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EMAIL sr773@cam.ac.uk
Department
  • Medicine
    • Institute
  • Division of Anaesthesia
    • Click to view home page
    Research Theme Neurons, Circuits and Networks Lifelong Brain Development and Brain Ageing
    Research Focus

    Keywords

  • Traumatic Brain Injury
  • Emergency Medicine
  • Prevention
  • Neurotrauma
  • Diffusion MRI
  • Biomarkers

    • Clinical Conditions

  • Traumatic brain injury
  • Dementia

    • Equipment & Techniques

  • Cross-sectional and cohort studies
  • Magnetic resonance imaging (MRI)
  • Neuropsychological testing
  • Statistical analysis
  • Computerised tomography

    • Science Culture

  • Women in Neuroscience
  • Mentorship
  • Reproducibility in Science
  • Teaching
  • Open Access

    • Back

    Dr Sophie Richter

    (she/her/hers)
    University Position
    Clinical Lecturer
    Dr Sophie Richter is pleased to consider applications from prospective PhD students.

    Interests

    Sophie is an NIHR Clinical Lecturer in Emergency Medicine. Her research focuses on the development of decision tools for the prognosis and management of traumatic brain injury in the emergency setting. Her previous research has concentrated on using circulating blood biomarkers and advanced imaging techniques (such as quantitative MRI) for this purpose. She is also investigating the link between traumatic brain injury and subsequent risk of neurodegeneration and dementia. This is closely intertwined with her interest in methodological research including for example the handling of missing data and data harmonization. Full list of publications: https://orcid.org/0000-0003-3272-484X

    Collaborators

    Cambridge
  • Virginia Newcombe
  • David Menon
  • Marta Morgado Correia
  • Guy Williams
  • Stefan Winzeck

    • Key Publications

    Acute thalamic connectivity precedes chronic post-concussive symptoms in mild traumatic brain injury.

    DOI: http://doi.org/10.1093/brain/awad056
    Journal: Brain
    E-pub date: 1 Aug 2023
    Authors: RE Woodrow, S Winzeck, AI Luppi, IR Kelleher-Unger, LRB Spindler, JTL Wilson, VFJ Newcombe, JP Coles, CENTER-TBI MRI Substudy Participants and Investigators, DK Menon, EA Stamatakis

    Serum biomarkers identify critically ill traumatic brain injury patients for MRI

    DOI: http://doi.org/10.1186/s13054-022-04250-3
    Journal: Critical Care
    E-pub date: 29 Nov 2022
    Authors: S Richter, S Winzeck, E Czeiter, K Amrein, EN Kornaropoulos, J Verheyden, G Sugar, Z Yang, K Wang, AIR Maas, E Steyerberg, A Büki, VFJ Newcombe, DK Menon, K Amrein, N Andelic, L Andreassen, A Anke, P Azouvi, B Bellander, H Benali, A Buki, A Caccioppola, E Calappi, M Carbonara, G Citerio, H Clusmann, M Coburn, J Coles, M Correia, E Czeiter, V De Keyser, V Degos, B Depreitere, L Eikenes, E Ezer, K Foks, S Frisvold, D Galanaud, A Ghuysen, B Glocker, A Haberg, I Haitsma, E Helseth, PJ Hutchinson, E Kornaropoulos, N Kovács, A Kowark, S Laureys, D Ledoux, H Lingsma, AIR Maas, G Manley, DK Menon, T Menovsky, B Misset, V Muraleedharan, I Nakken, V Newcombe, W Nordhøy, J Nyirádi, F Ortolano, PM Parizel, V Perlbarg, P Persona, W Peul, JP Posti, L Puybasset, S Richter, C Roe, O Roise, R Rossaint, S Rossi, D Rueckert, T Skandsen, A Sorinola, E Stamatakis, EW Steyerberg, N Stocchetti, R Takala, V Tamás, O Tenovuo, Z Vámos, G Van der Steen, W Van Hecke, TV Vyvere, J Verheyden, A Vik, V Volovici, LT Westlye, G Williams, S Winzeck, P Ylén, T Zoerle

    Neuroanatomical Substrates and Symptoms Associated With Magnetic Resonance Imaging of Patients With Mild Traumatic Brain Injury.

    DOI: http://doi.org/10.1001/jamanetworkopen.2021.0994
    Journal: JAMA Netw Open
    E-pub date: 1 Mar 2021
    Authors: S Richter, S Winzeck, EN Kornaropoulos, T Das, T Vande Vyvere, J Verheyden, GB Williams, MM Correia, DK Menon, VFJ Newcombe, Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Magnetic Resonance Imaging (CENTER-TBI MRI) Substudy Participants and Investigators

    Handling of Missing Outcome Data in Traumatic Brain Injury Research: A Systematic Review.

    DOI: http://doi.org/10.1089/neu.2018.6216
    Journal: J Neurotrauma
    E-pub date: 1 Oct 2019
    Authors: S Richter, S Stevenson, T Newman, L Wilson, DK Menon, AIR Maas, D Nieboer, H Lingsma, EW Steyerberg, VFJ Newcombe

    Publications

    Fluid biomarkers and neuroimaging in mild traumatic brain injury: current uses and potential future directions for clinical use in emergency medicine.

