

    Using positron emission tomography and Carbon 11-labeled Pittsburgh Compound B to image Brain Fibrillar β-amyloid in adults with down syndrome: safety, acceptability, and feasibility.

    DOI: http://doi.org/10.1001/archneurol.2011.36
    Journal: Arch Neurol
    E-pub date: 1 Jul 2011
    Authors: J Landt, JC D'Abrera, AJ Holland, FI Aigbirhio, TD Fryer, R Canales, YT Hong, DK Menon, J-C Baron, SH Zaman

    Validation of reference tissue modelling for [11C]flumazenil positron emission tomography following head injury.

    DOI: http://doi.org/10.1007/s12149-011-0480-4
    Journal: Annals of Nuclear Medicine
    E-pub date: 1 Jul 2011
    Authors: T Geeraerts, JP Coles, FI Aigbirhio, JD Pickard, DK Menon, TD Fryer, YT Hong

    Traumatic brain injury alters the functional brain network mediating working memory.

    DOI: http://doi.org/10.3109/02699052.2011.608210
    Journal: Brain Injury
    E-pub date: 1 Jan 2011
    Authors: M Kasahara, DK Menon, CH Salmond, JG Outtrim, JVT Tavares, TA Carpenter, JD Pickard, BJ Sahakian, EA Stamatakis

    Changes in resting neural connectivity during propofol sedation.

    DOI: http://doi.org/10.1371/journal.pone.0014224
    Journal: PLoS One
    E-pub date: 2 Dec 2010
    Authors: EA Stamatakis, RM Adapa, AR Absalom, DK Menon

    Altered functional connectivity in the motor network after traumatic brain injury.

    DOI: http://doi.org/10.1212/WNL.0b013e3181e7ca58
    Journal: Neurology
    E-pub date: 13 Jul 2010
    Authors: M Kasahara, DK Menon, CH Salmond, JG Outtrim, JV Taylor Tavares, TA Carpenter, JD Pickard, BJ Sahakian, EA Stamatakis

    A combined microdialysis and FDG-PET study of glucose metabolism in head injury.

    DOI: http://doi.org/10.1007/s00701-008-0169-1
    Journal: ACTA NEUROCHIR
    E-pub date: 1 Jan 2009
    Authors: PJ Hutchinson, MT O'Connell, A Seal, J Nortje, I Timofeev, PG Al-Rawi, JP Coles, TD Fryer, DK Menon, JD Pickard, KLH Carpenter

    Early derangements in oxygen and glucose metabolism following head injury: the ischemic penumbra and pathophysiological heterogeneity.

    DOI: http://doi.org/10.1007/s12028-008-9119-2
    Journal: Neurocrit Care
    E-pub date: 1 Aug 2008
    Authors: MG Abate, M Trivedi, TD Fryer, P Smielewski, DA Chatfield, GB Williams, F Aigbirhio, TA Carpenter, JD Pickard, DK Menon, JP Coles

    Effect of hyperoxia on regional oxygenation and metabolism after severe traumatic brain injury: preliminary findings.

    DOI: http://doi.org/10.1097/01.CCM.0000292014.60835.15
    Journal: Crit Care Med
    E-pub date: 1 Jan 2008
    Authors: J Nortje, JP Coles, I Timofeev, TD Fryer, FI Aigbirhio, P Smielewski, JG Outtrim, DA Chatfield, JD Pickard, PJ Hutchinson, AK Gupta, DK Menon

    Imaging of brain hypoxia in permanent and temporary middle cerebral artery occlusion in the rat using 18F-fluoromisonidazole and positron emission tomography: a pilot study.

    DOI: http://doi.org/10.1038/sj.jcbfm.9600405
    Journal: J Cereb Blood Flow Metab
    E-pub date: 1 Apr 2007
    Authors: M Takasawa, JS Beech, TD Fryer, YT Hong, JL Hughes, K Igase, PS Jones, R Smith, FI Aigbirhio, DK Menon, JC Clark, J-C Baron

    Hyperventilation following head injury: effect on ischemic burden and cerebral oxidative metabolism.

