College Peterhouse
Research Theme Brains and Machines
Research Focus


  • 31P MRS
  • 7T MRI
  • AI
  • Alzheimer's Disease
  • Automated Image Assessment
  • Bayesian
  • Energy Metabolism
  • Metabolism
  • Brain Imaging
  • Diffusion Imaging
  • Functional Imaging
  • Imaging
  • Magnetic Resonance Imaging
  • Vascular Imaging
  • Clinical Conditions

  • Other 
  • Cancers
  • Brain cancer
  • Equipment & Techniques

  • Magnetic resonance imaging (MRI)
  • Science Culture

  • Mentorship
  • Open Access
  • Open-Source Science
  • Teaching
  • Back

    Professor Chris Rodgers

    University Position
    Professor Chris Rodgers is pleased to consider applications from prospective PhD students.


    I am a Professor of Biomedical Imaging and Head of 7T MRI Physics. My main expertise is in creating new methods for Magnetic Resonance Imaging (MRI) and Magnetic Resonance Spectroscopy (MRS). My group focus on ultra-high field (7T) MRI using the Siemens 7T Terra MRI scanner at the Wolfson Brain Imaging Centre. We push the boundaries of MRI techniques and translate the latest methods ready for use in clinical studies in collaboration with colleagues in Clinical Neurosciences and elsewhere. My group have active projects in parallel transmit MRI funded by Siemens where we have recently patented two new algorithms to improve the uniformity of 7T MRI and reduce RF heating of participants. We lead the "MITI" study which is testing whether the new drug dapagliflozin acts by restoring cardiac energy metabolism in patients with heart failure and type 2 diabetes. We collaborate with Prof Markus' group to study the mechanisms of cerebral small vessel disease. We collaborate with Prof Brindle and Prof Mair to apply deuterium metabolic imaging in patients with brain tumours. We collaborate with Prof Rowe and Prof O'Brien and Dr Matys to study changes in glycolysis in Alzheimer's disease also using deuterium metabolic imaging. We collaborate with Dr Cope on a study using 7T MRI to help detect the lesions responsible for drug-resistant focal epilepsy. I welcome applications for new PhD students, undergraduate students and for lab visits or summer projects.

    Illustration of our new Bayesian Optimisation approach to parallel transmit pulse design - the BOGAT algorithm. This work won a Summa Cum Laude Merit Award at ISMRM 2023.

    Key Publications

    Retained Metabolic Flexibility of the Failing Human Heart.

    Journal: Circulation
    E-pub date: 11 Jul 2023
    Authors: WD Watson, PG Green, AJM Lewis, P Arvidsson, GL De Maria, H Arheden, E Heiberg, WT Clarke, CT Rodgers, L Valkovič, S Neubauer, N Herring, OJ Rider

    Visualisation of lenticulostriate arteries using contrast-enhanced time-of-flight magnetic resonance angiography at 7 Tesla.

    Journal: Scientific Reports
    E-pub date: 24 Nov 2022
    Authors: CN Osuafor, C Rua, AD Mackinnon, M Egle, P Benjamin, DJ Tozer, CT Rodgers, HS Markus

    Parallel transmit (pTx) with online pulse design for task-based fMRI at 7 T.

    Journal: Magn Reson Imaging
    E-pub date: 1 Nov 2022
    Authors: B Ding, I Dragonu, C Rua, JD Carlin, AD Halai, P Liebig, R Heidemann, MM Correia, CT Rodgers

    A protocol for ultra-high field laminar fMRI in the human brain.

    Journal: STAR Protoc
    E-pub date: 18 Jun 2021
    Authors: K Jia, E Zamboni, C Rua, NR Goncalves, V Kemper, AKT Ng, CT Rodgers, G Williams, R Goebel, Z Kourtzi

    Multi-centre, multi-vendor 7 Tesla fMRI reproducibility of hand digit representation in the human somatosensory cortex

    E-pub date: 26 Mar 2021
    Authors: ID Driver, RM Sanchez Panchuelo, O Mougin, M Asghar, J Kolasinski, WT Clarke, C Rua, AT Morgan, A Carpenter, K Muir, D Porter, CT Rodgers, S Clare, RG Wise, R Bowtell, ST Francis

    Recurrent Processing Drives Perceptual Plasticity.

    Journal: Curr Biol
    E-pub date: 2 Nov 2020
    Authors: K Jia, E Zamboni, V Kemper, C Rua, NR Goncalves, AKT Ng, CT Rodgers, G Williams, R Goebel, Z Kourtzi

    Multi-centre, multi-vendor reproducibility of 7T QSM and R2* in the human brain: results from the UK7T study

    E-pub date: 1 Aug 2020
    Authors: C Rua, W Clarke, I Driver, O Mougin, A Morgan, S Clare, S Francis, K Muir, R Wise, A Carpenter, G Williams, J Rowe, R Bowtell, C Rodgers

    Using a whole-body 31P birdcage transmit coil and 16-element receive array for human cardiac metabolic imaging at 7T.

