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EMAIL sharon.morein@aru.ac.uk
Department
  • Psychology
    • Institute
  • Behavioural and Clinical Neuroscience Institute
    • Click to view home page
    Research Theme Lifelong Brain Development and Brain Ageing The Social Brain Neurons, Circuits and Networks
    Research Focus

    Keywords

  • Action Inhibition

    • Clinical Conditions

  • Obsessive compulsive disorder
  • Attention deficit hyperactivity disorder

    • Equipment & Techniques

  • Behavioural analysis
  • Cross-sectional and cohort studies

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    Dr Sharon Morein

    University Position
    Associate Professor

    Interests

    My research integrates approaches from psychology, psychiatry and cognitive neuroscience to better understand and enable more effective interventions and ultimately prevention of mental health conditions relating to compulsivity and impulsivity (primarily Hoarding Disorder, Obsessive Compulsive Disorder and Attention Deficit Hyperactivity Disorder). I study how people control their actions and inhibit or change them when the behaviours are deemed no longer appropriate or disruptive. I also investigate how learning mechanisms can contribute to maladaptive behaviours.

    Collaborators

    Cambridge
  • Amy Milton
  • Trevor Robbins

    • Key Publications

    The profile of executive function in OCD hoarders and hoarding disorder.

    DOI: http://doi.org/10.1016/j.psychres.2013.12.026
    Journal: Psychiatry Research
    E-pub date: 30 Mar 2014
    Authors: S Morein-Zamir, M Papmeyer, A Pertusa, SR Chamberlain, NA Fineberg, BJ Sahakian, D Mataix-Cols, TW Robbins

    Publications

    Fronto-striatal circuits in response-inhibition: Relevance to addiction.

    DOI: http://doi.org/10.1016/j.brainres.2014.09.012
    Journal: Brain Res
    E-pub date: 2 Dec 2015
    Authors: S Morein-Zamir, TW Robbins

    Counterfactual processing of economic action-outcome alternatives in obsessive-compulsive disorder: further evidence of impaired goal-directed behavior.

    DOI: http://doi.org/10.1016/j.biopsych.2013.01.018
    Journal: Biological Psychiatry
    E-pub date: 15 Apr 2014
    Authors: CM Gillan, S Morein-Zamir, M Kaser, NA Fineberg, A Sule, BJ Sahakian, RN Cardinal, TW Robbins

    Prefrontal hypoactivity associated with impaired inhibition in stimulant-dependent individuals but evidence for hyperactivation in their unaffected siblings.

    DOI: http://doi.org/10.1038/npp.2013.90
    Journal: Neuropsychopharmacology
    E-pub date: 1 Sep 2013
    Authors: S Morein-Zamir, P Simon Jones, ET Bullmore, TW Robbins, KD Ersche

    Investigation of attentional bias in obsessive compulsive disorder with and without depression in visual search.

    DOI: http://doi.org/10.1371/journal.pone.0080118
    Journal: PLoS One
    E-pub date: 1 Aug 2013
    Authors: S Morein-Zamir, M Papmeyer, A Durieux, NA Fineberg, BJ Sahakian, TW Robbins

    Punishment promotes response control deficits in obsessive-compulsive disorder: evidence from a motivational go/no-go task.

    DOI: http://doi.org/10.1017/S0033291712001018
    Journal: Psychol Med
    E-pub date: 1 Feb 2013
    Authors: S Morein-Zamir, M Papmeyer, CM Gillan, MJ Crockett, NA Fineberg, BJ Sahakian, TW Robbins

    Serotonin modulates the effects of Pavlovian aversive predictions on response vigor.

    DOI: http://doi.org/10.1038/npp.2012.75
    Journal: Neuropsychopharmacology
    E-pub date: 1 Sep 2012
    Authors: MJ Crockett, L Clark, AM Apergis-Schoute, S Morein-Zamir, TW Robbins

    Disruption in the balance between goal-directed behavior and habit learning in obsessive-compulsive disorder.

