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Department
  • Psychology
    • Institute
  • Autism Research Centre
    • Research Theme Lifelong Brain Development and Brain Ageing The Social Brain Neurons, Circuits and Networks
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    Dr Varun Warrier

    University Position
    Assistant Professor

    Interests

    My team works on social and genetic factors that influence neurodevelopment, and mental health. We have a particular interest in investigating heterogeneity in outcomes to develop targeted support and therapy for those who need it. This publication list is not up to date. Please see my google scholar page for the most up-to-date list of publications: https://scholar.google.co.uk/citations?user=_f3ym2cAAAAJ&hl=en

    Associated News Items

    Key Publications

    Genetic correlates of phenotypic heterogeneity in autism.

    DOI: http://doi.org/10.1038/s41588-022-01072-5
    Journal: Nat Genet
    E-pub date: 1 Sep 2022
    Authors: V Warrier, X Zhang, P Reed, A Havdahl, TM Moore, F Cliquet, CS Leblond, T Rolland, A Rosengren, EU-AIMS LEAP, iPSYCH-Autism Working Group, Spectrum 10K and APEX Consortia, DH Rowitch, ME Hurles, DH Geschwind, AD Børglum, EB Robinson, J Grove, HC Martin, T Bourgeron, S Baron-Cohen

    Testing the Empathizing-Systemizing theory of sex differences and the Extreme Male Brain theory of autism in half a million people.

    DOI: http://doi.org/10.1073/pnas.1811032115
    Journal: Proc Natl Acad Sci U S A
    E-pub date: 27 Nov 2018
    Authors: DM Greenberg, V Warrier, C Allison, S Baron-Cohen

    Publications

    Genetic insights into human cortical organization and development through genome-wide analyses of 2,347 neuroimaging phenotypes.

    DOI: http://doi.org/10.1038/s41588-023-01475-y
    Journal: NATURE GENETICS
    E-pub date: 1 Aug 2023
    Authors: V Warrier, E-M Stauffer, QQ Huang, EM Wigdor, EAW Slob, J Seidlitz, L Ronan, SL Valk, TT Mallard, AD Grotzinger, R Romero-Garcia, S Baron-Cohen, DH Geschwind, MA Lancaster, GK Murray, MJ Gandal, A Alexander-Bloch, H Won, HC Martin, ET Bullmore, RAI Bethlehem

    The effect of autistic traits on disembedding and mental rotation in neurotypical women and men.

    DOI: http://doi.org/10.1038/s41598-022-08497-2
    Journal: Sci Rep
    E-pub date: 17 Mar 2022
    Authors: M Conson, VP Senese, I Zappullo, C Baiano, V Warrier, LabNPEE Group, S Raimo, B Rauso, S Salzano, S Baron-Cohen

    Childhood trauma, life-time self-harm, and suicidal behaviour and ideation are associated with polygenic scores for autism.

    DOI: http://doi.org/10.1038/s41380-019-0550-x
    Journal: Mol Psychiatry
    E-pub date: 1 May 2021
    Authors: V Warrier, S Baron-Cohen

    Increased prevalence of non-communicable physical health conditions among autistic adults.

    DOI: http://doi.org/10.1177/1362361320953652
    Journal: Autism
    E-pub date: 1 Apr 2021
    Authors: E Weir, C Allison, V Warrier, S Baron-Cohen

    Elevated rates of autism, other neurodevelopmental and psychiatric diagnoses, and autistic traits in transgender and gender-diverse individuals.

    DOI: http://doi.org/10.1038/s41467-020-17794-1
    Journal: Nat Commun
    E-pub date: 7 Aug 2020
    Authors: V Warrier, DM Greenberg, E Weir, C Buckingham, P Smith, M-C Lai, C Allison, S Baron-Cohen

    The effects of autistic traits and academic degree on visuospatial abilities.

    DOI: http://doi.org/10.1007/s10339-019-00941-y
    Journal: Cogn Process
    E-pub date: 1 Feb 2020
    Authors: M Conson, VP Senese, C Baiano, I Zappullo, V Warrier, UNICAMPSY17 group, S Salzano, M Positano, S Baron-Cohen

    Social and non-social autism symptoms and trait domains are genetically dissociable.

