Other Interdiciplinary Incentives

  • Neuroscience
  • Research Focus


  • CNS Repair
  • Axon Regeneration
  • Gene Therapy
  • Cell Biology
  • Membrane Trafficking
  • Clinical Conditions

  • Glaucoma
  • Spinal cord injury
  • Traumatic brain injury
  • Equipment & Techniques

  • Cell culture
  • Confocal microscopy
  • Fluorescence microscopy
  • Science Culture

  • Teaching
  • Back

    Dr Richard Eva

    University Position
    Honorary Fellow
    Dr Richard Eva is pleased to consider applications from prospective PhD students.


    My lab is focused on regeneration and protection of the injured or diseased central nervous system. We study fundamental neuronal cell biology and develop gene therapy candidates for eye disease or spinal cord injury. Our work investigates developmentally regulated axon transport mechanisms that limit the delivery of regenerative proteins and organelles. We find that overcoming these transport limitations can increase regenerative ability. We use fluorescence microscopy, live cell imaging, molecular and cellular techniques to study neuronal and axonal signalling and trafficking pathways, and combine these studies with models of CNS injury and disease. These studies are identifying neuroprotective genes that stimulate axon regeneration in the spinal cord and optic nerve.

    Satellite Golgi in Axons and Dendrites


    Key Publications

    Protrudin functions from the endoplasmic reticulum to support axon regeneration in the adult CNS.

    Journal: Nat Commun
    E-pub date: 5 Nov 2020
    Authors: V Petrova, CS Pearson, J Ching, JR Tribble, AG Solano, Y Yang, FM Love, RJ Watt, A Osborne, E Reid, PA Williams, KR Martin, HM Geller, R Eva, JW Fawcett

    PI 3-kinase delta enhances axonal PIP3 to support axon regeneration in the adult CNS.

    Journal: EMBO Mol Med
    E-pub date: 7 Aug 2020
    Authors: B Nieuwenhuis, AC Barber, RS Evans, CS Pearson, J Fuchs, AR MacQueen, S van Erp, B Haenzi, LA Hulshof, A Osborne, R Conceicao, TZ Khatib, SS Deshpande, J Cave, C Ffrench-Constant, PD Smith, K Okkenhaug, BJ Eickholt, KR Martin, JW Fawcett, R Eva


    Axonal Organelles as Molecular Platforms for Axon Growth and Regeneration after Injury.

    Journal: Int J Mol Sci
    E-pub date: 11 Feb 2021
    Authors: V Petrova, B Nieuwenhuis, JW Fawcett, R Eva

    ARF6 and Rab11 as intrinsic regulators of axon regeneration.

    Journal: Small GTPases
    E-pub date: 1 Nov 2020
    Authors: B Nieuwenhuis, R Eva

    Linking axon transport to regeneration using in vitro laser axotomy.

    Journal: Neural Regen Res
    E-pub date: 1 Mar 2018
    Authors: B Nieuwenhuis, R Eva

    Selective rab11 transport and the intrinsic regenerative ability of CNS axons.

    Journal: Elife
    E-pub date: 8 Aug 2017
    Authors: H Koseki, M Donegá, BY Lam, V Petrova, S van Erp, GS Yeo, JC Kwok, C Ffrench-Constant, R Eva, JW Fawcett