    DOI: http://doi.org/10.1176/appi.ajp.2011.10071062
    Journal: Am J Psychiatry
    E-pub date: 1 Jul 2011
    Authors: CM Gillan, M Papmeyer, S Morein-Zamir, BJ Sahakian, NA Fineberg, TW Robbins, S de Wit

    Abnormal structure of frontostriatal brain systems is associated with aspects of impulsivity and compulsivity in cocaine dependence.

    DOI: http://doi.org/10.1093/brain/awr138
    Journal: Brain
    E-pub date: 1 Jul 2011
    Authors: KD Ersche, A Barnes, PS Jones, S Morein-Zamir, TW Robbins, ET Bullmore

    Hippocampal dysfunction in patients with mild cognitive impairment: a functional neuroimaging study of a visuospatial paired associates learning task.

    DOI: http://doi.org/10.1016/j.neuropsychologia.2011.03.037
    Journal: Neuropsychologia
    E-pub date: 1 Jun 2011
    Authors: M de Rover, VA Pironti, JA McCabe, J Acosta-Cabronero, FS Arana, S Morein-Zamir, JR Hodges, TW Robbins, PC Fletcher, PJ Nestor, BJ Sahakian

    Dissociating inhibition, attention, and response control in the frontoparietal network using functional magnetic resonance imaging.

    DOI: http://doi.org/10.1093/cercor/bhq187
    Journal: Cereb Cortex
    E-pub date: 1 May 2011
    Authors: CM Dodds, S Morein-Zamir, TW Robbins

    Neuroethical issues in cognitive enhancement.

    DOI: http://doi.org/10.1177/0269881109106926
    Journal: J Psychopharmacol
    E-pub date: 1 Feb 2011
    Authors: BJ Sahakian, S Morein-Zamir

    Impaired visuospatial associative memory and attention in obsessive compulsive disorder but no evidence for differential dopaminergic modulation.

    DOI: http://doi.org/10.1007/s00213-010-1963-z
    Journal: Psychopharmacology (Berl)
    E-pub date: 1 Oct 2010
    Authors: S Morein-Zamir, KJ Craig, KD Ersche, S Abbott, U Muller, NA Fineberg, ET Bullmore, BJ Sahakian, TW Robbins

    Inhibition of thoughts and actions in obsessive-compulsive disorder: extending the endophenotype?

    DOI: http://doi.org/10.1017/S003329170999033X
    Journal: Psychol Med
    E-pub date: 1 Feb 2010
    Authors: S Morein-Zamir, NA Fineberg, TW Robbins, BJ Sahakian

    Neuroethics and public engagement training needed for neuroscientists.

    DOI: http://doi.org/10.1016/j.tics.2009.10.007
    Journal: Trends Cogn Sci
    E-pub date: 1 Feb 2010
    Authors: S Morein-Zamir, BJ Sahakian

    Neuroscientists need neuroethics teaching.

    DOI: http://doi.org/10.1126/science.325_147a
    Journal: Science
    E-pub date: 10 Jul 2009
    Authors: BJ Sahakian, S Morein-Zamir

    Novel measures of response performance and inhibition in children with ADHD.

    DOI: http://doi.org/10.1007/s10802-008-9243-7
    Journal: J Abnorm Child Psychol
    E-pub date: 1 Nov 2008
    Authors: S Morein-Zamir, P Hommersen, C Johnston, A Kingstone

    Professor’s little helper.

    DOI: http://doi.org/10.1038/4501157a
    Journal: Nature
    E-pub date: 20 Dec 2007
    Authors: B Sahakian, S Morein-Zamir

    A review of the effects of modafinil on cognition in schizophrenia.

    DOI: http://doi.org/10.1093/schbul/sbm090
    Journal: Schizophr Bull
    E-pub date: 1 Nov 2007
    Authors: S Morein-Zamir, DC Turner, BJ Sahakian

    Predictability influences stopping and response control.

