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I am a Stroke Association Senior Clinical Lecturer in Cerebrovascular Medicine and Honorary Consultant in Stroke Medicine at Addenbrooke's Hospital. My research investigates atherosclerosis (the hardening of blood vessels as we age), how inflammation within atherosclerosis may affect the brain, and how these processes relate to an individual's overall health (in particular the amount of physiological reserve an individual has to withstand and recover from an illness - a syndrome termed 'frailty'). I lead research programmes investigating how frailty affects treatments and outcomes after stroke, imaging studies to identify carotid atherosclerotic plaques that may cause a stroke, and drug studies where we are repurposing existing drugs used in other conditions to treat atherosclerosis and stroke. My research uses Computed Tomography (CT), Positron Emission Tomography (PET), and Magnetic Resonance Imaging (MRI) to image blood vessels and the brain. This research is a collaboration between the Departments of Clinical Neurosciences, Medicine (Cardiovascular Medicine), and Radiology within the School of Clinical Medicine. Our research has been recognised by awards from the British Atherosclerosis Society, Wellcome Trust, Royal College of Physicians, British Association of Stroke Physicians, Royal Society of Medicine, and British Heart Foundation. Our work has been supported by the Stroke Association, Dunhill Medical Trust, and British Heart Foundation. I hold an honorary clinical post providing clinical care within the Stroke Department at the Cambridge University Hospitals NHS Foundation Trust and am involved in the recruitment of participants into hyper-acute stroke trials. I am an enthusiastic medical educator, leading both the Cambridge INSPIRE Programme and Student Selected Component of the Clinical Medicine course that develop an understanding of medical research and promote clinical academic careers. I am the Director of Studies in Pre-Clinical Medicine at Wolfson College.
A PET/CT scan showing a 'hot' carotid atherosclerotic plaque.