    DOI: http://doi.org/10.1097/01.CCM.0000254066.37187.88
    Journal: Crit Care Med
    E-pub date: 1 Feb 2007
    Authors: JP Coles, TD Fryer, MR Coleman, P Smielewski, AK Gupta, PS Minhas, F Aigbirhio, DA Chatfield, GB Williams, S Boniface, TA Carpenter, JC Clark, JD Pickard, DK Menon

    Intrinsic activated microglia map to the peri-infarct zone in the subacute phase of ischemic stroke.

    DOI: http://doi.org/10.1161/01.STR.0000226980.95389.0b
    Journal: Stroke
    E-pub date: 1 Jul 2006
    Authors: CJS Price, D Wang, DK Menon, JV Guadagno, M Cleij, T Fryer, F Aigbirhio, J-C Baron, EA Warburton

    Intersubject variability and reproducibility of 15O PET studies.

    DOI: http://doi.org/10.1038/sj.jcbfm.9600179
    Journal: J Cereb Blood Flow Metab
    E-pub date: 1 Jan 2006
    Authors: JP Coles, TD Fryer, PG Bradley, J Nortje, P Smielewski, K Rice, JC Clark, JD Pickard, DK Menon

    Coexisting low cerebral blood flow and volume in head injury is due to microvascular ischaemia, not hypometabolism

    DOI: http://doi.org/10.1097/00003643-200509001-00072
    Journal: European Journal of Anaesthesiology
    E-pub date: 1 Sep 2005
    Authors: JP Coles, DK Menon, TD Fryer, DA Chatfield, AK Gupta, LA Steiner, AJ Johnston, J Nortje, PJA Hutchinson, FI Aigbirhio, JC Clark, JD Pickard

    Sources of variability in oxygen-15 PET studies in acute brain injury – impact on sample size estimation

    DOI: http://doi.org/10.1038/sj.jcbfm.9591524.0675
    Journal: Journal of Cerebral Blood Flow & Metabolism
    E-pub date: 31 Aug 2005
    Authors: JP Coles, TD Fryer, PG Bradley, J Nortje, P Smielewski, K Rice, JC Clark, JD Pickard, DK Menon

    15O-PET shows that cerebral blood volume is increased in head injury, but may still not be the dominant cause of intracranial hypertension

    DOI: http://doi.org/10.1038/sj.jcbfm.9591524.0317
    Journal: Journal of Cerebral Blood Flow & Metabolism
    E-pub date: 31 Aug 2005
    Authors: DK Menon, JP Coles, TD Fryer, DA Chatfield, LA Steiner, AJ Johnston, FI Aigbirhio, JC Clark, JD Pickard

    Physiological thresholds for irreversible tissue damage in contusional regions following traumatic brain injury.

    DOI: http://doi.org/10.1093/brain/awh536
    Journal: Brain
    E-pub date: 31 Aug 2005
    Authors: AS Cunningham, R Salvador, JP Coles, DA Chatfield, PG Bradley, AJ Johnston, LA Steiner, TD Fryer, FI Aigbirhio, P Smielewski, GB Williams, TA Carpenter, JH Gillard, JD Pickard, DK Menon

    Neurometabolic coupling in the vegetative and minimally conscious states: preliminary findings.

    DOI: http://doi.org/10.1136/jnnp.2004.045930
    Journal: J Neurol Neurosurg Psychiatry
    E-pub date: 1 Mar 2005
    Authors: MR Coleman, DK Menon, TD Fryer, JD Pickard

    Effect of cerebral perfusion pressure augmentation on regional oxygenation and metabolism after head injury.