    Journal: PLoS One
    E-pub date: 1 Aug 2017
    Authors: L Valkovič, I Dragonu, S Almujayyaz, A Batzakis, LAJ Young, LAB Purvis, WT Clarke, T Wichmann, T Lanz, S Neubauer, MD Robson, DWJ Klomp, CT Rodgers

    OXSA: An open-source magnetic resonance spectroscopy analysis toolbox in MATLAB.

    Journal: PLoS One
    E-pub date: 1 Aug 2017
    Authors: LAB Purvis, WT Clarke, L Biasiolli, L Valkovič, MD Robson, CT Rodgers

    Dilated Cardiomyopathy: Phosphorus 31 MR Spectroscopy at 7 T.

    Journal: Radiology
    E-pub date: 1 Nov 2016
    Authors: VM Stoll, WT Clarke, E Levelt, A Liu, SG Myerson, MD Robson, S Neubauer, CT Rodgers

    Human cardiac 31P magnetic resonance spectroscopy at 7 Tesla.

    Journal: Magn Reson Med
    E-pub date: 31 Aug 2014
    Authors: CT Rodgers, WT Clarke, C Snyder, JT Vaughan, S Neubauer, MD Robson

    Chemical magnetoreception in birds: the radical pair mechanism.

    Journal: Proc Natl Acad Sci U S A
    E-pub date: 13 Jan 2009
    Authors: CT Rodgers, PJ Hore


    A temperature-controlled cooling system for accurate quantitative post-mortem MRI.

    Journal: Magn Reson Med
    E-pub date: 1 Dec 2023
    Authors: SW Rieger, A Hess, Y Ji, CT Rodgers, P Jezzard, KL Miller, W Wu

    Quantitative susceptibility mapping at 7 Tesla in COVID-19: mechanistic and outcome associations

    E-pub date: 1 Aug 2023
    Authors: C Rua, B Raman, CT Rodgers, VFJ Newcombe, A Manktelow, DA Chatfield, SJ Sawcer, JG Outtrim, VC Lupson, EA Stamatakis, GB Williams, WT Clarke, L Qiu, M Ezra, R McDonald, S Clare, M Cassar, S Neubauer, KD Ersche, ET Bullmore, DK Menon, K Pattinson, JB Rowe

    Cortical glutamate and GABA are related to compulsive behaviour in individuals with obsessive compulsive disorder and healthy controls.

    Journal: Nat Commun
    E-pub date: 27 Jun 2023
    Authors: M Biria, P Banca, MP Healy, E Keser, SJ Sawiak, CT Rodgers, C Rua, AMFLP de Souza, AA Marzuki, A Sule, KD Ersche, TW Robbins

    Assessment of Cardiac Energy Metabolism, Function, and Physiology in Patients With Heart Failure Taking Empagliflozin: The Randomized, Controlled EMPA-VISION Trial.

    Journal: Circulation
    E-pub date: 30 May 2023
    Authors: MJ Hundertmark, A Adler, C Antoniades, R Coleman, JL Griffin, RR Holman, H Lamlum, J Lee, D Massey, JJJJ Miller, JE Milton, S Monga, FE Mózes, A Nazeer, B Raman, O Rider, CT Rodgers, L Valkovič, E Wicks, M Mahmod, S Neubauer

    Compartment-based reconstruction of 3D acquisition-weighted 31 P cardiac magnetic resonance spectroscopic imaging at 7 T: A reproducibility study.

    Journal: NMR Biomed
    E-pub date: 12 Apr 2023
    Authors: A Tyler, J Ellis, JYC Lau, JJ Miller, PA Bottomley, CT Rodgers, DJ Tyler, L Valkovič

    Path integration selectively predicts midlife risk of Alzheimer’s disease.

    E-pub date: 3 Feb 2023
    Authors: C Newton, M Pope, C Rua, R Henson, Z Ji, N Burgess, CT Rodgers, M Stangl, M-E Dounavi, A Castegnaro, I Koychev, P Malhotra, T Wolbers, K Ritchie, CW Ritchie, J O'Brien, L Su, D Chan, PREVENT Dementia Research Programme

    Maternal Cardiac Changes in Women With Obesity and Gestational Diabetes Mellitus.

    Journal: Diabetes Care
    E-pub date: 1 Dec 2022
    Authors: S Thirunavukarasu, F Ansari, R Cubbon, K Forbes, C Bucciarelli-Ducci, DE Newby, MR Dweck, OJ Rider, L Valkovič, CT Rodgers, DJ Tyler, A Chowdhary, N Jex, S Kotha, L Morley, H Xue, P Swoboda, P Kellman, JP Greenwood, S Plein, T Everett, E Scott, E Levelt

    Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses.