    DOI: http://doi.org/10.1038/s42003-019-0558-4
    Journal: Commun Biol
    E-pub date: 3 Sep 2019
    Authors: V Warrier, R Toro, H Won, CS Leblond, F Cliquet, R Delorme, W De Witte, J Bralten, B Chakrabarti, AD Børglum, J Grove, G Poelmans, DA Hinds, T Bourgeron, S Baron-Cohen

    The oxytocin receptor gene predicts brain activity during an emotion recognition task in autism

    DOI: http://doi.org/10.1186/s13229-019-0258-4
    Journal: Mol Autism
    E-pub date: 1 Aug 2019
    Authors: F Uzefovsky, R Bethlehem, S Shamay-Tsoory, A Ruigrok, R Holt, M Spencer, L Chura, V Warrier, B Chakrabarti, E Bullmore, J Suckling, D Floris, S Baron-Cohen, J Davis

    Integrated genetic and methylomic analyses identify shared biology between autism and autistic traits.

    DOI: http://doi.org/10.1186/s13229-019-0279-z
    Journal: Mol Autism
    E-pub date: 1 Aug 2019
    Authors: A Massrali, H Brunel, E Hannon, C Wong, iPSYCH-MINERvA Epigenetics Group, S Baron-Cohen, V Warrier

    SOCIAL AND NON-SOCIAL DOMAINS OF AUTISM ARE GENETICALLY DISSOCIABLE

    DOI: http://doi.org/10.1016/j.euroneuro.2018.08.241
    Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
    E-pub date: 1 Aug 2019
    Authors: V Warrier, R Toro, B Chakrabarti, H Won, A Borglum, J Grove, DA Hinds, T Bourgeron, S Baron-Cohen

    AUTISM POLYGENIC SCORES ARE ASSOCIATED WITH CHILDHOOD MALTREATMENT AND LIFETIME SELF-HARM BEHAVIOUR AND IDEATION

    DOI: http://doi.org/10.1016/j.euroneuro.2019.07.209
    Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
    E-pub date: 1 Aug 2019
    Authors: V Warrier, S Baron-Cohen

    Reply to Perrykkad and Hohwy: When big data are the answer.

    DOI: http://doi.org/10.1073/pnas.1903773116
    Journal: Proc Natl Acad Sci U S A
    E-pub date: 9 Jul 2019
    Authors: DM Greenberg, V Warrier, C Allison, S Baron-Cohen

    Synaptic and transcriptionally downregulated genes are associated with cortical thickness differences in autism.

    DOI: http://doi.org/10.1038/s41380-018-0023-7
    Journal: Mol Psychiatry
    E-pub date: 1 Jul 2019
    Authors: R Romero-Garcia, V Warrier, ET Bullmore, S Baron-Cohen, RAI Bethlehem

    Mapping genotype to phenotype in neurodevelopmental copy number variants.

    DOI: http://doi.org/10.1016/S2215-0366(19)30163-4
    Journal: Lancet Psychiatry
    E-pub date: 1 Jun 2019
    Authors: V Warrier, S Baron-Cohen

    The epigenetics of autism

    DOI: http://doi.org/10.1016/B978-0-12-813796-3.00013-4
    Journal:
    E-pub date: 1 Jan 2019
    Authors: A Massrali, V Warrier, A Paul, D Adhya, DP Srivastava, M Kotter, S Baron-Cohen

    Genome-wide meta-analysis of cognitive empathy: heritability, and correlates with sex, neuropsychiatric conditions and cognition.

    DOI: http://doi.org/10.1038/mp.2017.122
    Journal: Mol Psychiatry
    E-pub date: 1 Jun 2018
    Authors: V Warrier, KL Grasby, F Uzefovsky, R Toro, P Smith, B Chakrabarti, J Khadake, E Mawbey-Adamson, N Litterman, J-J Hottenga, G Lubke, DI Boomsma, NG Martin, PK Hatemi, SE Medland, DA Hinds, T Bourgeron, S Baron-Cohen

    Genome-wide analyses of self-reported empathy: correlations with autism, schizophrenia, and anorexia nervosa.

    DOI: http://doi.org/10.1038/s41398-017-0082-6
    Journal: Transl Psychiatry
    E-pub date: 12 Mar 2018
    Authors: V Warrier, R Toro, B Chakrabarti, iPSYCH-Broad autism group, AD Børglum, J Grove, 23andMe Research Team, DA Hinds, T Bourgeron, S Baron-Cohen

    Genetic contribution to ‘theory of mind’ in adolescence.