    DOI: http://doi.org/10.1097/01.ccm.0000149837.09225.bd
    Journal: Crit Care Med
    E-pub date: 1 Jan 2005
    Authors: AJ Johnston, LA Steiner, JP Coles, DA Chatfield, TD Fryer, P Smielewski, PJ Hutchinson, MT O'Connell, PG Al-Rawi, FI Aigbirihio, JC Clark, JD Pickard, AK Gupta, DK Menon

    Glucose metabolism in traumatic brain injury: a combined microdialysis and [18F]-2-fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET) study.

    DOI: http://doi.org/10.1007/3-211-32318-X_35
    Journal: Acta Neurochirurgica Supplementum
    E-pub date: 1 Jan 2005
    Authors: MT O'Connell, A Seal, J Nortje, PG Al-Rawi, JP Coles, TD Fryer, DK Menon, JD Pickard, PJ Hutchinson

    Imaging of cerebral blood flow and metabolism in brain injury in the ICU.

    DOI: http://doi.org/10.1007/3-211-32318-X_94
    Journal: Acta Neurochirurgica Supplementum
    E-pub date: 1 Jan 2005
    Authors: JD Pickard, PJ Hutchinson, JP Coles, LA Steiner, AJ Johnston, TD Fryer, MR Coleman, P Smielewski, DA Chatfield, F Aigbirhio, GB Williams, K Rice, JC Clark, CH Salmond, BJ Sahakian, PG Bradley, TA Carpenter, R Salvador, A Pena, JH Gillard, AS Cunningham, S Piechnik, M Czosnyka, DK Menon

    Does induced hypertension reduce cerebral ischaemia within the traumatized human brain?

    DOI: http://doi.org/10.1093/brain/awh268
    Journal: Brain
    E-pub date: 1 Nov 2004
    Authors: JP Coles, LA Steiner, AJ Johnston, TD Fryer, MR Coleman, P Smieleweski, DA Chatfield, F Aigbirhio, GB Williams, S Boniface, K Rice, JC Clark, JD Pickard, DK Menon

    Cerebral neutrophil recruitment, histology, and outcome in acute ischemic stroke: an imaging-based study.

    DOI: http://doi.org/10.1161/01.STR.0000130592.71028.92
    Journal: Stroke
    E-pub date: 1 Jul 2004
    Authors: CJS Price, DK Menon, AM Peters, JR Ballinger, RW Barber, KK Balan, A Lynch, JH Xuereb, T Fryer, JV Guadagno, EA Warburton

    Defining ischemic burden after traumatic brain injury using 15O PET imaging of cerebral physiology.

    DOI: http://doi.org/10.1097/01.WCB.0000100045.07481.DE
    Journal: J Cereb Blood Flow Metab
    E-pub date: 1 Feb 2004
    Authors: JP Coles, TD Fryer, P Smielewski, K Rice, JC Clark, JD Pickard, DK Menon

    Responses of posttraumatic pericontusional cerebral blood flow and blood volume to an increase in cerebral perfusion pressure.

    DOI: http://doi.org/10.1097/01.WCB.0000090861.67713.10
    Journal: J Cereb Blood Flow Metab
    E-pub date: 1 Nov 2003
    Authors: LA Steiner, JP Coles, AJ Johnston, M Czosnyka, TD Fryer, P Smielewski, DA Chatfield, R Salvador, FI Aigbirhio, JC Clark, DK Menon, JD Pickard

    Evaluation of an MRI-based protocol for cell implantation in four patients with Huntington’s disease.

    DOI: http://doi.org/10.3727/000000003108747316
    Journal: Cell Transplant
    E-pub date: 1 Oct 2003
    Authors: C Watts, T Donovan, JH Gillard, NM Antoun, R Burnstein, DK Menon, TA Carpenter, T Fryer, DGT Thomas, JD Pickard

    Assessment of cerebrovascular autoregulation in head-injured patients: a validation study.

    DOI: http://doi.org/10.1161/01.STR.0000089014.59668.04
    Journal: Stroke
    E-pub date: 1 Oct 2003
    Authors: LA Steiner, JP Coles, AJ Johnston, DA Chatfield, P Smielewski, TD Fryer, FI Aigbirhio, JC Clark, JD Pickard, DK Menon, M Czosnyka

    Cerebrovascular pressure reactivity is related to global cerebral oxygen metabolism after head injury.