    Journal: Brain
    E-pub date: 21 Nov 2022
    Authors: EJ Needham, AL Ren, RJ Digby, EJ Norton, S Ebrahimi, JG Outtrim, DA Chatfield, AE Manktelow, MM Leibowitz, VFJ Newcombe, R Doffinger, G Barcenas-Morales, C Fonseca, MJ Taussig, RM Burnstein, RJ Samanta, C Dunai, N Sithole, NJ Ashton, H Zetterberg, M Gisslén, A Edén, E Marklund, PJM Openshaw, J Dunning, MJ Griffiths, J Cavanagh, G Breen, SR Irani, A Elmer, N Kingston, C Summers, JR Bradley, LS Taams, BD Michael, ET Bullmore, KGC Smith, PA Lyons, AJ Coles, DK Menon, Cambridge NeuroCOVID Group, CITIID-NIHR COVID-19 BioResource Collaboration, Cambridge NIHR Clinical Research Facility

    Substantia nigra ferric overload and neuromelanin loss in Parkinson’s disease measured with 7T MRI

    E-pub date: 1 Aug 2021
    Authors: C Rua, C O’Callaghan, R Ye, F Hezemans, L Passamonti, S Jones, G Williams, C Rodgers, J Rowe

    An in vivo probabilistic atlas of the human locus coeruleus at ultra-high field.

    Journal: Neuroimage
    E-pub date: 15 Jan 2021
    Authors: R Ye, C Rua, C O'Callaghan, PS Jones, FH Hezemans, SS Kaalund, KA Tsvetanov, CT Rodgers, G Williams, L Passamonti, JB Rowe

    GABA and glutamate deficits from frontotemporal lobar degeneration are associated with disinhibition.

    Journal: Brain
    E-pub date: 5 Dec 2020
    Authors: AG Murley, MA Rouse, PS Jones, R Ye, FH Hezemans, C O'Callaghan, P Frangou, Z Kourtzi, C Rua, TA Carpenter, CT Rodgers, JB Rowe

    Correcting for Superficial Bias in 7T Gradient Echo fMRI

    E-pub date: 22 Nov 2020
    Authors: P Huang, MM Correia, C Rua, CT Rodgers, RN Henson, JD Carlin

    Rapid, $B_1$-insensitive, dual-band quasi-adiabatic saturation transfer with optimal control for complete quantification of myocardial ATP flux

    E-pub date: 10 Aug 2020
    Authors: JJ Miller, L Valkovič, M Kerr, KN Timm, W Watson, JYC Lau, A Tyler, C Rodgers, PA Bottomley, LC Heather, DJ Tyler

    Recurrent processing drives experience-dependent plasticity for perceptual decisions

    E-pub date: 1 Aug 2020
    Authors: K Jia, E Zamboni, V Kemper, C Rua, N Reis Goncalves, AKT Ng, C Rodgers, G Williams, R Goebel, Z Kourtzi

    Feasibility of absolute quantification for 31 P MRS at 7 T.

    Journal: Magn Reson Med
    E-pub date: 1 Jul 2019
    Authors: LAB Purvis, L Valkovič, MD Robson, CT Rodgers

    Saturation recovery allows T1 mapping in the human heart at 7T with a commercial MRI scanner

    Journal: Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    E-pub date: 1 Jan 2015
    Authors: CT Rodgers, Y Tao, SK Piechnik, A Liu, JM Francis, S Neubauer, MD Robson

    Inversion recovery at 7 T in the human myocardium: measurement of T(1), inversion efficiency and B(1) (+).

    Journal: Magn Reson Med
    E-pub date: 1 Oct 2013
    Authors: CT Rodgers, SK Piechnik, LJ Delabarre, P-F Van de Moortele, CJ Snyder, S Neubauer, MD Robson, JT Vaughan

    Effects of disorder and motion in a radical pair magnetoreceptor.

    Journal: J R Soc Interface
    E-pub date: 6 Apr 2010
    Authors: JCS Lau, N Wagner-Rundell, CT Rodgers, NJB Green, PJ Hore

    Derivatives of spin dynamics simulations.

    Journal: J Chem Phys
    E-pub date: 21 Dec 2009
    Authors: I Kuprov, CT Rodgers

    Derivatives of spin dynamics simulations

    E-pub date: 19 Oct 2009
    Authors: I Kuprov, CT Rodgers

    Radiofrequency polarization effects in low-field electron paramagnetic resonance.

    Journal: Phys Chem Chem Phys
    E-pub date: 21 Aug 2009
    Authors: CJ Wedge, CT Rodgers, SA Norman, N Baker, K Maeda, KB Henbest, CR Timmel, PJ Hore