    DOI: http://doi.org/10.1136/emermed-2023-213111
    Journal: Emerg Med J
    E-pub date: 1 Sep 2023
    Authors: V Newcombe, S Richter, DP Whitehouse, BM Bloom, F Lecky

    Comparison of ComBat harmonization methods for longitudinal magnetic resonance imaging data in a travelling subject cohort

    DOI: http://doi.org/10.58530/2022/1916
    Journal: ISMRM Annual Meeting
    E-pub date: 3 Aug 2023
    Authors: S Richter, S Winzeck, M Correia, E Kornaropoulos, A Manktelow, J Outtrim, D Chatfield, J Posti, O Tenovuo, G Williams, D Menon, V Newcombe

    Impact of Diffusion Signal Harmonisation on Voxel-Wise Analysis of Mild Traumatic Brain Injury

    DOI: http://doi.org/10.58530/2022/1257
    Journal: ISMRM Annual Meeting
    E-pub date: 3 Aug 2023
    Authors: S Winzeck, S Richter, MS Pinto, E Kornaropoulos, V Newcombe, B Glocker, D Menon, M Correia

    Serum lipidome associates with neuroimaging features in patients with traumatic brain injury

    DOI: http://doi.org/10.1101/2023.03.14.23287262
    Journal:
    E-pub date: 1 Aug 2023
    Authors: I Thomas, VFJ Newcombe, AM Dickens, S Richter, JP Posti, AIR Maas, O Tenovuo, T Hyötyläinen, A Büki, DK Menon, M Orešič

    Use of Support Vector Machines Approach via ComBat Harmonized Diffusion Tensor Imaging for the Diagnosis and Prognosis of Mild Traumatic Brain Injury: A CENTER-TBI Study.

    DOI: http://doi.org/10.1089/neu.2022.0365
    Journal: J Neurotrauma
    E-pub date: 1 Jul 2023
    Authors: M Siqueira Pinto, S Winzeck, EN Kornaropoulos, S Richter, R Paolella, MM Correia, B Glocker, G Williams, A Vik, JP Posti, A Haberg, J Stenberg, P-J Guns, AJ den Dekker, DK Menon, J Sijbers, P Van Dyck, VFJ Newcombe

    Validation of cross-sectional and longitudinal ComBat harmonization methods for magnetic resonance imaging data on a travelling subject cohort.

    DOI: http://doi.org/10.1016/j.ynirp.2022.100136
    Journal: Neuroimage Rep
    E-pub date: 1 Dec 2022
    Authors: S Richter, S Winzeck, MM Correia, EN Kornaropoulos, A Manktelow, J Outtrim, D Chatfield, JP Posti, O Tenovuo, GB Williams, DK Menon, VFJ Newcombe

    Journal update monthly top five.

    DOI: http://doi.org/10.1136/emermed-2022-212922
    Journal: Emerg Med J
    E-pub date: 1 Dec 2022
    Authors: L Barrett, O Hibberd, DP Whitehouse, T Adams, J Price, S Richter, EBG Barnard, AJN Jafar

    Journal update monthly top five.

    DOI: http://doi.org/10.1136/emermed-2021-212197
    Journal: Emerg Med J
    E-pub date: 1 Jan 2022
    Authors: L Barrett, T Adams, DP Whitehouse, S Richter, AA Boyle, V Newcombe

    Study Design Features Associated with Patient Attrition in Studies of Traumatic Brain Injury: A Systematic Review.

    DOI: http://doi.org/10.1089/neu.2020.7000
    Journal: J Neurotrauma
    E-pub date: 1 Sep 2020
    Authors: S Richter, S Stevenson, T Newman, L Wilson, AIR Maas, D Nieboer, H Lingsma, EW Steyerberg, VFJ Newcombe

    Blood biomarkers on admission in acute traumatic brain injury: Relations to severity, CT findings and care path in the CENTER-TBI study.

    DOI: http://doi.org/10.1016/j.ebiom.2020.102785
    Journal: EBioMedicine
    E-pub date: 1 Jun 2020
    Authors: E Czeiter, K Amrein, BY Gravesteijn, F Lecky, DK Menon, S Mondello, VFJ Newcombe, S Richter, EW Steyerberg, TV Vyvere, J Verheyden, H Xu, Z Yang, AIR Maas, KKW Wang, A Büki, CENTER-TBI Participants and Investigators

    Validation of the short form of the International Crowding Measure in Emergency Departments: an international study.

    DOI: http://doi.org/10.1097/MEJ.0000000000000579
    Journal: Eur J Emerg Med
    E-pub date: 1 Dec 2019
    Authors: A Boyle, P Atkinson, C Basaure Verdejo, E Chan, R Clouston, P Gilligan, K Grewal, I Higginson, P Liston, V Newcombe, V Norton, S Richter, G Stoica, A Wakai

    VALIDATION OF THE SHORT FORM OF THE INTERNATIONAL CROWDING MEASURE IN EMERGENCY DEPARTMENTS (ICMED): INTERNATIONAL STUDY

    DOI: http://doi.org/10.1136/emermed-2016-206402.12
    Journal: Emergency Medicine Journal
    E-pub date: 1 Dec 2016
    Authors: A Boyle, S Richter, P Atkinson, R Clouston, G Stoica, C Basaure Verdejo, A Wakai, E Chan, K Grewal, P Gilligan, I Higginson, P Liston, V Newcombe, V Norton

    WHAT SHOULD BE DONE TO REDUCE EMERGENCY DEPARTMENT CROWDING? – A DELPHI STUDY

    DOI: http://doi.org/10.1136/emermed-2016-206402.30
    Journal: Emergency Medicine Journal
    E-pub date: 1 Dec 2016
    Authors: E MacDonald-Nethercott, S Richter, A Boyle, I Higginson

    Capillary blood gas as a substitute for arterial blood gas: a meta-analysis.

    DOI: http://doi.org/10.12968/hmed.2014.75.3.136
    Journal: Br J Hosp Med (Lond)
    E-pub date: 1 Mar 2014
    Authors: S Richter, C Kerry, N Hassan, A Chari, D Lunn, A Nickol