    DOI: http://doi.org/10.1136/jnnp.74.6.765
    Journal: J Neurol Neurosurg Psychiatry
    E-pub date: 1 Jun 2003
    Authors: LA Steiner, JP Coles, M Czosnyka, PS Minhas, TD Fryer, FI Aigbirhio, JC Clark, P Smielewski, DA Chatfield, T Donovan, JD Pickard, DK Menon

    Integrated image analysis solutions for PET datasets in damaged brain.

    DOI: http://doi.org/10.1023/a:1026293611455
    Journal: J Clin Monit Comput
    E-pub date: 1 Dec 2002
    Authors: P Smielewski, JP Coles, TD Fryer, PS Minhas, DK Menon, JD Pickard

    Effect of hyperventilation on cerebral blood flow in traumatic head injury: clinical relevance and monitoring correlates.

    DOI: http://doi.org/10.1097/00003246-200209000-00002
    Journal: Crit Care Med
    E-pub date: 1 Sep 2002
    Authors: JP Coles, PS Minhas, TD Fryer, P Smielewski, F Aigbirihio, T Donovan, SPMJ Downey, G Williams, D Chatfield, JC Matthews, AK Gupta, TA Carpenter, JC Clark, JD Pickard, DK Menon

    Detecting residual cognitive function in persistent vegetative state.

    DOI: http://doi.org/10.1076/neur.8.4.394.16184
    Journal: Neurocase
    E-pub date: 1 Aug 2002
    Authors: AM Owen, DK Menon, IS Johnsrude, D Bor, SK Scott, T Manly, EJ Williams, C Mummery, JD Pickard

    Ischaemic Burden following Traumatic Brain Injury: Monitoring Correlates and Relevance to Outcome

    DOI: http://doi.org/10.1042/cs103062p
    Journal: Clinical Science
    E-pub date: 1 Jul 2002
    Authors: JP Coles, TD Fryer, DA Parry, P Smieleswiksi, J Matthews, T Donovan, D Day, F Aigbrhio, JC Clark, JD Pickard, DK Menon

    Correlation between cerebral blood flow, substrate delivery, and metabolism in head injury: a combined microdialysis and triple oxygen positron emission tomography study.

    DOI: http://doi.org/10.1097/00004647-200206000-00012
    Journal: J Cereb Blood Flow Metab
    E-pub date: 1 Jun 2002
    Authors: PJ Hutchinson, AK Gupta, TF Fryer, PG Al-Rawi, DA Chatfield, JP Coles, MT O'Connell, R Kett-White, PS Minhas, FI Aigbirhio, JC Clark, PJ Kirkpatrick, DK Menon, JD Pickard

    Measurement of brain tissue oxygenation performed using positron emission tomography scanning to validate a novel monitoring method.

    DOI: http://doi.org/10.3171/jns.2002.96.2.0263
    Journal: J Neurosurg
    E-pub date: 1 Feb 2002
    Authors: AK Gupta, PJ Hutchinson, T Fryer, PG Al-Rawi, DA Parry, PS Minhas, R Kett-White, PJ Kirkpatrick, JC Mathews, S Downey, F Aigbirhio, J Clark, JD Pickard, DK Menon

    Potential role of NovoSeven in the prevention of rebleeding following aneurysmal subarachnoid haemorrhage.

    DOI: http://doi.org/10.1097/00001721-200004001-00022
    Journal: Blood Coagul Fibrinolysis
    E-pub date: 1 Apr 2000
    Authors: JD Pickard, PJ Kirkpatrick, T Melsen, RB Andreasen, L Gelling, T Fryer, J Matthews, P Minhas, PJ Hutchinson, D Menon, SP Downey, I Kendall, J Clark, TA Carpenter, E Williams, L Persson