    DOI: http://doi.org/10.1038/s41598-018-21737-8
    Journal: Sci Rep
    E-pub date: 22 Feb 2018
    Authors: V Warrier, S Baron-Cohen

    THE OXYTOCIN RECEPTOR INTERACTS WITH AUTISM DIAGNOSIS TO PREDICT BRAIN ACTIVATION IN RESPONSE TO THE EYES TEST

    DOI: http://doi.org/10.1016/j.euroneuro.2016.09.403
    Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
    E-pub date: 1 Aug 2017
    Authors: F Uzefovsky, R Bethlehem, S Shamay-Tsoory, A Ruigrok, R Holt, M Spencer, L Chura, V Warrier, B Chakrabarti, E Bullmore, J Suckling, D Floris, S Baron-Cohen

    A META-ANALYSIS OF COGNITIVE EMPATHY: HERITABILITY AND CORRELATES OF THE ‘READING THE MIND IN THE EYES’ TEST WITH PSYCHIATRIC CONDITIONS, PSYCHOLOGICAL TRAITS AND SUBCORTICAL VOLUMES

    DOI: http://doi.org/10.1016/j.euroneuro.2016.09.608
    Journal: EUROPEAN NEUROPSYCHOPHARMACOLOGY
    E-pub date: 1 Aug 2017
    Authors: V Warrier, K Grasby, F Uzefovsky, R Toro, P Smith, B Chakrabarti, J Khadake, E Mawbey-Adamson, N Litterman, J-J Hottenga, G Lubke, D Boomsma, NG Martin, PK Hatemi, S Medland, DA Hinds, T Bourgeron, S Baron-Cohen

    Genetic variant rs17225178 in the ARNT2 gene is associated with Asperger Syndrome.

    DOI: http://doi.org/10.1186/s13229-015-0009-0
    Journal: Mol Autism
    E-pub date: 1 Aug 2015
    Authors: A Di Napoli, V Warrier, S Baron-Cohen, B Chakrabarti

    A Pooled Genome-Wide Association Study of Asperger Syndrome.

    DOI: http://doi.org/10.1371/journal.pone.0131202
    Journal: PLoS One
    E-pub date: 1 Aug 2015
    Authors: V Warrier, B Chakrabarti, L Murphy, A Chan, I Craig, U Mallya, S Lakatošová, K Rehnstrom, L Peltonen, S Wheelwright, C Allison, SE Fisher, S Baron-Cohen

    A comprehensive meta-analysis of common genetic variants in autism spectrum conditions.

    DOI: http://doi.org/10.1186/s13229-015-0041-0
    Journal: Mol Autism
    E-pub date: 1 Aug 2015
    Authors: V Warrier, V Chee, P Smith, B Chakrabarti, S Baron-Cohen

    A genome wide association study of mathematical ability reveals an association at chromosome 3q29, a locus associated with autism and learning difficulties: a preliminary study.

    DOI: http://doi.org/10.1371/journal.pone.0096374
    Journal: PLoS One
    E-pub date: 1 Aug 2014
    Authors: S Baron-Cohen, L Murphy, B Chakrabarti, I Craig, U Mallya, S Lakatošová, K Rehnstrom, L Peltonen, S Wheelwright, C Allison, SE Fisher, V Warrier

    Genetic variation in the oxytocin receptor (OXTR) gene is associated with Asperger Syndrome.

    DOI: http://doi.org/10.1186/2040-2392-5-48
    Journal: Mol Autism
    E-pub date: 1 Aug 2014
    Authors: A Di Napoli, V Warrier, S Baron-Cohen, B Chakrabarti

    Single nucleotide polymorphism rs6716901 in SLC25A12 gene is associated with Asperger syndrome.

    DOI: http://doi.org/10.1186/2040-2392-5-25
    Journal: Mol Autism
    E-pub date: 31 Mar 2014
    Authors: J Durdiaková, V Warrier, S Baron-Cohen, B Chakrabarti

    STX1A and Asperger syndrome: a replication study.

    DOI: http://doi.org/10.1186/2040-2392-5-14
    Journal: Mol Autism
    E-pub date: 18 Feb 2014
    Authors: J Durdiaková, V Warrier, S Banerjee-Basu, S Baron-Cohen, B Chakrabarti

    Genetic variation in GABRB3 is associated with Asperger syndrome and multiple endophenotypes relevant to autism.

    DOI: http://doi.org/10.1186/2040-2392-4-48
    Journal: Mol Autism
    E-pub date: 9 Dec 2013
    Authors: V Warrier, S Baron-Cohen, B Chakrabarti