    DOI: http://doi.org/10.1037/0096-1523.33.1.149
    Journal: J Exp Psychol Hum Percept Perform
    E-pub date: 1 Feb 2007
    Authors: S Morein-Zamir, R Chua, I Franks, P Nagelkerke, A Kingstone

    Compatibility effects in stopping and response initiation in a continuous tracking task.

    DOI: http://doi.org/10.1080/17470210500416375
    Journal: Q J Exp Psychol (Hove)
    E-pub date: 1 Dec 2006
    Authors: S Morein-Zamir, P Nagelkerke, R Chua, I Franks, A Kingstone

    Fixation offset and stop signal intensity effects on saccadic countermanding: a crossmodal investigation.

    DOI: http://doi.org/10.1007/s00221-006-0564-x
    Journal: Exp Brain Res
    E-pub date: 1 Nov 2006
    Authors: S Morein-Zamir, A Kingstone

    Measuring online volitional response control with a continuous tracking task.

    DOI: http://doi.org/10.3758/bf03193896
    Journal: Behav Res Methods
    E-pub date: 1 Nov 2006
    Authors: S Morein-Zamir, R Chua, I Franks, P Nagelkerke, A Kingstone

    Differential processing of word and color in unilateral spatial neglect.

    DOI: http://doi.org/10.1016/j.cogbrainres.2004.10.013
    Journal: Brain Res Cogn Brain Res
    E-pub date: 1 May 2005
    Authors: S Morein-Zamir, A Henik, M Balas, N Soroker

    On audiovisual spatial synergy: the fragility of the phenomenon.

    DOI: http://doi.org/10.3758/bf03193323
    Journal: Percept Psychophys
    E-pub date: 1 Apr 2005
    Authors: S Soto-Faraco, S Morein-Zamir, A Kingstone

    Inhibiting prepared and ongoing responses: is there more than one kind of stopping?

    DOI: http://doi.org/10.3758/bf03196733
    Journal: Psychon Bull Rev
    E-pub date: 1 Dec 2004
    Authors: S Morein-Zamir, P Nagelkerke, R Chua, I Franks, A Kingstone

    Executive functioning in boys with ADHD: primarily an inhibition deficit?

    DOI: http://doi.org/10.1016/j.acn.2003.08.005
    Journal: Arch Clin Neuropsychol
    E-pub date: 1 Jun 2004
    Authors: A Scheres, J Oosterlaan, H Geurts, S Morein-Zamir, N Meiran, H Schut, L Vlasveld, JA Sergeant

    Auditory capture of vision: examining temporal ventriloquism.

    DOI: http://doi.org/10.1016/s0926-6410(03)00089-2
    Journal: Brain Res Cogn Brain Res
    E-pub date: 1 Jun 2003
    Authors: S Morein-Zamir, S Soto-Faraco, A Kingstone

    Individual stopping times and cognitive control: converging evidence for the stop signal task from a continuous tracking paradigm.

    DOI: http://doi.org/10.1080/02724980244000495
    Journal: Q J Exp Psychol A
    E-pub date: 1 Apr 2003
    Authors: S Morein-Zamir, N Meiran

    The effect of methylphenidate on three forms of response inhibition in boys with AD/HD.

    DOI: http://doi.org/10.1023/a:1021729501230
    Journal: J Abnorm Child Psychol
    E-pub date: 1 Feb 2003
    Authors: A Scheres, J Oosterlaan, J Swanson, S Morein-Zamir, N Meiran, H Schut, L Vlasveld, JA Sergeant

    Orienting attention in aging and Parkinson’s disease: distinguishing modes of control.

    DOI: http://doi.org/10.1076/jcen.24.7.951.8387
    Journal: J Clin Exp Neuropsychol
    E-pub date: 1 Oct 2002
    Authors: A Kingstone, R Klein, S Morein-Zamir, A Hunt, J Fisk, C Maxner

    The importance of irrelevant-dimension variability in the stroop flanker task.

    DOI: http://doi.org/10.3758/bf03196266
    Journal: Psychon Bull Rev
    E-pub date: 1 Mar 2002
    Authors: S Morein-Zamir, A Henik, I Spitzer-Davidson